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Efficacy and Safety of VMAT2 Inhibitors in the Treatment of Huntington DiseaseA Meta-Analysis of Randomized Clinical Trials

In patients with Huntington disease, vesicular monoamine transporter 2 inhibitors (VMAT2is) treatment improved chorea without significant changes in adverse effects or depressive symptoms.


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Influence of Decreased Kidney Function on Plasma Biomarkers of Neurodegenerative Disorders in Routine Care: Confirmation of the Interest of Ratios

This study found that impaired kidney function was linked to increased plasma cerebral amyloidosis biomarkers, but ratio-based measures showed stable sensitivity and specificity for detecting cerebral amyloidosis across all eGFR groups.


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Bitwarden CLI Compromised in Ongoing Checkmarx Supply Chain Campaign

When reached for comment, Bitwarden confirmed the incident and said it stemmed from the compromise of its npm distribution mechanism following the Checkmarx supply chain attack, but emphasized that no end-user data was accessed as part of the attack. The entire statement shared with The Hacker News is reproduced verbatim below

The Bitwarden security team identified and contained a malicious package that was briefly distributed through the npm delivery path for @bitwarden/cli@2026.4.0 between 5:57 PM and 7:30 PM (ET) on April 22, 2026, in connection with a broader Checkmarx supply chain incident.

The investigation found no evidence that end user vault data was accessed or at risk, or that production data or production systems were compromised. Once the issue was detected, compromised access was revoked, the malicious npm release was deprecated, and remediation steps were initiated immediately.

Microsoft releases emergency patches for critical ASP.NET flaw

Microsoft has released out-of-band (OOB) security updates to patch a critical ASP.NET Core privilege escalation vulnerability.

The security flaw (tracked as CVE-2026–40372) was found in the ASP.NET Core Data Protection cryptographic APIs, and it could allow unauthenticated attackers to gain SYSTEM privileges on affected devices by forging authentication cookies.

Microsoft discovered the flaw following user reports that decryption was failing in their applications after installing the. NET 10.0.6 update release during this month’s Patch Tuesday.

Hackers exploit file upload bug in Breeze Cache WordPress plugin

Hackers are actively exploiting a critical vulnerability in the Breeze Cache plugin for WordPress that allows uploading arbitrary files on the server without authentication.

The security issue is tracked as CVE-2026–3844 and has been leveraged in more than 170 exploitation attempts by the Wordfence security solution for the WordPress ecosystem.

The Breeze Cache WordPress caching plugin from Cloudways has more than 400,000 active installations and is designed to improve performance and loading speed by reducing page load frequency through caching, file optimization, and database cleanup.

Parkinson Disease Pathogenic VariantsCross-Ancestry Analysis and Microarray Data Validation

Parkinson disease pathogenic variants: cross-ancestry analysis and microarray data validation.


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Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

“Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via microbial N-bc2S1P synthesis on neonatal skin” http://spkl.io/6184A4yYI

CellHostandMicrobe.


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