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Candida auris spreads globally as drug resistance and virulence increase, review finds

Best advice is simply disinfect with vinegar because it kills it on contact.


The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new review by a Hackensack Meridian Center for Discovery and Innovation (CDI) scientist and colleagues.

But there are strategies available and underway to combat the invasive and drug-resistant germ, says the work in Microbiology and Molecular Biology Reviews.

The paper summarizes and analyzes the latest developments—and needs—in mycology in 2025. Neeraj Chauhan, Ph.D., of the CDI, is co-author with Anuradha Chowdhary, Ph.D., of the Medical Mycology Unit at the Vallabhbhai Patel Chest Institute at the University of Delhi, who is a global leader in identifying and combating fungal threats, and was one of the first scientists to identify C. auris as a major public health threat in India in 2014. Chowdhary is also a visiting researcher at the CDI.

Cold weather concerns: Doctor explains how winter affects children’s immunity and growth

Winter’s chill impacts children’s health, increasing illness and affecting growth due to reduced sunlight, indoor confinement, and dietary shifts. Experts advise parents to prioritize balanced nutrition, adequate sleep, and physical activity. Simple measures like hygiene, vaccinations, and sun exposure are crucial for keeping kids healthy and thriving throughout the colder months.

COVID-19 Leaves Lasting Changes in the Brain, Even After Full Recovery

Summary: Advanced imaging reveals that COVID-19 may cause lasting brain changes, even in people without ongoing symptoms, pointing to hidden neurological effects that could persist long after recovery.

COVID-19 affects more than the lungs. Research shows that even after people have fully recovered from the infection, the virus can cause significant changes in the brain, underscoring its lasting effects on neurological health.

COVID-19 is widely recognized for its impact on the lungs, but growing evidence shows that the virus can also cause lasting changes in the brain, even in people who have fully recovered. These findings point to potential long-term neurological consequences that extend beyond the acute phase of the illness.

Cleaving mechanically stressed DNA

Wang and Wu et al. identify soluble interleukin-6 receptor (sIL-6R) as a key exerkine determining the efficacy of exercise in diabetes prevention, which is modulated by microbiome-dependent leucine through a gut-adipose tissue axis. Pharmacological or dietary interventions targeting adipocyte-secreted sIL-6R may help to improve the metabolic outcomes in those exercise non-responders.

Cross-regulation between the nervous system and type 2 immunity

In a Science Immunology Review from earlier this year, researchers discuss how interactions between the nervous and immune systems could impact neurological disorders and allergy-related behaviors like food avoidance.


The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters, suggesting previously unidentified therapeutic avenues.

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Scientists have long suspected that a small population of cells survives treatment and regenerates the tumor. These “cancer stem cells” are thought to resist conventional therapies, allowing the disease to return even after the visible tumor has been removed.

Previous attempts to identify gastric cancer stem cells using other protein markers, such as CD44 or CD133, yielded inconsistent results. These markers often appeared on healthy cells as well or did not fully account for tumor behaviour.

The team discovered that AQP5 reliably marks the cancer stem cells in gastric tumors. Aquaporins are proteins that form channels in cell membranes to control the movement of water into and out of cells. While AQP5 was previously known to mark stem cells in healthy gastric tissue, this study shows it also identifies the specific cells responsible for driving tumor growth, spread, and recurrence.

Importantly, AQP5 does more than simply mark these cells; it actively contributes to their aggressive behavior.

The researchers found that cells with AQP5 were capable of forming new tumors, while cells without AQP5 rarely did so. Most significantly, when they used a targeted method to eliminate only the AQP5-expressing cells, tumors stopped growing or shrank entirely and did not recur. This held true even for cancers that had spread to other organs.


Scientists have identified the specific cells responsible for gastric cancer’s tendency to return after treatment. The study also demonstrated that eliminating these cells stops tumors from growing, even in advanced disease that has spread to other organs.

A Distinct New Type of Diabetes Is Officially Recognized

This year, the International Diabetes Federation (IDF) officially recognized a fifth form of diabetes, after decades of controversy. It’s now urging other health authorities, like the World Health Organization (WHO), to follow suit.

Type 5 diabetes is rarely discussed or researched, and yet it is thought to impact up to 25 million people worldwide, especially those in low-and middle-income nations where access to medical care is limited.

It was first described in 1955 in Jamaica, then forgotten about for many years. Even once it was acknowledged by the WHO in the 1980s, the diagnosis created controversy.

Researchers create world’s smallest programmable, autonomous robots

Researchers at the University of Pennsylvania and University of Michigan have created the world’s smallest fully programmable, autonomous robots: microscopic swimming machines that can independently sense and respond to their surroundings, operate for months and cost just a penny each.

Barely visible to the naked eye, each robot measures about 200 by 300 by 50 micrometers, smaller than a grain of salt. Operating at the scale of many biological microorganisms, the robots could advance medicine by monitoring the health of individual cells and manufacturing by helping construct microscale devices.

Powered by light, the robots carry microscopic computers and can be programmed to move in complex patterns, sense local temperatures and adjust their paths accordingly.

Scientists boost mitochondria to burn more calories

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health.

Obesity is a global epidemic and a risk factor for many diseases, including diabetes and cancer. Current obesity drugs require injections and can cause side effects, so a safe way to boost weight loss could deliver significant public health benefits.

The study, led by Associate Professor Tristan Rawling from the University of Technology Sydney (UTS), has just been published in Chemical Science, where it was highlighted as “pick of the week.”

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