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The Darkest Science Fiction Stories Ever

This video is a compilation of some of the darkest science fiction stories I’ve covered on this channel. If you’ve been around for a while then you might have seen some of them, but some you may have not!

01:00 — The Killing Star.
14:10 — Nightfall.
31:40 — Annihilation.
44:29 — Metamorphosis of Prime Intellect.
01:01:51 — There is No Antimemetics Division.
01:21:52 — The Word for World Is Forest.

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🎵 Music: / @jamezdahlmusic.

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Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation

Postlmayr et al. show that ALK and ROS1 fusions identified in IHG drive increased STAT3 and SHP2 signaling, revealed by multi-omic integrative analyses and validated in vitro and in vivo. Distinct microtubule-binding fusion partners further promote a hypermotile, invasion-prone phenotype, highlighting the role of fusion partners in specific tumorigenic behavior.

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