Ubisoft’s Rainbow Six Siege (R6) suffered a breach that allowed hackers to abuse internal systems to ban and unban players, manipulate in-game moderation feeds, and grant massive amounts of in-game currency and cosmetic items to accounts worldwide.

Li et al. report that ID1 sustains STING activation and innate immunity by blocking PRMT5-STING binding, thereby preventing PRMT5-mediated methylation at Arg281 of STING. The PRMT5 inhibitor EPZ015666 enhances STING activation by suppressing PRMT5, providing a therapeutic candidate for antiviral treatment.

In the Middle Ages, a plague killed a third of Europe’s population. Fleas carried the plague bacterium, Yersinia pestis, transmitting the Black Death from infected rats to millions of people.

Toxic spongiform: leukoencephalopathy with chronic fentanyl inhalation.

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Gilligan and his crew gave us an inside look at how they built ‘Pluribus’ into a happy-ish apocalypse.

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