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Ursula Eysin on Uncertainty and Future Scenarios

How do we turn uncertainty from a threat into an advantage?

Three years ago, I sat down with someone who has built her entire career around that question: Ursula Eysin, founder of Red Swan and one of the most multidimensional futurists I’ve ever met.

Ursula is a trained ballerina who speaks seven languages, reads chemistry books for fun, mentors startups, and teaches at five universities — and somehow still finds time to help leaders navigate the unknown with clarity and courage.

In this conversation, we dig into: • Why predicting the future is a powerless position • Scenario planning vs. futurism — and why leaders need both • How to reframe uncertainty as a strategic asset • What it truly means to connect as humans in an age of AI • And why strong, diverse leadership matters more than ever.

My favourite line from Ursula remains razor-sharp:

“Turn uncertainty into an advantage. See it as a gift. And connect to other people.”

If you’re steering a team, a company, or even your own life through volatility, this one is worth your time.

Aging alters the protein landscape in the brain — diet can counteract this

A study by the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena shows that the chemical composition of proteins in the brain undergoes fundamental changes with aging. In particular, ubiquitylation—a process that marks proteins and thus controls their activity and degradation—undergoes drastic changes in the aging brain. Interestingly, a change in nutrition, such as short-term dietary restriction, can partially revert some of these molecular patterns. These findings open up new opportunities to better understand the aging process of the brain and related diseases.

Airborne sensors map ammonia plumes in California’s Imperial Valley

A recent study led by scientists at NASA’s Jet Propulsion Laboratory in Southern California and the nonprofit Aerospace Corporation shows how high-resolution maps of ground-level ammonia plumes can be generated with airborne sensors, highlighting a way to better track the gas.

A key chemical ingredient of fine particulate matter—tiny particles in the air known to be harmful when inhaled—ammonia can be released through agricultural activities such as livestock farming and geothermal power generation as well as natural geothermal processes. Because it’s not systematically monitored, many sources of the pungent gas go undetected.

Published in Atmospheric Chemistry and Physics, the study focuses on a series of 2023 research flights that covered the Imperial Valley to the southeast of the Salton Sea in inland Southern California, as well as the Eastern Coachella Valley to its northwest. Prior satellite-based research has identified the Imperial Valley as a prolific source of gaseous ammonia.

From light to logic: First complete logic gate achieved in soft material using light alone

Researchers from McMaster University and the University of Pittsburgh have created the first functionally complete logic gate—a NAND gate (short for “NOT AND”)—in a soft material using only beams of visible light. The discovery, published in Nature Communications, marks a significant advance in the field of materials that compute, in which materials themselves process information without traditional electronic circuitry.

“This project has been part of my scientific journey for over a decade,” said first author Fariha Mahmood, who began studying the gels as an undergraduate researcher at McMaster and is now pursuing postdoctoral research at the University of Cambridge. “To see these materials not only respond to light but also perform a logic operation feels like watching the material ‘think.’ It opens the door to soft systems making decisions on their own.”

Mahmood is joined by authors Anna C. Balazs, distinguished professor of chemical and petroleum engineering, and Victor V. Yashin, research assistant professor at Pitt’s Swanson School of Engineering; and corresponding author Kalaichelvi Saravanamuttu, professor of chemistry and chemical biology at McMaster.

Coaxing bilayer graphene into a single diamond-like layer for industrial applications

Graphene’s enduring appeal lies in its remarkable combination of lightness, flexibility, and strength. Now, researchers have shown that under pressure, it can briefly take on the traits of one of its more glamorous carbon cousins.

By introducing nitrogen atoms and applying pressure, a team of scientists has coaxed bilayer grown through chemical vapor deposition (CVD) into a diamond-like phase—without the need for extreme heat. The finding, reported in Advanced Materials Technologies, shows a scalable way to create ultrathin coatings that combine the toughness of diamond with the processability of graphene.

New type of DNA damage discovered in our cells’ mitochondria

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC Riverside-led study are published today in the Proceedings of the National Academy of Sciences and have potential implications for a range of mitochondrial dysfunction-associated diseases, including cancer and diabetes.

