Lifeboat Foundation

Project for Awesome (P4A) 2018 is finally here, and you can help us to win much-needed funds at no cost to you by voting for the videos supporting our charity.

Every year, a number of charities are chosen through voting, and they each receive a sum of money based on what the fundraiser at P4A has raised. In the past, charities have received around $25,000 each, which is a considerable sum, especially for a small non-profit org such as LEAF.

Continue reading “Support the Drive to End Age-Related Diseases During Project for Awesome” »

Continue reading “Regenerage — SMX Radio — The Net of Regenerative Medicine — Bioquark” »

Today, we want to highlight results from human trials in which stem cell transplants have been shown to reduce age-related frailty.

Age-related frailty and stem cell transplants

Currently, there are no specific approved therapies to address age-related frailty, which can cause elderly people to suffer potentially fatal falls and injuries. There has been considerable interest in stem cell therapies to combat frailty in recent years, and the results we will discuss today are from one of the more advanced human clinical trials exploring mesenchymal stem cell (MSC) transplants [1].

Continue reading “Human Stem Cell Trial Successful Against Age-Related Frailty” »

And his team at Yale-NUS have recently completed a detailed set of studies looking at eleven of the most promising anti-aging single drugs, using nematode worms (C. elegans) as their model organism.

Drug synergy found to increase lifespan in worms

Even though testing the effects of single drugs on health and longevity in various organisms is challenging by itself, and testing multiple drugs and their synergistic effects can be a logistical and statistical nightmare, they found some surprising results, including up to a 96 percent increase in lifespan [1]. As they conclude in their new paper:

Continue reading “Jan Gruber – Looking at synergistic effects in longevity therapies” »

The Fourth Eurosymposium on Healthy Ageing (EHA) was held in Brussels on November 8–10, 2018, and we had the opportunity to give talks about aging, advocacy, and engaging new audiences.

The EHA is a conference hosted every two years by Heales, and it sees like-minded people from the research and advocacy community come together to share knowledge and listen to talks from various researchers and other experts in the field. We were very pleased to be invited to give two presentations during the conference and share our knowledge and experience with the audience there.

Continue reading “LEAF at the Eurosymposium on Healthy Ageing” »

Questions have been raised recently regarding Jeanne Calment’s record as the oldest recorded human.

If you open an article dedicated to supercentenarians, it is very likely that at its very beginning, you will see the name of Jeanne Calment, the oldest known person in the world, who is believed to have lived for up to 122 years. Jeanne is not merely a unique phenomenon from the point of view of statistics; over the years, she became a symbol of extraordinary human capacities.

For a person who sticks to a healthy lifestyle or even engages in biohacking in order to live longer, Jeanne’s record is a teasing goal to achieve and surpass; however, to the researchers of aging, this extremely rare event is rather a reason for curiosity – and skepticism.

Continue reading “Valery Novoselov: Investigating Jeanne Calment’s Longevity Record” »

‘Tis the season to be jolly, friends of healthy longevity! Time to dim the lights, gather around a crackling fireplace, cuddle up into a warm blanket, and recap the rejuvenation news of last November.

February 4th, 2019 sees the launch of the Longevity Leaders Conference in St Paul’s, London, which promises to be an interesting event on the conference calendar.

The conference aims to cover both the science of aging research and the business side of the industry, in a similar manner to our own annual conference, Ending Age-Related Diseases, which we host in New York. Mixing the worlds of science and business is a good idea as we move ever closer to the first true rejuvenation technologies arriving.

It is essential to begin forging bonds between the researchers who are making the science a reality and the investors and angels who have the knowledge and expertise to take the science to market.

Continue reading “The Longevity Leaders Conference” »

Yang N, Sen P,. The senescent cell epigenome. Aging (Albany NY). 2018; 10:3590–3609. https://doi.org/10.18632/aging.

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