Toggle light / dark theme

Researchers Create a New Antivenom That Can Combat Bites From 17 Snake Species, Trials in Mice Suggest

The study points to a few other benefits: Modern antivenoms don’t address the tissue damage that can be wrought by snake venom, but the nanobodies in the new product seemed to decrease tissue injury in mice, even with delayed treatment. And since nanobodies are less likely to cause serious immune reactions, per the statement, clinicians could theoretically administer the new antivenom before the appearance of clear symptoms, instead of waiting in an attempt to avoid severe side effects.

Still, because the experiments were performed on lab animals, not humans, the new antivenom is nowhere near commercial availability—first, the concept must be proven in human subjects. As such, the team is working on improving the antivenom and securing more funding.

“We have both a moral and global responsibility to contribute to solving this problem,” Laustsen-Kiel says in the statement. “Our antivenom has the potential to fundamentally change how snakebites are treated around the world.”

As brain organoids grow increasingly complex, leading scientists and bioethicists call for global oversight

In an effort to address these ethical grey areas, 17 leading scientists and bioethicists from five countries are urging the establishment of an international oversight body to monitor advances in the rapidly expanding field of human neural organoids and to provide ethical and policy guidance as the science continues to evolve. The call to action, published Thursday in Science, comes as U.S. government agencies are making new investments in organoid science aimed at accelerating drug discovery and reducing reliance on animal models of disease.

In September, the National Institutes of Health announced $87 million in initial contracts to establish a new center dedicated to standardizing organoid research. The move followed an earlier pledge by both the NIH and the Food and Drug Administration to reduce, and possibly replace, testing on mice, primates, and other animals with other methods — including organoids and organ-on-a-chip technologies — for developing certain medicines.

Government promotion of human stem cell models more broadly will only increase the recruitment of new researchers into the field of neural organoids, which has seen an explosion from a few dozen labs a decade ago to hundreds around the world now, said Sergiu Pasca, a pioneering neuroscientist and stem cell biologist at Stanford University who co-authored the Science commentary.

We doubled human lifespans in the last 200 years. Can we do it again? | Andrew Steele

“Over the last 10 or 15 years, scientists have really started to understand the fundamental underlying biology of the aging process. And they broke this down into 12 hallmarks of aging.”

Up next, Why 2025 is the single most pivotal year in our lifetime | Peter Leyden ► • Why 2025 is the single most pivotal year i…

We track age by the number of birthdays we’ve had, but scientists are arguing that our cells tell a different, more truthful story. Our biological age reveals how our bodies are actually aging, from our muscle strength to the condition of our DNA.

The gap between these two numbers may hold the key to treating aging – which could help save 100,000 lives per day and win us $38 trillion dollars.

00:00 Rethinking longevity.
01:27 Understanding aging.
02:58 Biological age and epigenetics.
04:29 New frontiers in longevity science.
08:04 Future possibilities and ethical questions.
10:24 The moral debate around living longer.

The Cyborg Child: SCP-191 and the Ethics of Human Evolution

What happens when the pursuit of perfection forgets compassion?
SCP-191, known as The Cyborg Child, is one of the most haunting examples of speculative bioengineering ever documented. This essay examines the anatomy, psychology, and philosophy of a child transformed into a machine — a being caught between humanity and technology.

In this episode, we explore:

How cybernetic modification redefines the human body.

The science behind hybrid consciousness and neural integration.

The moral cost of evolution without empathy.

What SCP-191 reveals about the posthuman future.

HUMAN Stem Cells Have Reversed Age In Monkey’s with ZERO Side Effects

Age Reversal in Primates has been achieved. We have it now.

