Through substantial leadership turnover and workforce cuts, the FDA has continued to support the advanced therapy sector, actively working to remove obstacles to innovation.
Category: innovation
90% of Gamers Have Played a Remake or Remaster, Finds New Report
According to MTM, many respondents said that they find remakes and remasters “help them reconnect with positive, comforting feelings and memories that they had when they first played the game.”
However, the firm noted that others raised concerns about studios “taking an easy, repetitive route to market” and that these remakes come at the cost of “sacrificing innovative, new experiences that could redefine the industry.”
“Our report shows that there is a strong appeal for remakes and remasters, but it’s a tight balancing act for studios to get right,” said Martin Bradley, head of gaming at MTM.” Many of these games are far out-selling their original release.
How ancient philosophers would shape AI | Brendan McCord
We made this video in partnership with the Cosmos Institute, a network of thinkers and builders advancing human flourishing in the AI era.
Read the Cosmos Institute Substack ► https://bit.ly/3XK5T7k.
Follow Brendan McCord on X ► https://bit.ly/3Y9pFLb.
Artificial intelligence is transforming our world, prompting us to revisit fundamental philosophical questions about human existence and purpose. In this interview, Brendan McCord, founder of the Cosmos Institute, examines how philosophical insights from thinkers like Aristotle, John Stuart Mill, and Alexis de Tocqueville can inform our approach to AI, ensuring it enhances rather than undermines human flourishing.
McCord outlines three crucial steps to align AI with the principles of autonomy, reason, and decentralization. By drawing on ancient wisdom, we can navigate the complexities of modern technology and create a future where innovation and human values coexist.
Reflecting on the transformative ideas from Copernicus to Turing, this interview offers a roadmap for finding our place in the cosmos amidst the AI revolution. Explore how we can build a society that prioritizes human potential in the age of technology.
HD⁺ ions cooled to 18 mK yield most precise vibrational-rotational spectra to date
A research team from the Innovation Academy for Precision Measurement Science and Technology (APM) of the Chinese Academy of Sciences has made significant progress in precisely measuring the vibrational-rotational spectra of hydrogen molecular ions (HD⁺).
The researchers prepared a Be⁺-HD⁺ two-component ion Coulomb crystal at millikelvin temperatures in a linear ion trap. They developed an innovative quantum state preparation and spatially resolved fluorescence detection techniques and used these to measure the high-resolution vibrational-rotational transition spectra of HD⁺ molecular ions. Their findings were published in Physical Review A.
HD⁺ is the simplest heteronuclear molecular ion, composed of one proton, one deuteron, and one electron. Its vibrational-rotational transition energies can be precisely calculated, making it an ideal system for testing quantum electrodynamics (QED) theory and determining fundamental physical constants, such as the proton-electron mass ratio.
Reversing fibrosis: New research provides insight for novel therapies
Yale School of Medicine (YSM) researchers have made key breakthroughs in understanding how to treat fibrotic diseases such as scleroderma and graft-versus-host disease.
Fibrotic diseases are a group of conditions—often autoimmune—characterized by excessive tissue scarring. They can drastically hinder patients’ quality of life, and in some cases, they can be life-threatening— fibrosis contributes to approximately 45% of all deaths in developed nations. However, there are no effective treatments.
Now, in a study published in Blood, researchers have developed a monoclonal antibody that is showing promise as a new therapy for patients. And in a Nature Communications study, the same team discovered a signaling pathway that may be mediating fibrosis and could be a target for future therapies.
Sutskever’s List
“If you really learn all of these, you’ll know 90% of what matters today.” – Ilya Sutskever.
AI is transforming the world faster than we could have imagined. But how did we get here? AI guru Ilya Sutskever made the bold claim that most of what you need to know about modern AI is captured in 30 seminal research papers on deep learning.
What did Ilya see? Read through Sutskever’s List and you’ll uncover the breakthroughs, ideas, and mental models that shaped his vision and much more, all clearly explained and interpreted by veteran author and teacher Richard Heimann.
Improved method offers broader, faster detection of protein-ligand interactions
EMBL scientists have improved a protein analysis technique, significantly expanding its use and making it 100 times faster.
Swedish chemist Jöns Jacob Berzelius, in a letter to a fellow chemist, first suggested the name “proteins” for a particular class of biological substances, deriving it from the Greek word proteios, meaning “primary” or “of first importance.” Although scientists in the 1830s knew very little about proteins, it was already clear how essential they were to living organisms.
Long-known as the “workhorses of the cell,” proteins are responsible for powering nearly every function in the body. Often critical to this is their interactions with other small molecules known as ligands. In a new study published in Nature Structural and Molecular Biology, EMBL researchers introduce HT-PELSA, a high-throughput adaptation of an earlier tool that detects these interactions. This new tool can process samples at an unprecedented scale, a breakthrough that promises to accelerate drug discovery and our understanding of fundamental biological processes.