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Time is a Processing Delay

I show how the time dilation derived in special relativity by assuming an abstract concept of malleable time, can be derived in a more mechanistic manner by assuming that the cosmos is like a simulation \& time is a processing delay.

I had this idea while playing minecraft with my son — every time I approached a large villager-town the PC slowed down and I thought \.

Self-Amplifying RNA: Advantages and Challenges of a Versatile Platform for Vaccine Development

Self-amplifying RNA is synthetic nucleic acid engineered to replicate within cells without generating viral particles. Derived from alphavirus genomes, saRNA retains the non-structural elements essential for replication while replacing the structural elements with an antigen of interest. By enabling efficient intracellular amplification, saRNA offers a promising alternative to conventional mRNA vaccines, enhancing antigen expression while requiring lower doses. However, this advantage comes with challenges. In this review, we highlight the key limitations of saRNA technology and explore potential strategies to overcome them. By identifying these challenges, we aim to provide insights that can guide the future design of saRNA-based therapeutics, extending their potential beyond vaccine applications.

Cachexia-induced alterations of miR-27a-3p drive cell-type specific effects in FAPs and tumor cells that coincide with muscle wasting

Self-amplifying RNA is synthetic nucleic acid engineered to replicate within cells without generating viral particles. Derived from alphavirus genomes, saRNA retains the non-structural elements essential for replication while replacing the structural elements with an antigen of interest. By enabling efficient intracellular amplification, saRNA offers a promising alternative to conventional mRNA vaccines, enhancing antigen expression while requiring lower doses. However, this advantage comes with challenges. In this review, we highlight the key limitations of saRNA technology and explore potential strategies to overcome them. By identifying these challenges, we aim to provide insights that can guide the future design of saRNA-based therapeutics, extending their potential beyond vaccine applications.

This Will Replace Silicon Chips

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#AnkerTech.

Timestamps:
00:00 — New Semiconductor.
08:44 — Computers of The Future.

My Podcast on Apple: https://podcasts.apple.com/at/podcast
My Podcast on Spotify: https://open.spotify.com/show/3drr7A8… Let’s connect on LinkedIn: / anastasiintech Newsletter: https://anastasiintech.substack.com Instagram: / anastasi.in.tech Patreon: / anastasiintech.

Let’s connect on LinkedIn: / anastasiintech.
Newsletter: https://anastasiintech.substack.com.
Instagram: / anastasi.in.tech.
Patreon: / anastasiintech.

Watch this spider crawl like an ant to avoid being eaten

Unlike some other spiders that camouflage themselves with drab colors and sticklike appendages, the jumping spider Siler collingwoodi disguises itself by the way it moves. The bright blue and orange arachnid—a pea-size animal native to China and Japan—crawls like an ant, according to a new study.

In a side-by-side comparison, researchers found that S. collingwoodi spiders copied the movements of multiple spikey, aggressive species of ants. The spiders walked at a similar pace, bobbed their abdomens like the ants did, and elevated their first pair of legs when they walked, imitating antennae.

Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment

Nasal commensal viruses may worsen allergic rhinitis by activating type I IFN-linked neutrophils and NET formation. Ribavirin reduced nasal viral abundance and improved symptoms in mice and in a small phase 2 trial.

PARP1-specific inhibitor displays PARP1-detrapping activity

(Cell Reports 45, 117350; May 26, 2026)

In the originally published version of this article, there was an error with Figure 3H that occurred during the final preparation of the manuscript, where some of the cellular images were displayed as black panels. The figure has been replaced with a corrected Figure 3H where the cellular images are now visible.

The authors regret this error.

New technology helps reveal how the heart generates cells with regenerative potential

Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes—the cells responsible for heart contraction.

The study, published in Genome Biology, shows that the transcription factor Myc, used in regenerative strategies, alters protein expression in each cell differently, generating a subpopulation of cardiomyocytes with regenerative potential.

According to study leaders Miguel Torres and Jesús Vázquez, the findings provide key insights into the mechanism of action of Myc at the level of individual cardiomyocytes and offer new opportunities for the development of future regenerative therapies.

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