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How bacteria use acetyl coenzyme as a building block in the formation of cells

Researchers at the University of Greifswald have discovered a new mechanism by which bacteria such as Bacillus subtilis can regulate the production of the central metabolic molecule acetyl coenzyme A (Acetyl-CoA). Acetyl-CoA, also known as activated acetic acid, is crucial in the production of nutrients, i.e., proteins, carbohydrates and lipids, and thus plays a key role in the metabolism of all cells.

Until now, it was unclear how bacteria coordinate the production and decomposition of activated acetic acid using this pathway. New findings published in the journal Nature Communications have now shown that Bacillus subtilis uses a special regulatory mechanism to coordinate both processes.

When cells are supplied with an abundance of nutrients, they are forced to decide whether to gain energy or create building blocks for growth. At the heart of this decision-making process is acetyl coenzyme A, which links the decomposition of nutrients with the synthesis of proteins, carbohydrates and lipids, thereby acting as a central hub for the entire metabolism during cell formation.

ShinyHunters Exploits Oracle PeopleSoft Zero-Day (CVE-2026–35273) to Breach Universities

The ShinyHunters extortion crew exploited an unpatched flaw in Oracle PeopleSoft to break into enterprise systems, steal data, and demand payment to keep it private. The campaign hit universities hardest.

Google’s Mandiant attributes it to the group it tracks as UNC6240, and dates the activity between May 27 and June 9. Oracle did not publish its advisory until June 10, so the bug was a zero-day the entire time.

The flaw, CVE-2026–35273, is a remote code execution bug in PeopleSoft Enterprise PeopleTools rated 9.8 out of 10. It needs no login and no user interaction, just network access over HTTP, to take over the server. If you run PeopleSoft with the Environment Management Hub reachable from outside, that is your exposure, and the immediate move is to lock those endpoints down.

I watched the new Halo remake gameplay, then replayed the original to nitpick the differences

I’m going into Campaign Evolved with an open mind—expecting different, but not necessarily better. Halo Studios’ official playthrough of mission five, Assault on the Control Room, is so far confirming that impression. I watched the 28-minute video in full and then played the original mission through the MCC to refresh my memory. What follows are some notable differences and observations:

“These lights seem to be responding to our proximity and guiding us to the exit,” a new Cortana voice line says as Chief enters the first of many hexagonal control rooms. It could be a little confusing to find your way around these rooms in the originals, but l always found the flashing white arrows on the ground pointing forward to be sufficient visual guidance. Now, Cortana barks that tip into your ear so you can’t possibly miss it.

Not that you actually need to look for arrows on the ground when Campaign Evolved has added HUD waypoints that are visible at all times. This is one of several ways that Halo Studios’ is applying a modern hand-holdy lens to Combat Evolved.

People are not as dishonest as we expect them to be, finds new study

According to a Pew Research report, Americans trust one another less than they did a few decades ago. Social trust is shaped largely by personal experiences of navigating the world, as well as by how strongly people believe others are likely to act honestly or dishonestly in everyday life.

Future AI chips could be built on glass

The idea is to use glass as the substrate, or layer, on which multiple silicon chips are connected. This form of “packaging” is an increasingly popular way to build computing hardware, because it lets engineers combine specialized chips designed for specific functions into a single system. But it presents challenges, including the fact that hardworking chips can run so hot they physically warp the substrate they’re built on. This can lead to misaligned components and may reduce how efficiently the chips can be cooled, leading to damage or premature failure.

“As AI workloads surge and package sizes expand, the industry is confronting very real mechanical constraints that impact the trajectory of high-performance computing,” says Deepak Kulkarni, a senior fellow at the chip design company Advanced Micro Devices (AMD). “One of the most fundamental is warpage.”

That’s where glass comes in. It can handle the added heat better than existing substrates, and it will let engineers keep shrinking chip packages—which will make them faster and more energy efficient. It “unlocks the ability to keep scaling package footprints without hitting a mechanical wall,” says Kulkarni.

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