In a cohort study comparing high-risk definitions for smoldering multiple myeloma (#SMM), the AQUILA trial criteria was assessed against the 2/20/20 risk model.

The AQUILA criteria classified approximately 3 times more individuals as high-risk versus the 2/20/20 model, but included a substantial group with lower progression risk.

The 2/20/20 model more precisely identified a smaller group of individuals with higher risk of progression, supporting its use to target early intervention for those most likely to benefit.

This cohort study compares the AQUILA trial inclusion criteria and the 2/20/20 risk stratification model definitions for identifying individuals with smoldering multiple myeloma at high risk of progression.

RetroRender will bring back the golden age of pixels in Unity.

Theorists have identified a phase that could facilitate the switching of a crystal between its right-handed and left-handed versions.

Apple fixes CVE-2026–28950 in iOS 26.4.2 after deleted notifications were retained, mitigating forensic data exposure.

The current model of necroptosis assumes that MLKL’s N-terminal cytotoxic domain is unleashed from autoinhibition concurrent with phosphorylation by RIPK3. Here, Pan and Abbott show that inhibition of MLKL’s N terminus abolishes phosphorylation by RIPK3 whereas removal or relieving autoinhibition between the N-terminal and intermediate domains promotes its phosphorylation.

A new model reveals that two very different laser pulse behaviors are fundamentally connected.

Malicious KICS Docker tags and VS Code versions 1.17.0, 1.19.0 enabled data exfiltration, risking exposed infrastructure secrets.

Self-propagating npm worm steals tokens via postinstall hooks, impacting six packages and expanding supply chain attacks.