Archive for the ‘life extension’ category

Jun 1, 2020

Battling Parkinson’s disease

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

Who has heard of mitochondrial medicine?

“We know that increased rates of mtDNA mutation cause premature aging,” said Bruce Hay, Professor of biology and biological engineering at the California Institute of Technology. “This, coupled with the fact that mutant mtDNA accumulates in key tissues such as neurons and muscle that lose function as we age, suggests that if we could reduce the amount of mutant mtDNA, we could slow or reverse important aspects of aging.”

This brings us to the second major development relevant to mitochondria in disease — that genetic technology is now at a point where the targeted removal of the problem mitochondrial genes can become the basis for clinical intervention. This is the implication of research that Hay and colleagues both at Caltech and the University of California at Los Angeles described in a paper published in the journal Nature Communications.

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May 30, 2020

Nanodevices Track Cells From the Inside, Show How They Develop With Time

Posted by in categories: biotech/medical, life extension

For the first time, scientists have added microscopic tracking devices into the interior of cells, giving a peek into how development starts.

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development. This work on one-cell embryos is set to shift our understanding of the mechanisms that underpin cellular behavior in general, and may ultimately provide insights into what goes wrong in aging and disease. The research, led by Professor Tony Perry from the Department of Biology and Biochemistry at the University of Bath, involved injecting a silicon-based nanodevice together with sperm into the egg cell of a mouse. The result was a healthy, fertilized egg containing a tracking device. The tiny devices are a little like spiders, complete with eight highly flexible ‘legs’.

May 30, 2020

Bill Faloon — If Nothing Else Kills Us, Aging Will (Longevity #005)

Posted by in categories: biotech/medical, computing, food, life extension, neuroscience, quantum physics

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May 30, 2020

Disrupting death: Could we really live forever in digital form?

Posted by in categories: holograms, life extension, robotics/AI, virtual reality

We’re getting closer to technologies that let us exist forever in some way — using data to power our existence in VR, robots, chatbots and holograms. Should we do it?

May 29, 2020

First Ever Anti-Ageing Gene Discovered in a Secluded Amish Family

Posted by in categories: biotech/medical, genetics, life extension

Circa 2017 :3

For the first time, scientists have found a genetic mutation that appears to offer a measure of protection against some of the biological effects of ageing.

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May 29, 2020

BRIAN KENNEDY — Reversing Human Aging (#0004)

Posted by in categories: biotech/medical, genetics, life extension, robotics/AI

Sirtuins, telomeres, A.I. experiment with vitamin A and personalized medicine, a bit of everything here.

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May 26, 2020

Solving the space junk problem

Posted by in categories: life extension, satellites

Space is getting crowded. Aging satellites and space debris crowd low-Earth orbit, and launching new satellites adds to the collision risk. The most effective way to solve the space junk problem, according to a new study, is not to capture debris or deorbit old satellites: it’s an international agreement to charge operators “orbital-use fees” for every satellite put into orbit.

May 25, 2020

Dr. Michael R. Rose presents “Biological Immortality is REAL”

Posted by in categories: biological, education, evolution, life extension

Dr. Michael R. Rose is Professor at Department of Ecology and Evolutionary Biology at University Of California, Irvine. His main area of work has been the evolution of aging.
“Our task is to make nature, the blind force of nature, into an instrument of universal resuscitation and to become a union of immortal beings.“
- Nikolai F. Fedorov

We hold faith in the technologies & discoveries of humanity to END AGING and Defeat involuntary Death within our lifetime.

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May 23, 2020

DNA-repairing enzyme reverses age-related cognitive decline

Posted by in categories: biotech/medical, life extension, neuroscience

DNA damage is common to our cells, but when we’re young our bodies can fix it pretty easily. Unfortunately we lose that ability over time, leading to many of the symptoms of aging that we know all too well. A new study from MIT has found that reactivating a certain enzyme improves repair of DNA damage in neurons, which helps Alzheimer’s patients and others with cognitive decline.

Previous studies by the team have shown that an enzyme called HDAC1 seems to be involved in DNA repair in neurons. For the new study, the researchers examined what happens when HDAC1 doesn’t do its job.

The team engineered mice to be deficient in HDAC1, and monitored their health compared to normal mice. Things looked good during the animals’ youth – there were no differences in DNA damage or behavior between the two groups. But as they aged, the decline became clear.

May 23, 2020

Nano Comes to Life: How Nanotechnology Is Transforming Medicine and the Future of Biology

Posted by in categories: 3D printing, biotech/medical, life extension, nanotechnology, neuroscience, quantum physics

If you’re interested in superlongevity and superintelligence, then I have a book to recommend., by Sonia Contera, is a book about the intersection of biotech and nanotech. Interesting and well written for the layman, the book covers some of the latest developments in nanotechnology as it applies to biological matters. Although there are many topics, I was primarily interested in the DNA nanobots, DNA origami, and the protein nanotechnology sections. My interest is piqued in these arenas due to my expectation that DNA nanobots and protein nanobots, as well as complex self-assembled custom nanostructures, are going to be key to some of the longevity technologies and some of the possible substrates for mind uploading that are key to superlongevity and superintelligence. There are also sections in the book on 3D bioprinted organs — progress and possibilities, as well as difficulties.

There is even a section that clearly was written specifically to address a discussion that has engaged my friends, Dinorah Delfin and Dan Faggella. The title is:


Now, some might be tempted to consider that particular combination to be “woo woo”, however, please keep in mind the author’s credentials. Sonia Contera is a professor of biological physics in the Department of Physics at the University of Oxford.

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