Anti-aging gene therapy, stem cell rejuvenation, and FOXO3 longevity research take center stage in this episode of Longevity Science News with Emmett Short. This groundbreaking study out of Beijing shows that gene-edited human stem cells—specifically FOXO3-enhanced senescence-resistant mesenchymal progenitor cells (SRCs)—can reverse biological aging in elderly monkeys, restoring youthful brain structure, bone density, immune strength, and even ovarian function. By upgrading the FOXO3 longevity gene, scientists created stem cells that resist cellular senescence, DNA damage, and oxidative stress, effectively making the monkeys younger from the inside out. MRI scans revealed increased cortical thickness and improved memory-related connectivity, while biological age clocks showed a 3–5 year reversal across 54% of tissues—equivalent to 9–15 years of human rejuvenation. Emmett explains how these anti-aging stem cells, epigenetic resets, and exosome-based rejuvenation pathways could revolutionize regenerative medicine, longevity biotech, and future human trials. He also explores the costs, ethics, and long-term implications of turning back time at the cellular level. If you’re passionate about biohacking, gene editing, lifespan extension, or the future of anti-aging science, this is the video for you.

HUME BODY ANALYZER:
Use Code: LONGEVITY for up to 50% OFF
https://humehealth.com//discount/LONGEVITY?redirect=/pages/h…=LONGEVITY

Watch next: Artificial Blood: The SciFi Anti-Aging Tech That’s Now in Human Trials.
https://www.youtube.com/watch?v=3xz1lcGdQPc.

If you’re into the cutting edge of anti-aging science, subscribe and share with someone who wants to live longer, healthier, and stronger.

⏱️ Chapters:

Karl J. Friston

Professors Karl Friston & Mark Solms, pioneers in the fields of neuroscience, psychology, and theoretical biology, delve into the frontiers of consciousness: “Can We Engineer Artificial Consciousness?”. From mimicry to qualia, this historic conversation tackles whether artificial consciousness is achievable — and how. Essential viewing/listening for anyone interested in the mind, AI ethics, and the future of sentience. Subscribe to the channel for more profound discussions!

Professor Karl Friston is one of the most highly cited living neuroscientists in history. He is Professor of Neuroscience at University College London and holds Honorary Doctorates from the University of Zurich, University of York and Radboud University. He is the world expert on brain imaging, neuroscience, and theoretical neurobiology, and pioneers the Free-Energy Principle for action and perception, with well-over 300,000 citations. Friston was elected a Fellow of the Academy of Medical Sciences (1999). In 2000 he was President of the international Organization of Human Brain Mapping. He was elected a Fellow of the Royal Society in 2006. He became a Fellow of the Royal Society of Biology in 2012 and was elected as a member of EMBO (excellence in the life sciences) in 2014 and the Academia Europaea in (2015).

Professor Mark Solms is director of Neuropsychology in the Neuroscience Institute of the University of Cape Town and Groote Schuur Hospital (Departments of Psychology and Neurology), an Honorary Lecturer in Neurosurgery at the Royal London Hospital School of Medicine, an Honorary Fellow of the American College of Psychiatrists, and the President of the South African Psychoanalytical Association. He is also Research Chair of the International Psychoanalytical Association (since 2013). He founded the International Neuropsychoanalysis Society in 2000 and he was a Founding Editor (with Ed Nersessian) of the journal Neuropsychoanalysis. He is Director of the Arnold Pfeffer Center for Neuropsychoanalysis at the New York Psychoanalytic Institute. He is also Director of the Neuropsychoanalysis Foundation in New York, a Trustee of the Neuropsychoanalysis Fund in London, and Director of the Neuropsychoanalysis Trust in Cape Town.

TIMESTAMPS:
0:00 — Introduction.
0:45 — Defining Consciousness & Intelligence.
8:20 — Minimizing Free Energy + Maximizing Affective States.
9:07 — Knowing if Something is Conscious.
13:40 — Mimicry & Zombies.
17:13 — Homology in Consciousness Inference.
21:27 — Functional Criteria for Consciousness.
25:10 — Structure vs Function Debate.
29:35 — Mortal Computation & Substrate.
35:33 — Biological Naturalism vs Functionalism.
42:42 — Functional Architectures & Independence.
48:34 — Is Artificial Consciousness Possible?
55:12 — Reportability as Empirical Criterion.
57:28 — Feeling as Empirical Consciousness.
59:40 — Mechanistic Basis of Feeling.
1:06:24 — Constraints that Shape Us.
1:12:24 — Actively Building Artificial Consciousness (Mark’s current project)
1:24:51 — Hedonic Place Preference Test & Ethics.
1:30:51 — Conclusion.

