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Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit

Using multicellular patch-clamp recording, the authors show that the hippocampal CA3 autoassociative network undergoes pruning of CA3–CA3 synapses and downregulation of synaptic efficacy during postnatal development, suggesting a double transformation of coding properties and memory functions.

Apple blocked over $11 billion in App Store fraud in 6 years

Apple revealed that it blocked over $11 billion in fraudulent App Store transactions over the last six years, more than $2.2 billion in potentially fraudulent App Store transactions in 2025 alone.

In a Wednesday press release, the tech giant said it rejected over 2 million problematic app submissions last year and blocked more than 1.1 billion fraudulent account creations.

Apple also terminated 193,000 developer accounts due to fraud concerns, rejected more than 138,000 developer enrollments, and deactivated an additional 40.4 million customer accounts suspected of fraud and abuse.

The Unambigous Alien Probe and the Von Neumann Cloud

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Music:

Cylinder Five by Chris Zabriskie is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/.https://chriszabriskie.com/cylinders/ Intermission in D by Miguel Johnson https://migueljohnson.bandcamp.com/

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