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Multifold increase in spinal inhibitory cell types with emergence of limb movement

Frog metamorphosis reveals how spinal circuits adapt to new motor demands. Vijatovic et al. demonstrate that the shift from tail-to limb-based locomotion coincides with expansion and diversification of V1 inhibitory neurons. Cross-species comparisons identify a conserved blueprint of tail and limb locomotion, with Engrailed-1 a global regulator of movement frequency.

Scientists say they’ve reversed brain aging with a simple nasal spray

Researchers at Texas A&M have developed a nasal spray that appears to reverse brain aging by calming inflammation and restoring the brain’s energy systems. After just two doses, memory and cognitive function improved for months, raising hopes for future treatments targeting dementia and brain fog.

Conversation with Nic Rouleau, part 1: “Some thoughts on the mind as material”

This is a ~1 hour talk and discussion, comprising part 1 of a conversation with a really interesting young neuroscientist, as well as friend, collaborator, and our Center member, Nicolas Rouleau (https://allencenter.tufts.edu/nicolas… goes over unconventional aspects of neuroscience touching on free will, cybernetics, consciousness, and a lot more. We start a discussion which is continued in part 2. For more information:

Nic’s website: www.rouleaulab.com.
X account: @DrNRouleau.

Recent papers to check out:

Sellar, E.P., Rouleau, N. (In Review). A cybernetic framework for synthetic biological intelligence in the era of neural tissue engineering. Preprint doi: 10.31234/osf.io/md2wf_v1.

Kansala, C., Cicek, E., Nkansah-Okoree, V., Golding, A., Murugan, N.J., Rouleau, N. (In Review). Superstitious conditioning forms the experience of free will under causal determinism. Preprint doi: 10.31234/osf.io/fk3yt_v2.

Roskies, A. \& Rouleau, N. (Forthcoming, In Press). Research on brain organoids should prioritize questions of agency, not consciousness. AJOB Neuroscience.

Scientists create supercharged vitamin K that helps the brain heal itself

Scientists in Japan have created powerful new vitamin K-based compounds that may help the brain regenerate lost neurons — a breakthrough that could one day change how diseases like Alzheimer’s and Parkinson’s are treated. By combining vitamin K with components related to vitamin A, the researchers developed compounds that were about three times more effective at turning neural stem cells into neurons than natural vitamin K alone.

Scientists Create the First Artificial Neuron That Can Communicate

A major breakthrough in artificial intelligence may have arrived: scientists have created an artificial neuron capable of communicating with other neurons.

Inspired by the human brain, this technology could allow machines to process information in a far more biological and efficient way. Instead of traditional computing architectures, future systems could operate more like living neural networks.

In this video we explore how artificial neurons work, why this breakthrough matters, and how it could reshape AI, robotics, and neuroscience.

#ArtificialNeuron, #ArtificialIntelligence, #Neuroscience, #FutureTechnology, #AIResearch, #NeuralNetworks

AI-Powered BCIs Are Changing Human Cognition

Further Reading.

N3: Next-Generation Nonsurgical Neurotechnology.
https://www.darpa.mil/research/progra

Advancements in neural closed-loop manipulations in awake, behaving animals.
https://www.sciencedirect.com/science

INSIGHT: Universal Neural Simulator for Analog Circuits Harnessing Autoregressive Transformers.
https://arxiv.org/abs/2407.

MouseGoggles: an immersive virtual reality headset for mouse neuroscience and behavior.
https://www.nature.com/articles/s4159

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