Mitochondria have their own genetic material, known as mitochondrial DNA (mtDNA), which is essential for producing the energy that powers our bodies and sending signals within and outside cells. While it has long been known that mtDNA is prone to damage, scientists didn’t fully understand the biological processes. The new research identifies a culprit: glutathionylated DNA (GSH-DNA) adducts.

An adduct is a bulky chemical tag formed when a chemical, such as a carcinogen, attaches directly to DNA. If the damage isn’t repaired, it can lead to DNA mutations and increase the risk of disease.

Sharper MRI scans may be on horizon thanks to new physics-based model

Researchers at Rice University and Oak Ridge National Laboratory have unveiled a physics-based model of magnetic resonance relaxation that bridges molecular-scale dynamics with macroscopic magnetic resonance imaging (MRI) signals, promising new insight into how contrast agents interact with water molecules. This advancement paves the way for sharper medical imaging and safer diagnostics using MRI.

The study is published in The Journal of Chemical Physics.

This new approach, known as the NMR eigenmodes framework, solves the full physical equations that can be used to interpret how water molecules relax around metal-based imaging agents, a task that previous models approximated. These findings could alter the development and application of new contrast agents in both medicine and materials science.

From artificial organs to advanced batteries: A breakthrough 3D-printable polymer

A new type of 3D-printable material that gets along with the body’s immune system, pioneered by a University of Virginia research team, could lead to safer medical technology for organ transplants and drug delivery systems. It could also improve battery technologies.

The breakthrough is the subject of a new article published in the journal Advanced Materials, based on work done by the University of Virginia’s Soft Biomatter Laboratory, led by Liheng Cai, an associate professor of materials science and engineering and chemical engineering. The paper’s first author is Baiqiang Huang, a Ph.D. student in the School of Engineering and Applied Science.

Their research shows a way to change the properties of polyethylene glycol to make stretchable networks. PEG, as it’s known, is a material already used in many biomedical technologies such as tissue engineering, but the way PEG networks are currently produced—created in water by crosslinking linear PEG polymers, with the water removed afterward—leaves a brittle, crystallized structure that can’t stretch without losing its integrity.

Interpretable AI reveals key atomic traits for efficient hydrogen storage in metal hydrides

Hydrogen fuels represent a clean energy option, but a major hurdle in making its use more mainstream is efficient storage. Hydrogen storage requires either extremely high-pressure tanks or extremely cold temperatures, which means that storage alone consumes a lot of energy. This is why metal hydrides, which can store hydrogen more efficiently, are such a promising option.

To help accurately predict performance metrics of materials, researchers at Tohoku University used a newly established data infrastructure: the Digital Hydrogen Platform (DigHyd). DigHyd integrates more than 5,000 meticulously curated experimental records from the literature, supported by an AI language model. The work is published in the journal Chemical Science.

Leveraging this extensive database, researchers systematically explored physically interpretable models and found that fundamental atomic features— , electronegativity, molar density, and ionic filling factor—emerge as key descriptors. Other researchers can use this as a tool for guiding their materials design process, without having to go through a lengthy trial-and-error process in the lab to search for .

Green-synthesized zinc oxide nanoparticles from desert plants show broad antimicrobial activity

As drug-resistant infections continue to rise, researchers are looking for new antimicrobial strategies that are both effective and sustainable. One emerging approach combines nanotechnology with “green” chemistry, using plant extracts instead of harsh chemicals to produce metal oxide nanoparticles.

A new study published in Biomolecules and Biomedicine now reports that oxide nanoparticles (ZnONPs) biosynthesized from four desert plants with medicinal properties can inhibit a wide spectrum of bacteria, yeasts and filamentous fungi in laboratory tests. The work also links the plants’ rich phytochemical profiles to nanoparticle stability and potency, and uses computer modeling to explore how key compounds might interact with microbial targets.

The study is the first to produce ZnONPs from species that thrive in harsh, arid environments and are often under-used or even considered invasive. “By turning resilient desert plants into tiny zinc oxide particles, we were able to generate materials that are both eco-friendly to produce and surprisingly active against a range of microbes,” the authors write. “These green nanoparticles could form the basis for future antimicrobial formulations, pending further safety and efficacy testing.”

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