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Category: mobile phones

Activated neutrophils are a hallmark of acute lung injury

Here, Dolly Mehta & team find loss of ERG in endothelial cells alters neutrophil transcriptome towards inflammatory lineage via IL8/CXCR2 and CXCR2 blockade with Reparixin reduces inflammation, neutrophil infiltration, and improves survival in a pneumonia model.

The figure shows mouse lungs 30 minutes after antibody administration, with increased number of neutrophils (green) in Erg-null mice compared with Ergfl/fl mice. Endothelium (red).

1Department of Pharmacology and Regenerative Medicine, and.

2Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois Chicago, College of Medicine, Chicago, Illinois, USA.

Address correspondence to: Dolly Mehta, Department of Pharmacology and Regenerative Medicine, University of Illinois, Chicago, College of Medicine, 835 S. Wolcott Avenue, Chicago, Illinois 60,612, USA. Phone: 312.355.0236; Email: dmehta@uic.edu.

Good Morning! ☀️

Things are going well with this startup that we are building in stealth mode, and I couldn’t be happier about our progress.

But, we are still pre-investment / pre-revenue and I need to find some income to keep the bills paid while we are continuing to build.

I have the free time, and I have all the equipment necessary to do almost anything related to sales, marketing, production, and promotion of products and services.

I’m adept with AI and can help you with real solutions for your business or personal life.

I’m not looking for full-time, or long term work. Campaigns, projects, implementation and development of products and services.

I also have experience in events, trade shows, and conferences if anyone needs additional hands on their next summit or symposium.

I appreciate anything that comes along, at 66 the corporations won’t hire me anymore and so I forced to reach out to my friends and neighbors for opportunities and income.

Continue reading “Good Morning! ☀️” | >

Abstract: In obesity, the heart muscle can thicken, preventing it from relaxing properly between beats

While diet and inflammation likely contribute, the underlying molecular mechanism has been unclear.

https://doi.org/10.1172/JCI196238 Here, Junichi Sadoshima & team find direct stimulation of IL-6 transcription by PPARα in cardiomyocytes plays an important role in mediating the initial development of obesity cardiomyopathy.

The figure indicates binding of PPARα to NFkB (via PLA assay).

1Rutgers New Jersey Medical School Department of Cell Biology and Molecular Medicine, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA.

2Precision Medicine Research Center, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Address correspondence to: Junichi Sadoshima, Cardiovascular Research Institute, Rutgers Biomedical and Health Science, 185 South Orange Ave., MSB G609, Newark, New Jersey, 7,103, USA. Phone 973.972.8619; Email: sadoshju@njms.rutgers.edu.

Continue reading “Abstract: In obesity, the heart muscle can thicken, preventing it from relaxing properly between beats” | >

The sun is tearing an asteroid to pieces, and Earth is now flying through the fallout

Across Earth, every night, thousands of automated stargazers are waiting to take pictures of shooting stars. I am one of the scientists who study these meteors.

Most movies and news alerts focus on large asteroids that could destroy Earth. And your phone notifies you every few months that an object nine washing machines wide is going to just narrowly skim past. However, the small dust and rubble that enter our atmosphere daily tell an equally interesting story.

My planetary science colleagues and I use camera observations of the night sky to better understand dust, car-sized asteroids and debris from comets in our solar system.

Google rolls out Gmail end-to-end encryption on mobile devices

Google says Gmail end-to-end encryption (E2EE) is now available on all Android and iOS devices, allowing enterprise users to read and compose emails without additional tools.

Starting this week, encrypted messages will be delivered as regular emails to Gmail recipients’ inboxes if they use the Gmail app.

Recipients who don’t have the Gmail mobile app and use other email services can read them in a web browser, regardless of the device and service they’re using.

Abstract: Do cells of different lineages age differently?

https://doi.org/10.1172/JCI195772 Sundeep Khosla & team compare the senescence phenotype of mesenchymal versus immune cells from murine bone and bone marrow, revealing important differences between them.

The figure shows mesenchymal cells exhibit higher absolute levels of senescence signatures than immune cells.

Address correspondence to: Madison L. Doolittle, Center for Regenerative Medicine and Skeletal Development, UConn Health, 263 Farmington Avenue, Farmington, Connecticut 6,030, USA. Phone: 860.679.1757; Email: mdoolittle@uchc.edu. Or to: Sundeep Khosla, Guggenheim 7, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minnesota 55,905, USA. Phone: 507.255.6663; Email: khosla.sundeep@mayo.edu.

Research moves closer to ‘smart’ sensors in knee replacements

If you have a knee replacement, imagine pointing your phone at your knee and pulling up an app that tells you how much stress the artificial joint is experiencing. Knowing the activities that cause the biggest problems—which can lead to a second replacement surgery—would be invaluable. Research led by Binghamton University is closer to making this technology a reality.

Professor Shahrzad “Sherry” Towfighian—a faculty member from the Thomas J. Watson College of Engineering and Applied Science’s Department of Mechanical Engineering—has worked toward “smart-knee” tech over the past decade.

According to the American College of Rheumatology, nearly 800,000 total knee replacements are done every year in the U.S., and that number is expected to rise sharply by 2030 as the population ages and sports injuries become more common.

‘NoVoice’ Android malware on Google Play infected 2.3 million devices

A new Android malware named NoVoice was found on Google Play, hidden in more than 50 apps that were downloaded at least 2.3 million times.

The apps carrying the malicious payload included cleaners, image galleries, and games. They required no suspicious permissions and provided the promised functionality.

After launching an infected app, the malware tried to obtain root access on the device by exploiting old Android vulnerabilities that received patches between 2016 and 2021.

Scientists capture atoms in motion, unlocking next-generation memory technology

Monash University researchers have captured the exact atomic movements that write data to next-generation memory devices, which could pave the way for smaller, faster and more energy-efficient electronics. Published in Nature Communications, the study was led by Dr. Kousuke Ooe, a Japan Society for the Promotion of Science (JSPS) postdoctoral fellow in the School of Physics and Astronomy at Monash University who is first author of the paper, in collaboration with Australian Laureate Professor Joanne Etheridge and researchers from the Japan Fine Ceramics Center, Kyoto University, and the University of Osaka.

Using advanced electron microscopy at the Monash Center for Electron Microscopy (MCEM), the team captured atomic-scale movements inside promising memory materials, known as fluorite-type ferroelectrics, that could overcome current limits to how small and efficient memory devices can become.

Everyday technologies, such as smartphones, medical devices, wearable electronics and contactless IC cards used in public transport, store data as billions of digital 1s and 0s. In these materials, the physical position of an atom acts like a “switch”—and moving an atom just a fraction of a nanometer is what flips a data bit from a 0 to a 1.

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