Melatonin reduced infection-related inflammation in human fetal membranes in an ex vivo model. The study suggests that this effect works partly through melatonin receptors and by suppressing the TLR4/MyD88/NF-κB pathway.

Nasal commensal viruses may worsen allergic rhinitis by activating type I IFN-linked neutrophils and NET formation. Ribavirin reduced nasal viral abundance and improved symptoms in mice and in a small phase 2 trial.

(Cell Reports 45, 117350; May 26, 2026)

In the originally published version of this article, there was an error with Figure 3H that occurred during the final preparation of the manuscript, where some of the cellular images were displayed as black panels. The figure has been replaced with a corrected Figure 3H where the cellular images are now visible.

The authors regret this error.

Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes—the cells responsible for heart contraction.

The study, published in Genome Biology, shows that the transcription factor Myc, used in regenerative strategies, alters protein expression in each cell differently, generating a subpopulation of cardiomyocytes with regenerative potential.

According to study leaders Miguel Torres and Jesús Vázquez, the findings provide key insights into the mechanism of action of Myc at the level of individual cardiomyocytes and offer new opportunities for the development of future regenerative therapies.

Julie Elie worked out how zebra finches announce who they are, what they are doing and use individual signatures

Fossils tucked away in a museum drawer and identified merely as “feline” are actually from a very ancient and enigmatic saber-toothed cat that inhabited North America more than 5 million years ago. Newly identified by a UC Berkeley paleontologist, the nearly complete skull helps clarify how these large-fanged felines evolved over millennia before going extinct about 10,000 years ago.

One clear takeaway is that these cats started out with smaller fangs—the upper canines—but evolved increasingly longer ones that may have led to their ultimate demise. California’s state fossil, Smilodon fatalis (originally called S. californicus), was the culmination of that trend. It had some of the largest upper canines of any saber-toothed animal—up to 7 inches (18 centimeters) long—but was the last saber-toothed animal to survive.

According to Berkeley postdoctoral fellow Narimane Chatar, the cranium, teeth and lower jaw (or mandible) she stumbled upon in the American Museum of Natural History in New York are from the species Adelphailurus kansensis, originally discovered in Kansas and known only from jaw fragments and teeth. Now, with the first complete skull of the cat, she has been able to tentatively place the animal within the family tree of saber-toothed carnivores and contrast it with the most recognizable saber-toothed cat, Smilodon, which ranged throughout the Americas.

It’s important to mention that Sanger had started the WikiProject Intellectual Diversity project to reinforce Wikipedia’s original purpose, which was to provide knowledge neutrally and transparently, especially because, in later years, some people have thought that the site leans toward left-wing ideas.

Sanger said that he feels more sorry for Wikipedia because he was trying to fix the site, but it was overrun by bias and censorship. He wrote about the whole thing for The Free Press, but you can read it only if you are willing to pay the subscription fee.

Quick Read: https://www.marktechpost.com/2023/10/17/meet-universal-simul…-modeling/

Paper: https://arxiv.org/abs/2310.06114

Project: https://universal-simulator.github.io/unisim/.

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