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Adobe Will Pay $75 Million to Settle Lawsuit over Its Subscriptions

“Adobe fails to adequately disclose to consumers that by signing up for the ‘Annual, Paid Monthly’ subscription plan, they are agreeing to a year-long commitment and a hefty early termination fee that can amount to hundreds of dollars,” the complaint read.

This lawsuit is finally closed, with Adobe agreeing to pay $75 million worth of services for free to the affected customers and an extra $75 million to the Department of Justice.

However, the company doesn’t agree with the accusations made against it.

Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement

Astrocyte-microglia crosstalk in thalamocortical synapse refinement.

Both microglia and astrocytes play crucial role in synapse refinement during development but it is not clear how they communicate to balance synapse formation and elimination.

The researchers show that astrocytes instruct this process through the secreted synaptogenic protein Hevin/Sparcl1.

The proteolytically generated C-terminal of Hevin signals to microglia via TLR4, triggering a pro-phagocytic state that promotes refinement of thalamocortical synapses in the developing visual cortex. sciencenewshighlights ScienceMission https://sciencemission.com/Hevin-and-Toll-like-receptor


Microglia are key drivers of synapse refinement during development. Ramirez et al. show that astrocytes instruct this process through the secreted synaptogenic protein Hevin/Sparcl1. The proteolytically generated C-terminal of Hevin signals to microglia via TLR4, triggering a pro-phagocytic state that promotes refinement of thalamocortical synapses in the developing visual cortex.

Evolutionary causes and consequences of gene duplication

Gene duplication is a key evolutionary mechanism, as initially redundant paralogues diverge over time. The authors review how adaptive and non-adaptive forces influence the evolutionary fates of gene duplicates, highlighting the importance of function–fitness relationships and gene expression dynamics.

NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma

(Cell Reports 41, 111623; November 8, 2022)

As this paper was originally published, Figure 5C included a sample that was inadvertently shown twice. Because this paper was published in 2022, the paper itself cannot be updated, but the revised Figure 5C can be seen below. The authors apologize for any confusion that may have occurred due to the original figure. Dr. Atfi can be reached at azeddine.atfi@gmail.com in addition to the correspondence provided above.

Electroacupuncture suppresses premature ventricular complexes occurring post-myocardial infarction through corticothalamic circuit

(Cell Reports 45, 116734; January 27, 2026)

When this paper was published on December 18, 2025, Figure S2 inadvertently omitted panel C. The article has since been updated online with the correct, complete figure. For readers’ convenience, both the original and corrected figures can be seen below. The authors apologize for the error.

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