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Researchers have developed a brain-computer interface the size of a baby aspirin that can restore mobility to people with paralysis or amputated limbs.

How does it work? It rewires neural messages from the brain’s motor cortex to a robotic arm, or reroutes it to the person’s own muscles. In this video, Big Think contributor Susan Hockfield, president emerita of MIT, explains further.

In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age. The study provides evidence that this occurs even in people with cognitive impairment and Alzheimer’s disease, although neurogenesis is significantly reduced in these people compared to older adults with normal cognitive functioning.

They publish their results in the journal Cell Stem Cell.

The idea that new neurons continue to form into middle age, let alone past adolescence, is controversial, as previous studies have shown conflicting results. The UIC study is the first to find evidence of significant numbers of neural stem cells and newly developing neurons present in the hippocampal tissue of older adults, including those with disorders that affect the hippocampus, which is involved in the formation of memories and in learning.

Continue reading “New neurons form in the brain into the tenth decade of life, even in people with Alzheimer’s” »

A neuroscientist on how we came to be aware of ourselves.

The electronic Barnett effect, first observed by Samuel Barnett in 1915, is the magnetization of an uncharged body as it is spun on its long axis. This is caused by a coupling between the angular momentum of the electronic spins and the rotation of the rod.

Using a different method from that employed by Barnett, two researchers at NYU observed an alternative version of this effect called the nuclear Barnett effect, which results from the magnetization of protons rather than electrons. Their study, published in Physical Review Letters (PRL), led to the first experimental observation of this effect.

“I was a graduate student at NYU where a group of colleagues were involved in a project related to brain imaging,” Mohsen Arabgol, one of the researchers who carried out the study, told Phys.org. The fundamental idea behind the project was polarizing the brain molecules by inducing rotation using the Barnett effect and then applying the MRI-type imaging. I became interested and decided to work on the detection of the nuclear Barnett effect as my Ph.D. dissertation.”

Continue reading “The first observation of the nuclear Barnett effect” »

A growing body of research suggests that exposure to air pollution in the earliest stages of life is associated with negative effects on cognitive abilities. A new study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by “la Caixa”, has provided new data: exposure to particulate matter with a diameter of less than 2.5 μm (PM2.5) during pregnancy and the first years of life is associated with a reduction in fundamental cognitive abilities, such as working memory and executive attention.

The study, carried out as part of the BREATHE project, has been published in Environmental Health Perspectives. The objective was to build on the knowledge generated by earlier studies carried out by the same team, which found lower levels of cognitive development in children attending schools with higher levels of traffic-related air pollution.

The study included 2,221 children between 7 and 10 years of age attending schools in the city of Barcelona. The children’s cognitive abilities were assessed using various computerized tests. Exposure to air pollution at home during pregnancy and throughout childhood was estimated with a mathematical model using real measurements.

Continue reading “Exposure to air pollution before and after birth may affect fundamental cognitive abilities” »

A molecule produced by the body during fasting or calorie restriction has anti-aging effects on the vascular system, which could reduce the occurrence and severity of human diseases related to blood vessels, such as cardiovascular disease, according to a study led by Georgia State University.

“As people become older, they are more susceptible to disease, like cancer, cardiovascular disease and Alzheimer’s disease,” said Dr. Ming-Hui Zou, senior author of the study. “Age is the most important so-called risk factor for human disease. How to actually delay aging is a major pathway to reducing the incidence and severity of human disease.

People who suffer a stroke caused by bleeding in the brain—known as brain haemorrhage—can take common medicines without raising their risk of another stroke, a major clinical trial has found.

Researchers say the findings are reassuring for the thousands of people who take the medicines to reduce their risk of heart attack and another common type of stroke caused by blood clots in the brain.

These everyday treatments—known as antiplatelet medicines—work by slowing or stopping blood from clotting. They are often prescribed to older people because they can lower risk of heart attack and stroke caused by a blood clot.

Continue reading “Aspirin green light for brain bleed stroke patients, study finds” »

Injection of human neural stem cells into the spinal cord of people with amyotrophic lateral sclerosis (ALS) was found safe and did not cause adverse effects even two years after the transplant, results from a Phase 1 clinical trial show.

Trial findings were published in the study, “Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome,” in the journal Stem Cells Translational Medicine.

People who have bipolar disorder may be more likely to later develop Parkinson’s disease than people who do not have bipolar disorder, according at a study published in the May 22, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.

“Previous studies have shown a relationship between depression and Parkinson’s disease, but few studies have looked at whether there is a relationship between bipolar disorder and Parkinson’s,” said study author Mu-Hong Chen, MD, Ph.D., of Taipei Veterans General Hospital in Taiwan.

For the study, researchers examined a national Taiwanese health database for people were diagnosed with bipolar disorder between 2001 and 2009 and who had no history of Parkinson’s disease, for a total of 56,340 people. They were matched with 225,360 people of the same age, sex and other factors who had never been diagnosed with bipolar disorder or Parkinson’s disease as a control group. Then the two groups were followed until the end of 2011.

Continue reading “Bipolar disorder may be linked to Parkinson’s disease” »