EPISODE LINKS:
- Karl’s Round 1: https://youtu.be/Kb5X8xOWgpc.
- Karl’s Round 2: https://youtu.be/mqzyKs2Qvug.
- Karl’s Lecture 1: https://youtu.be/Gp9Sqvx4H7w.
- Karl’s Lecture 2: https://youtu.be/Sfjw41TBnRM
- Karl’s Lecture 3: https://youtu.be/dM3YINvDZsY
- Mark’s Round 1: https://youtu.be/qqM76ZHIR-o.
- Mark’s Round 2: https://youtu.be/rkbeaxjAZm4

CONNECT:

SCP-239: The Child Who Can Rewrite Reality | The Science and Ethics of a Sleeping God

Can a child’s imagination alter the laws of physics? In this speculative science essay, we explore SCP-239, “The Witch Child” — a sleeping eight-year-old whose mind can reshape matter, rewrite probability, and collapse reality itself.

We examine how the SCP Foundation’s containment procedures—from telekill alloys to induced comas—reflect humanity’s struggle to contain a consciousness powerful enough to bend the universe. Through philosophy, ethics, and quantum speculation, this essay asks:
What happens when belief becomes a force of nature?

🎓 About the Series.
This video is part of our Speculative Science series, where we analyze anomalous phenomena through physics, cognitive science, and ethics.

📅 New speculative science videos every weekday at 6 PM PST / 9 PM EST.
🔔 Subscribe and turn on notifications to stay at the edge of what’s possible.

💬 Share your theories in the comments below:
Should SCP-239 remain asleep forever, or does humanity have a moral duty to understand her?

#SCP239 #SpeculativeScience #TheWitchChild #SCPFoundation #ScienceFiction #Philosophy #AIExplained #Ethics #SciFiEssay #LoreExplained

Shall we Dance in Free-Space? a Choice of Freedom!

Humanity stands at a crossroads. Our beautiful Earth, cradle of all we know, is straining under the weight of nearly 8.5 billion people. Environmental degradation, social inequity, and resource scarcity deepen by the day. We are reaching the limits of a single-planet civilization. We can face this challenge in two ways. Some will cling to the old patterns—fighting over dwindling resources and defending narrow borders. Others will rise above, expanding into space not to escape Earth, but to renew and sustain it. These pioneers—the Space Settlers —will carry the next chapter of civilization beyond our home planet.

The Humanist Path: Living in Free Space. When people imagine living beyond Earth, they often picture Lunar or Martian colonies. Yet, from a humanist perspective, a better path exists: rotating free space habitats, as envisioned by Gerard K. O’Neill. These are vast, spinning structures orbiting Earth or the Moon, or standing at Lagrange Libration Points, designed to simulate Earth’s gravity and sustain full, flourishing communities. Unlike planetary colonies bound to weak gravity, dust, or darkness, O’Neill habitats offer: 1g simulated gravity to preserve human health; continuous sunlight and abundant solar energy; freedom of movement, as habitats can orbit safely or relocate if needed. More than technical achievements, these habitats embody the Enlightenment spirit—the belief that reason, ethics, and creativity can design environments of dignity, beauty, and freedom.

Freedom and Human Dignity in Space. Freedom is at the heart of humanity’s destiny. Consider a lunar settler who finds his bones too fragile to withstand Earth’s gravity—trapped by biology, after a few years living on the Moon. In contrast, inhabitants of a rotating habitat retain the freedom to return on Earth, at will. Simulated gravity safeguards their health, ensuring that space settlement remains reversible and voluntary. Freedom of movement leads naturally to freedom of culture. In a habitat like “New Gaia”, thousands of people from all nations live together: Russians celebrating Maslenitsa, Indians lighting Diwali lamps, and space-born storytellers sharing ancient myths. New traditions also emerge—festivals, music, and art inspired by life between worlds. These habitats can become beacons of a new Renaissance —a rebirth of cultural and creative freedom beyond the constraints of geography and politics.

/* */