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Archive for the ‘aging’ tag

Sep 9, 2018

The Alzheimer’s Hypothesis

Posted by in categories: aging, genetics, health, neuroscience, science

The Alzheimer’s Hypothesis

Introduction

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Sep 4, 2018

Bioquark Inc. — 2bAhead Conference Video — Ira S. Pastor

Posted by in categories: aging, bioengineering, biological, biotech/medical, DNA, evolution, futurism, health, life extension, transhumanism

https://speaker.future.consulting/en/home/search/video/video…re-cancer/

Jun 17, 2018

Harvard Rewinds the Biological Clock of Time

Posted by in categories: bioengineering, biological, DNA, health, life extension, science, transhumanism

Investigators at Harvard Medical School have identified the key cellular mechanisms behind vascular aging and its effects on muscle health, and they have successfully reversed the process in animals.

The scientists used a chemical compound that’s an NAD+ booster called NMN which plays a critical role in repairing cellular DNA as well as maintaining cell vitality to test what would happen.

Could reversing the aging of blood vessels hold the key to restoring youthful vitality? If the old adage “you are as old as your arteries” reigns true then the answer is yes, at least in mice.

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Jun 9, 2018

Human Skeletal Muscle Aging and Mutagenesis

Posted by in categories: aging, DNA, genetics, health, life extension

Study based upon human skeletal muscle aging, mutagenesis, and the role of #satellite cells.

“A more comprehensive understanding of the interplay of stem cell–intrinsic and extrinsic factors will set the stage for improving cell therapies capable of restoring tissue homeostasis and enhancing muscle repair in the aged.”

Human aging has multiple effects on the human body. One of the effects of human aging is the reduction in skeletal muscle (SkM) function and a reduction in the number and activity of satellite cells (SCs), the resident stem cells. The whole genome of single SC clones of the leg muscle vastus lateralis from healthy individuals of different ages (21–78 years) was analyzed, to study the specific connection between SC aging and muscle impairment. In healthy adult muscle rapid increase of SCs is consistent with the accumulation rate of 13 somatic mutations per genome per year. Mutations typically do not happen in SkM-expressed genes because they are protected. However, as mutations in exons and promoters increase, genes involved in SC activity and muscle function are targeted which results in aging. Exons are coding sections of an RNA transcript, or the DNA encoding it, that are translated into protein. Proteins are the synthesis of molecules. A change in of a single base pair that caused the substitution of a different amino acid in the resulting protein (missense mutation) that was propagated to the muscle and detected in association with SC mutations affecting the whole tissue. #Somatic mutagenesis in SCs as a result is the driving force in the age related decline of SkM function.

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Mar 21, 2018

Bioquark Inc. — Al Bayan News (UAE) — AI and Health — Ira Pastor

Posted by in categories: aging, automation, big data, bioengineering, biotech/medical, business, computing, genetics, health

https://www.albayan.ae/middle-east-dialogue/2018-03-20-1.3214947

Mar 20, 2018

Bioquark Inc. — Senior Care — Reversal Of Age-Related Diseases — Ira Pastor

Posted by in categories: aging, bioengineering, biological, biotech/medical, disruptive technology, DNA, futurism, genetics, health, science

Mar 19, 2018

Bioquark Inc. — Health:Further — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, business, DNA, finance, health, life extension, science, transhumanism

Mar 6, 2018

Bioquark Inc. — Creative Futurism — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, cosmology, cryonics, DNA, futurism, health, military, science

http://www.creativefuturism.com/bioengineering-superhumans-fact-not-fiction/

Jan 23, 2018

Bioquark Inc. — Bloomer Boomer — “Plus 50″ Good Life Movement — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, cryonics, disruptive technology, futurism, genetics, health, science, transhumanism

Human Rejuvenation and Longevity – Inspired By Nature

Jan 23, 2018

Bioquark Inc. — Staying Alive UK Show — Ira S. Pastor

Posted by in categories: aging, bioengineering, biotech/medical, business, disruptive technology, DNA, futurism, genetics, health, neuroscience

https://www.stayingaliveuk.com/podcast/2018/1/0036-ira-s-pas…trepreneur

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