(Cell Metabolism 34, 1999–2017.e1–e10; December 6, 2022)

We recently identified several errors during a routine review of the data associated with the published article.

In Figure 2A, the dataset corresponding to the Boyden chamber co-culture condition was inadvertently duplicated from the conditioned media dataset during the preparation of the source data files. The figure itself was generated using the correct raw experimental datasets at the time of analysis and plotting. Therefore, the quantitative results shown in the published figure remain accurate. We have now corrected the source data files by restoring the appropriate raw dataset for the Boyden chamber co-culture condition. The corrected source data are consistent with the originally reported results and do not affect the conclusions of the study.

Immunotherapies are a promising approach in the fight against cancer. Researchers at the Technical University of Munich (TUM) have developed a lab-on-a-chip system called CellTrap. It makes it possible to observe the interactions between immune cells and cancer cells at the single-cell level. The method is intended to reveal fundamental processes in cancer immunology and answer key questions. The technology is described in the journal RSC Advances.

Established laboratory tests mainly capture average values across many cells and show, for example, how many cancer cells survive after contact with immune cells. What happens in detail—how each cell reacts and interacts with others—remains hidden. However, to better understand the effectiveness of immunotherapies, the precise timing of a cell-cell interaction is often crucial: when contact, activation and, ultimately, the killing of the cancer cell occur.