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Archive for the ‘aging’ category

Jun 15, 2018

Hong Kong Market Could Open Cash Flood Gates for U.S. Biotechs — Bioquark Inc.

Posted by in categories: aging, biotech/medical, business, economics, finance, health, innovation, life extension, neuroscience, science

Jun 11, 2018

Bioquark Inc. — “Living Forever” — Future Sandwich Podcast — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, cryonics, DNA, futurism, genetics, health, life extension, Peter Diamandis

Jun 9, 2018

Human Skeletal Muscle Aging and Mutagenesis

Posted by in categories: aging, DNA, genetics, health, life extension

Study based upon human skeletal muscle aging, mutagenesis, and the role of #satellite cells.

“A more comprehensive understanding of the interplay of stem cell–intrinsic and extrinsic factors will set the stage for improving cell therapies capable of restoring tissue homeostasis and enhancing muscle repair in the aged.”

Human aging has multiple effects on the human body. One of the effects of human aging is the reduction in skeletal muscle (SkM) function and a reduction in the number and activity of satellite cells (SCs), the resident stem cells. The whole genome of single SC clones of the leg muscle vastus lateralis from healthy individuals of different ages (21–78 years) was analyzed, to study the specific connection between SC aging and muscle impairment. In healthy adult muscle rapid increase of SCs is consistent with the accumulation rate of 13 somatic mutations per genome per year. Mutations typically do not happen in SkM-expressed genes because they are protected. However, as mutations in exons and promoters increase, genes involved in SC activity and muscle function are targeted which results in aging. Exons are coding sections of an RNA transcript, or the DNA encoding it, that are translated into protein. Proteins are the synthesis of molecules. A change in of a single base pair that caused the substitution of a different amino acid in the resulting protein (missense mutation) that was propagated to the muscle and detected in association with SC mutations affecting the whole tissue. #Somatic mutagenesis in SCs as a result is the driving force in the age related decline of SkM function.

Continue reading “Human Skeletal Muscle Aging and Mutagenesis” »

Jun 5, 2018

Can You Actually Hack Your DNA to Slow Down Aging? — Bioquark Inc. — Ira Pastor

Posted by in categories: aging, biotech/medical, DNA, genetics, health, innovation, life extension, neuroscience, science, transhumanism

http://www.thepathmag.com/can-you-actually-hack-your-dna-to-slow-down-aging/

Many technologies / interventions progressing down the development pathways in the coming years — but there are a lot of free, common sense adjustments you can make today:

Jun 5, 2018

Bioquark Inc. — Healthy Relationship Talk Radio — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, cryonics, disruptive technology, DNA, futurism, genetics, health, life extension

https://player.fm/series/healthy-relationship-talk-radio/cel…1-2018

Jun 5, 2018

Bioquark Inc. — Free Your Mind Podcast — Ira Pastor

Posted by in categories: aging, biotech/medical, business, DNA, education, finance, futurism, health, life extension, neuroscience

http://www.blogtalkradio.com/entrepreneursempower/2018/06/03…ira-pastor

May 22, 2018

Bioquark Inc. — Enterprise NOW! Podcast — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, business, disruptive technology, DNA, economics, finance, futurism, genetics

https://enterprise-now.biz/podcast/blog/ep-96-mother-nature-…ira-pastor

May 15, 2018

Bioquark Inc. — HumanOS Podcast — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, cryonics, disruptive technology, DNA, genetics, health, life extension, science

https://www.youtube.com/watch?v=qNSxkxyVptw

May 12, 2018

Bioquark Inc. — Future Fossils Podcast — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, cryonics, futurism, genetics, health, neuroscience, science, transhumanism

https://www.mindpodnetwork.com/future-fossils-72-ira-pastor-…animation/

May 8, 2018

Bioquark Inc. — Parents Are Hard To Raise Podcast — Ira Pastor

Posted by in categories: aging, bioengineering, biological, biotech/medical, DNA, futurism, health, life extension, neuroscience, science
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