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P53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo

(Cell Reports 3, 1512–1525; May 30, 2013)

In the originally published paper, the CC3 panel for the +/+ sample in Figure 6E was inadvertently duplicated from the TUNEL panel of the +/RR sample during figure assembly. The authors have retrieved the correct CC3 image for the +/+ sample and assembled a corrected version of Figure 6E, which is provided below. The authors apologize for the error.

Engineering the first reusable launchpads on the moon

Engineers need good data to build lasting things. Even the designers of the Great Pyramids knew the limestone they used to build these massive structures would be steady when stacked on top of one another, even if they didn’t have tables of the compressive strength of those stones.

But when attempting to build structures on other worlds, such as the moon, engineers don’t yet know much about the local materials. Still, due to the costs of getting large amounts of materials off of Earth, they will need to learn to use those materials even for critical applications like a landing pad to support the landing / ascent of massive rockets used in re-supply operations.

A new paper published in Acta Astronautica from Shirley Dyke and her team at Purdue University describes how to build a lunar landing pad with just a minimal amount of prior knowledge of the material properties of the regolith used to build it.

Visual awareness study unlocks interplay between attention and consciousness

A new study led by Dr. Jiang Yi from the Institute of Psychology of the Chinese Academy of Sciences has revealed the first clear evidence that visual awareness acts as a “conductor” that refines the speed, precision, and neural coordination of attentional rhythmic sampling.

Published in Nature Communications on Nov. 17, this study resolves a long-standing mystery about the interplay between attention and consciousness, opening new avenues for understanding cognitive function and deficits.

AMD and Google Tap Samsung’s Texas Fab for AI Chips

Advanced Micro Devices AMD-0.09% ▼ and Alphabet GOOGL +1.61% ▲ are in talks with Samsung Electronics SSNLF +54.05% ▲ to build next-gen chips in Texas. Both companies are exploring the use of Samsung’s new factory in Taylor, Texas, to manufacture 2-nanometer chips. These chips are expected to be the most advanced available when the plant is ready in 2026.

Dietary restriction fuels T-cells with ketones, boosting their cancer-fighting stamina

Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators. The findings lay the groundwork for developing dietary strategies to boost the effects of a powerful class of cancer immunotherapies.

“Growing evidence suggests dietary restriction has anti-cancer effects but the ‘why and how’ are not well understood. Our new study reveals one way this relationship may work: by providing T cells, the soldiers of the immune system, with the right mix of nutrients to more effectively fight cancer,” said Russell Jones, Ph.D., chair of VAI’s Department of Metabolism and Nutritional Programming and corresponding author of the study.

“Additional research is needed but we are hopeful these insights can inform evidence-based dietary guidelines to improve the effectiveness of immune-based cancer treatments.”

NASA-JAXA XRISM finds elemental bounty in supernova remnant

For the first time, scientists have made a clear X-ray detection of chlorine and potassium in the wreckage of a star using data from the Japan-led XRISM (X-ray Imaging and Spectroscopy Mission) spacecraft.

The Resolve instrument aboard XRISM, pronounced “crism,” discovered these elements in a supernova remnant called Cassiopeia A or Cas A, for short. The expanding cloud of debris is located about 11,000 light-years away in the northern constellation Cassiopeia.

“This discovery helps illustrate how the deaths of stars and life on Earth are fundamentally linked,” said Toshiki Sato, an astrophysicist at Meiji University in Tokyo. “Stars appear to shimmer quietly in the night sky, but they actively forge materials that form planets and enable life as we know it. Now, thanks to XRISM, we have a better idea of when and how stars might make crucial, yet harder-to-find, elements.”

From Decoherence to Coherent Intelligence: A Framework for the Emergence of AI Structure through Recursive Reasoning

This paper develops a thermodynamic framework for understanding the coherence of both biological and artificial cognition. We formalize thermodynamic coherence as an expression of information processing constrained by entropy and temperature, establishing a quantitative link between physical energy states and cognitive stability. Building on foundational concepts from statistical mechanics, quantum biology, and information theory, we argue that intelligence emerges as an ordered process, one that locally resists entropy through orderly reasoning work that generates coherent structure. The resulting framework is applied to wave function collapse, consciousness models, and machine reasoning, showing that coherence serves as a universal condition for stable cognition across domains.

Inventor and futurist talks his hopes for the advancement of AI and technology

Ray Kurzweil is an acclaimed inventor, futurist and author. In his newest book, “The Singularity is Nearer,” he dives into the future date where humans and machines eventually merge. Jeff Glor has more from their conversation. “CBS Saturday Morning” co-hosts Jeff Glor, Michelle Miller and Dana Jacobson deliver two hours of original reporting and breaking news, as well as profiles of leading figures in culture and the arts. Watch “CBS Saturday Morning” at 7 a.m. ET on CBS and 8 a.m. ET on the CBS News app. Subscribe to “CBS Mornings” on YouTube: / cbsmornings Watch CBS News 24/7: https://cbsnews.com/live/ Download the CBS News app: https://cbsnews.com/mobile/ Follow “CBS Mornings” on Instagram: / cbsmornings Like “CBS Mornings” on Facebook: / cbsmornings Follow “CBS Mornings” on Twitter: / cbsmornings Subscribe to our newsletter: https://cbsnews.com/newsletters/ Try Paramount+ free: https://paramountplus.com/?ftag=PPM-0… For video licensing inquiries, contact: licensing@veritone.com

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