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Scientists believe that they may have identified the cause of so many unexplained cancers.
Scientists believe they have made a breakthrough in finding the cause of certain cancers. Credit: Flying Colours Ltd / Getty
Today’s robots perform safety checks at industrial plants, conduct quality control in manufacturing, and are even starting to keep hospital patients company.
But soon — perhaps very soon — these increasingly humanlike machines will handle more sophisticated tasks, freeing up people while raising complex questions about the roles of artificial intelligence that are gaining attention.
At a panel hosted by the American Association of Retired Persons at this week’s Consumer Electronics Show (CES), experts described the next five years as a period where robots transition primarily from industrial sites to service settings, helping to address a worsening health care labor crunch.
For decades, scientists have been trying to develop therapeutics for people living with Alzheimer’s disease, a progressive neurodegenerative disease that is characterized by cognitive decline. Given the global rise in cases, the stakes are high. A study published in The Lancet Public Health reports that the number of adults living with dementia worldwide is expected to nearly triple, to 153 million in 2050. Alzheimer’s disease is a dominant form of dementia, representing 60 to 70 percent of cases.
Recent approvals by the Food and Drug Administration have focused on medications that shrink the sticky brain deposits of a protein called amyloid beta. The errant growth of this protein is responsible for triggering an increase in tangled threads of another protein called tau and the development of Alzheimer’s disease — at least according to the dominant amyloid cascade hypothesis, which was first proposed in 1991.
Over the past few years, however, data and drugs associated with the hypothesis have been mired in various controversies relating to data integrity, regulatory approval, and drug safety. Nevertheless, the hypothesis still dominates research and drug development. According to Science, in fiscal year 2021 to 2022, the National Institutes of Health spent some $1.6 billion on projects that mention amyloids, about 50 percent of the agency’s overall Alzheimer’s funding. And a close look at the data for recently approved drugs suggests the hypothesis is not wrong, so much as incomplete.
Improving Global Resilience Against Emerging Infectious Threats — Dr. Nahid Bhadelia, MD — Founding Director, Center on Emerging Infectious Diseases (CEID), Boston University.
Dr. Nahid Bhadelia, MD, MALD is a board-certified infectious diseases physician who is the Founding Director of BU Center on Emerging Infectious Diseases (https://www.bu.edu/ceid/about-the-cen…) as well an Associate Professor at the BU School of Medicine. She served the Senior Policy Advisor for Global COVID-19 Response for the White House COVID-19 Response Team in 2022–2023, where she coordinated the interagency programs for global COVID-19 vaccine donations from the United States and was the policy lead for Project NextGen, $5B HHS program aimed at developing next generation vaccines and treatments for pandemic prone coronaviruses. She also served as the interim Testing Coordinator for the White House MPOX Response Team. She is the Director and co-founder of Biothreats Emergence, Analysis and Communications Network (BEACON), an open source outbreak surveillance program.
Shaping The Culture & Conduct Of Science — Dr. Marcia McNutt Ph.D. — President, National Academy Of Sciences
Dr. Marcia McNutt, Ph.D. is President of the National Academy of Sciences (https://www.nasonline.org/directory-e…), where she also chairs the National Research Council, the operating arm of the National Academies of Sciences, Engineering, and Medicine, and serves a key role in advising our nation on various important issues pertaining to science, technology, and health.
A recent study highlights that significant health benefits and molecular adaptations from fasting are detectable after three days.
Recent findings show that prolonged fasting triggers significant and systematic changes across multiple organs in the body. These results highlight potential health benefits that extend beyond weight loss, but they also reveal that these impactful changes only begin to occur after three full days without food.
Health Benefits of Fasting Unveiled.
In a world grappling with a multitude of health threats—ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria—the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where these tests can be done anywhere, by anyone, using a device as small and portable as your smartwatch. To do that, you need microchips capable of detecting miniscule concentrations of viruses or bacteria in the air.
Summary: Researchers have developed a Genetic Progression Score (GPS) using artificial intelligence to predict the progression of autoimmune diseases from preclinical symptoms to full disease. The GPS model integrates genetic data and electronic health records to provide personalized risk scores, improving prediction accuracy by 25% to 1,000% over existing models.
This method identifies individuals at higher risk earlier, enabling timely interventions and better disease management. The framework could also be adapted to study other underrepresented diseases, offering a breakthrough in personalized medicine and health equity.
Scientists have identified a key nucleolar complex that could be instrumental in combating neurodegenerative diseases. This complex plays a critical role in maintaining cellular health by regulating protein homeostasis (proteostasis)—the process by which cells ensure proper protein balance and function.
Research reveals that suppressing this nucleolar complex significantly reduces the toxic effects of proteins associated with Alzheimer’s.
Alzheimer’s disease is a progressive neurological disorder that primarily affects older adults, leading to memory loss, cognitive decline, and behavioral changes. It is the most common cause of dementia. The disease is characterized by the buildup of amyloid plaques and tau tangles in the brain, which disrupt cell function and communication. There is currently no cure, and treatments focus on managing symptoms and improving quality of life.
Per-and polyfluorinated alkyl substances (PFAS) earn their “forever chemical” moniker by persisting in water, soil and even the human brain. This unique ability to cross the blood-brain barrier and accumulate in brain tissue makes PFAS particularly concerning, but the underlying mechanism of their neurotoxicity must be studied further.
To that end, a new study by University at Buffalo researchers has identified 11 genes that may hold the key to understanding the brain’s response to these pervasive chemicals commonly found in everyday items. The paper is published in the journal ACS Chemical Neuroscience.
These genes, some involved in processes vital for neuronal health, were found to be consistently affected by PFAS exposure, either expressing more or less, regardless of the type of PFAS compounds tested. For example, all compounds caused a gene key for neuronal cell survival to express less, and another gene linked to neuronal cell death to express more.
