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From Mammoth Revival to Human Fertility with Dr. Eriona Hysolli | Singularity University

Join us for an exclusive 1-hour conversation with Dr. Eriona Hysolli, the visionary scientist bridging de-extinction technology and the future of human reproduction. Recognized by Time100 Next for her groundbreaking work reviving the woolly mammoth, Dr. Hysolli brings a unique perspective to reproductive biotechnology that you won’t find anywhere else.

In this informal Q&A session, we’ll explore how cutting-edge technologies originally developed for species conservation are now revolutionizing human fertility treatments. Dr. Hysolli will share insights on:
The latest breakthroughs in synthetic embryos and artificial wombs.
How in vitro gametogenesis could transform infertility treatment.
Lessons from mammoth de-extinction that apply to human reproductive health.
The intersection of genome engineering and fertility solutions.
Near-term commercial applications in reproductive biotechnology.

Drawing from her pioneering work at Yale, George Church’s lab at Harvard, and as Head of Biological Sciences at Colossal Biosciences, Dr. Hysolli offers a rare glimpse into technologies that could redefine human reproduction within the next decade.

The session will feature a moderated discussion followed by audience Q&A. Whether you’re an investor, entrepreneur, healthcare professional, or simply fascinated by the future of fertility, this conversation will provide essential insights into one of biotechnology’s most promising frontiers.

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Implantable bioelectronics and wearable sensors for kidney health and disease

Advances in biosensor technology have the potential to enable continuous, non-invasive monitoring of kidney health through wearable and implantable systems. Non-invasive microfluidic systems have demonstrated utility in the detection of kidney-relevant biomarkers in peripheral body fluids such as sweat, interstitial fluid, tears and saliva, whereas implantable systems permit the direct measurement of biophysical tissue properties including tissue oxygenation, perfusion and temperature.

Heavy Drinkers Face Higher Risk of Brain Lesions And Alzheimer’s Markers

Alcohol is notoriously bad for health, and a recent study might add “long-term effects on brain health” to the growing list of ways drinking can cause harm.

The research, led by scientists at the University of São Paulo in Brazil, investigated the impact of regular drinking by examining brain autopsy data from 1,781 individuals, correlating findings with their reported drinking habits.

After adjusting for sociodemographic and clinical variables, like smoking and physical activity, the team found that the heaviest drinkers had a 133 percent higher risk of developing vascular brain lesions compared to non-drinkers.

UChicago scientists invent breakthrough device to detect airborne signs of disease

If you’ve ever sat waiting at the doctor’s office to give a blood sample, you might have wished there was a way to find the same information without needles.

But for all the medical breakthroughs of the 20th century, the best way to detect molecules has remained through liquids, such as blood. New research from the University of Chicago, however, could someday put a pause on pinpricks. A group of scientists announced they have created a small, portable device that can collect and detect airborne molecules—a breakthrough that holds promise for many areas of medicine and public health.

The researchers envision the device, nicknamed ABLE, could detect airborne viruses or bacteria in hospital or public spaces, improve neonatal care or allow people with diabetes to read glucose levels from their breath. The entire device is just four by eight inches across.


Portable tech captures molecules in breath to aid medical care from diabetes to at-risk newborn development.

What Shapes the Lives of the Gut’s Microbial Inhabitants

A biophysical model sheds light on how the subtle interplay of fluid dynamics and bacterial growth controls the fluctuating population of microbes in the human gut.

The human body harbors large numbers of bacteria—about as many as human cells—most of which are located in the gut, mainly in the colon. Together, diverse microorganisms including multiple species and strains of bacteria constitute the gut microbiota, which is thought to play a central role in human health, affecting the immune response and the progression of different diseases. However, despite a vast body of microbiota studies based on gene sequencing and on experiments with animal models, the dynamics of microbial populations in the human gut remain poorly understood. Alinaghi Salari of the University of Toronto and James Cremer of Stanford University have now proposed a biophysical model of the gut environment that incorporates a broad set of features of the human large intestine [1].

Scientists discover unknown organelle inside our cells

The discovery of an unknown organelle inside our cells could open the door to new treatments for devastating inherited diseases.

The , a type of specialized structure, has been dubbed a “hemifusome” by its discoverers at the University of Virginia School of Medicine and the National Institutes of Health. This little organelle has a big job helping our cells sort, recycle and discard important cargo within themselves, the scientists say. The new discovery could help scientists better understand what goes wrong in genetic conditions that disrupt these essential housekeeping functions.

“This is like discovering a new recycling center inside the cell,” said researcher Seham Ebrahim, Ph.D., of UVA’s Department of Molecular Physiology and Biological Physics. “We think the hemifusome helps manage how cells package and process material, and when this goes wrong, it may contribute to diseases that affect many systems in the body.”

Compute-in-memory chip shows promise for enhanced efficiency and privacy in federated learning systems

In recent decades, computer scientists have been developing increasingly advanced machine learning techniques that can learn to predict specific patterns or effectively complete tasks by analyzing large amounts of data. Yet some studies have highlighted the vulnerabilities of some AI-based tools, demonstrating that the sensitive information they are fed could be potentially accessed by malicious third parties.

A machine learning approach that could provide greater data privacy is federated learning, which entails the collaborative training of a shared neural network by various users or parties that are not required to exchange any raw data with each other. This technique could be particularly advantageous when applied in sectors that can benefit from AI but that are known to store highly sensitive user data, such as health care and finance.

Researchers at Tsinghua University, the China Mobile Research Institute, and Hebei University recently developed a new compute-in-memory chip for federated learning, which is based on memristors, non-volatile electronic components that can both perform computations and store information, by adapting their resistance based on the electrical current that flowed through them in the past. Their proposed chip, outlined in a paper published in Nature Electronics, was found to boost both the efficiency and security of federated learning approaches.

Simple nasal swab test could cut costly virus screenings in high-risk settings

The COVID-19 pandemic yielded important advances in testing for respiratory viruses, but it also exposed important unmet needs in screening to prevent the spread of infections in high-risk settings.

While PCR () tests are the gold standard for detecting viral infections, they remain a challenge for large numbers of people in places vulnerable to outbreaks—such as health care centers and nursing homes—due to and the fact that different tests are required for each virus.

A new Yale study, however, finds that an alternate strategy—using a nasal swab to screen for an antiviral protein produced by the body as a defense against infection—can be an effective method for ruling out respiratory infections, limiting PCR testing only to those most likely to be infected, at a fraction of the cost.

Synthetic ‘killswitch’ uncovers hidden world of cellular condensates

Researchers at the Max Planck Institute for Molecular Genetics have developed a novel synthetic micropeptide termed the “killswitch” to selectively immobilize proteins within cellular condensates, unveiling crucial connections between condensate microenvironments and their biological functions.

Biomolecular condensates are specialized regions inside cells, existing without membranes, where critical biochemical reactions occur. Their importance in health and disease is well established, including roles in cancer progression and viral infection.

Methods to precisely probe and manipulate condensates in living cells remain limited. Existing strategies lack specificity, either dissolving condensates indiscriminately or requiring artificial protein overexpression, which obscures the natural behavior of native cellular proteins.