Lifeboat Foundation

Everyone knows it takes a male and a female to make a baby. But what a new study from the Chinese Academy of Sciences suggests is that maybe it doesn’t. In a new study, the team of scientists reports they did the seemingly impossible: Produce healthy baby mice from two mothers. The researchers describe their achievement in a breakthrough new paper in Cell Stem Cell.

The single-sex parent phenomenon has been observed naturally in reptiles, fish, amphibians, and invertebrates, but it was never thought to be possible in mammals, who reproduce differently. But as the team describe in their paper, all it took was overcoming the genetic limitations that usually make same-sex parenting impossible. The team, which also included researchers from Northeast Agricultural University in Harbin, China, used a combination of stem cells and CRISPR precision gene editing to produce healthy mice from two mothers. Interestingly, they tried the same with embryos from two fathers, but those offspring only lived a few days.

In the paper, they describe the bizarre, ingenious way the mouse embryos were formed using an egg from one mother a stem cell from another mother. The team’s breakthrough was figuring out how to manipulate the DNA of the stem cell so that the babies wouldn’t have birth defects.

Continue reading “Babies Born From Two Mothers Survive for First Time in Mouse Study” »

New research has revealed that fisetin – a natural flavonoid found in many fruits and vegetables – functions as an effective senolytic agent by clearing out damaged aging cells, improving health and extending lifespan.

As a Master’s student at University of Houston’s Sasakawa International Center for Space Architecture (SICSA), I was exposed to many interesting aspects of space exploration. One that I’m particularly intrigued about is the daily lives of astronauts, and their most mundane activities — how they sleep, eat, shower, exercise, work, etc. When the time came to choose what to focus on for my design thesis, I knew it would have something to do with habitation, community, and daily lives in space.

My undergrad was in architecture and urban studies with an equal emphasis on both. This gave me an understanding of how dwellings changed throughout the centuries in relation to the evolution of cities. I think in most cases, our definition of “home” is very intertwined with our definition of “city”. And I believe as humans set sail for the stars, this intertwining will stay strong. What defines a home and a city varies greatly from culture to culture, and changes with time. However, in a broad sense, a home is for your personal and intimate activities, alone or with close family members, and a city is a collection of private and public areas where the community can interact and coexist.

“It’s the most valuable specimen I have ever held in my life, monetarily and scientifically,” Sibescu said.

For double verification, a slice of it was sent to the Smithsonian Institution in Washington, DC, which validated it was in fact a meteorite, according to the press release.

Continue reading “A rock used as a doorstop for the past 30 years turns out to be a meteorite valued at $100K” »

Previous research published earlier this year in Nature Medicine involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer and Mayo Clinic investigators James L. Kirkland and Tamara Tchkonia, showed it was possible to reduce the burden of damaged cells, termed senescent cells, and extend lifespan and improve health, even when treatment was initiated late in life. They now have shown that treatment of aged mice with the natural product Fisetin, found in many fruits and vegetables, also has significant positive effects on health and lifespan.

Angus, a 1,000lb robot, rolls about the indoor farm on omnidirectional wheels.

Its main job is to shuttle maturing produce to another, as-yet unnamed robot, which transfers plants from smaller growing pods to larger ones.

Continue reading “Angus the robot could soon be cultivating your salads in a robo-farm” »

Pivot Bio just got a $70 million infusion from Bill Gates’s energy fund and other investors to launch its commercial product next year.

The science: The biotechnology company, based in Berkeley, California, is creating probiotics for plants. The firm’s researchers have identified microbes with a dormant ability to produce nitrogen, a crucial nutrient in synthetic fertilizer, and engineered them to reawaken and enhance it. For its initial product, Pivot Bio has created a liquid treatment for corn crops that can be applied when the seeds are planted.

The sell: In early field tests, patches treated with the microbes produce comparable yields to those relying on synthetic fertilizers. Pivot Bio’s pitch to farmers is that the product reduces work and complexity, because a single application takes less time than spraying multiple rounds of fertilizer.

Continue reading “Replacing fertilizer with plant probiotics could slash greenhouse gases” »

Previous research published earlier this year in Nature Medicine involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer and Mayo Clinic investigators James L. Kirkland and Tamara Tchkonia, showed it was possible to reduce the burden of damaged cells, termed senescent cells, and extend lifespan and improve health, even when treatment was initiated late in life. They now have shown that treatment of aged mice with the natural product Fisetin, found in many fruits and vegetables, also has significant positive effects on health and lifespan.

As people age, they accumulate damaged cells. When the cells get to a certain level of damage they go through an aging process of their own, called cellular senescence. The cells also release inflammatory factors that tell the immune system to clear those damaged cells. A younger person’s immune system is healthy and is able to clear the damaged cells. But as people age, they aren’t cleared as effectively. Thus they begin to accumulate, cause low level inflammation and release enzymes that can degrade the tissue.

Robbins and fellow researchers found a natural product, called Fisetin, reduces the level of these damaged cells in the body. They found this by treating mice towards the end of life with this compound and see improvement in health and lifespan. The paper, “Fisetin is a senotherapeutic that extends health and lifespan,” was recently published in EBioMedicine.

Continue reading “Researchers discover how to slow aging” »

A new tool using data and AI is hoping to better predict famine and help millions experiencing food insecurity.