Lifeboat Foundation

Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body’s internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function. This discovery offers new avenues for prevention and treatment strategies.

The study, published online today in the journal Science Advances, offers a more comprehensive understanding of how important changes occur in the function and composition of the gut microbiome when the circadian clock is disturbed in the presence of colorectal cancer.

“There is an alarming rise in early-onset colorectal cancer in adults under the age of 50,” said corresponding author Selma Masri, associate professor of biological chemistry. “Circadian misalignment through extended light exposure, late-night meals and other environmental factors could [be] driving these cases. Our study suggests that clock disruption, particularly through lifestyle choices, may play a significant role in gut health and, subsequently, cancer risk.”

Research on Heliconius butterflies illustrates how variations in brain circuits are aligned with their unique foraging behaviors, enhancing their spatial and visual memory.

A tropical butterfly species with uniquely expanded brain structures shows a fascinating mosaic pattern of neural expansion linked to a key cognitive innovation.

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How do plants and fungi communicate with each other? This is what a recent study published in Molecular Cell hopes to address as an international team of researchers investigated the “language” conducted between plants and fungi that enables fungi growth. This study holds the potential to help scientists and farmers better understand how to fight disease-causing fungi by growing crops with greater resilience and adversity.

“As we begin to understand how plants and fungi communicate, we will better understand the complexities of the soil ecosystem, leading to healthier crops and improving our approach to biodiversity,” said Dr. Shelley Lumba, who is an assistant professor in the Department of Cell and Systems Biology at the University of Toronto and a co-author on the study.

For the study, the researchers examined strigolactone (SL), which is a class of plant hormones and signaling molecules responsible for plant development, with the team focusing on how SL influences fungi growth and development by testing SL with yeast. In the end, the researchers found that SL triggered certain genes called “PHO” that are responsible for phosphate metabolism, along with finding that plants release SL when they are low on phosphate, forcing the yeast to alter the amount of phosphate consumes by triggering the protein, Pho84.

Inaction on the water crisis could put more than half of the world’s food production at risk by 2050, experts warned in a major report published Thursday.

While infrared cameras are valuable tools for enhanced vision, food and plant quality control, security, etc, today’s cameras often face significant drawbacks. For instance, they are bulky and power-hungry, requiring cooling systems that limit their functionalities.

More importantly, current semiconductor-based technology used in the cameras only captures a narrow band of the infrared spectrum based on the absorption band of the semiconductor detector. This means that every application would need a separate camera.

“Due to the complications of today’s bulky, power-hungry and expensive infrared imaging technology, we are unlikely to have an infrared camera at home. However, nonlinear frequency conversion, a process that manipulates and translates electromagnetic signals across various frequency regimes, holds a massive potential to revolutionize infrared detection technology,” said Prof Mohsen Ramhami, the leader of Advanced Optics and Photonics Lab, and a UK Research and Innovation Future Leaders Fellow.

Expanding Healthy Human Lifespan for All — Dr. Mehmood Khan, MD — CEO, Hevolution Foundation.

Dr. Mehmood Khan, MD is the Chief Executive Officer of Hevolution Foundation (https://www.hevolution.com/), a first of its kind non-profit organization that funds research through grants and provides investments in biotech to incentivize healthspan science across disciplines and borders for the benefit of all. Established by a Saudi Royal Decree, with its headquarters in Riyadh, with additional international hubs to support the expansion and execute the global mission, it’s vision is to expand healthy human lifespan for the benefit of all humanity.

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Millionaire biohacker Bryan Johnson has shared his anti-aging lunch that can apparently help you live until the age of 120.

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also — in a particular subset of T cells — cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

The findings, published Sept. 20 in the journal Science Immunology, offer a mechanistic understanding for how cells respond to heat and could explain how chronic inflammation contributes to the development of cancer.

The impact of fever temperatures on cells is a relatively understudied area, said Jeff Rathmell, PhD, Cornelius Vanderbilt Professor of Immunobiology and corresponding author of the new study. Most of the existing temperature-related research relates to agriculture and how extreme temperatures impact crops and livestock, he noted. It’s challenging to change the temperature of animal models without causing stress, and cells in the laboratory are generally cultured in incubators that are set at human body temperature: 37 degrees Celsius (98.6 degrees Fahrenheit).

Researchers have long observed that a common family of environmental bacteria, Comamonadacae, grow on plastics littered throughout urban rivers and wastewater systems.

Finding could lead to bioengineering solutions to clean up plastic waste.

A new study finds that a common bacterium can break down plastic for food, opening new possibilities for bacteria-based engineering solutions to help clean up plastic waste. Illustration credit Ludmilla Aristilde/Northwestern University.

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