Using DANGEROUS MIX autoimmune plants with constitutively active NLRs, Hu et al. dissect growth-defense trade-offs. Two major transcriptional modules, representing growth and defense, show a strong inverse correlation and are governed by ADR1 helper NLRs. ADR1s maintain this balance largely through effects on transcription and chromatin accessibility in both modules.

Dubbed Heretic2R, the sourceport introduces a bunch of new technical features to the elf wizard Corvus’ second adventure. For starters, it adds widescreen support with automatic HUD scaling, and unlocks the framerate to a theoretical maximum of 1,000 FPS.

On top of this, Heretic 2R ensures that in-game special effects update at the appropriate rendering framerate, improves map loading times, and makes “lots of cosmetic improvements” so that “the game plays as you remember it, not as it actually played”. Which sounds very remaster-y to me.

Wang et al. show that lipocalin-2 suppresses iron-dependent cell death in glioblastoma. Targeting multiple members in this pathway activates iron-dependent cell death, increases survival in mouse models, and demonstrates a potential therapy for glioblastoma.

Chemists made a photocatalytic discovery when their control reaction led to an unexpected product

Honeybees fly consistent, landmark-guided routes with remarkable precision, revealing better navigation than their waggle dance suggests.

Zhen Zhuang et al. identify MERS-CoV-specific T cell epitope repertoires in C57BL/6 and BALB/c mice and demonstrate that ORF4b208-specific CD4+ and ORF5167-specific CD8+ T cells are polyfunctional effectors and protective in MERS-CoV infection.

A new RNA-based therapy aims to address one of cardiology’s most persistent challenges: the heart’s inability to regenerate after injury.

(Cell Reports 32, 108196; September 29, 2020)

As this paper was originally published on September 29, 2020, Figure 3C showed similar imagery across western blot analyses for αTubulin and pAkt⁴⁷³. This error was caused by an inadvertent swap of two loading control panels of αTubulin and Akt that appeared during figure assembly. The corrected figure can be seen below.

The error and correction thereof do not affect the results or conclusions of the study. The authors apologize for any confusion caused.

What if everything you knew about The Matrix was a lie? This dark theory suggests that Neo is not the One, but a \.

Atheist philosopher Graham Oppy is asked what it would take for him to believe in God. Watch his debate with Christian convert Guillaume Bignon here: https://www.thebigconversation.show/v…