Lifeboat Foundation

Antípodas.

Antipodes map helps you find the other side of the world, the antipodes of any place on Earth. This map shows diametrically opposite location named antipode or antipodal point.

Earlier this month, there was a human clinical trial of the supplement MitoQ, which showed some interesting results. We thought that we would take a look at the data, and discuss the findings.

Excess reactive oxygen species production by mitochondria is a key mechanism of age-related vascular dysfunction. Our laboratory has shown that supplementation with the mitochondrial-targeted antioxidant MitoQ improves vascular endothelial function by reducing mitochondrial reactive oxygen species and ameliorates arterial stiffening in old mice, but the effects in humans are unknown. Here, we sought to translate our preclinical findings to humans and determine the safety and efficacy of MitoQ. Twenty healthy older adults (60–79 years) with impaired endothelial function (brachial artery flow–mediated dilation 6%) underwent 6 weeks of oral supplementation with MitoQ (20 mg/d) or placebo in a randomized, placebo-controlled, double-blind, crossover design study.

A new wonderful breakthrough of our time.

Scientists raise ethical concerns as the brain cells of decapitated pigs are kept alive for 36 hours.

Sounds neat.

Memories are transferred from one snail to another in a laboratory.

New video from Undoing Aging 2018: Mike West, Founder, and CEO of AgeX, presenting their work on induced tissue regeneration: Leveraging the unique regenerative potential of pluripotent stem-cell-derived therapeutics.

Accelerating rejuvenation therapies to repair the damage of aging. Berlin, March, 15 — 17.

Continue reading “Mike West, CEO AgeX, at” »

New video from Undoing Aging 2018: John Lewis, CTO of Oisín Biotechnologies presenting their work developing very selective therapies to kill senescence cells.

Accelerating rejuvenation therapies to repair the damage of aging. Berlin, March, 15 — 17.

Continue reading “John Lewis, CSO of Oisin Biotechnologies, presenting at” »

In 2022, NASA’s Double Asteroid Redirection Test (DART) collides with the smaller body of the Didymos binary asteroid system in an attempt to measurably shift its orbit.

ESA’s Hera mission, now under study, will examine the aftermath of this impact to help determine whether humans can deflect threatening asteroids.

Hera will also demonstrate the ability to operate at close proximity around a low-gravity asteroid with some on-board autonomy similar in scope to a self-driving car, going on to deploy Europe’s first deep-space CubeSats, and potentially also a micro-lander, to test out a new multi-point intersatellite link technology.

In the United States, the energy market dynamics are quite different. There is less top-down pressure to deploy renewables in the US, and the main support comes in the form of tax credits on the back end rather than feed-in tariffs or other subsidies on the customer-facing side. These subsidies are applied across the industry and not through a competitive bidding process. As a result, there isn’t as strong a push to get the industry off the incentives that are available.

But one element of the American renewable energy experience is gaining ground in Europe, namely the use of power purchasing agreements (PPAs) with utilities to buy electricity at a fixed price for years at a time.

PPAs are far less common in Europe than in the United States, but some of these new unsubsidized renewable energy projects are counting on them.

Continue reading “Europe is building more wind and solar — without any subsidies” »

Research on people’s reaction to life extension is rather rare; this article discusses two such papers.

Two papers by Partridge et al [1, 2], both published in 2009, provide the somewhat rare opportunity to examine some concerns about life extension as formulated by actual people, rather than their general, more abstract forms. As highlighted in the studies, research on the public’s perception of life extension science has been very much neglected; this, in turn, has made it harder to identify the misconceptions and incorrect information fueling some common concerns about life extension and made it even harder to address those very concerns. Needless to say, the more that the public views life extension negatively, the less supportive that it will probably be, which is bad news for researchers.

The papers present the results of several interviews, conducted either in person or on the phone, aimed at understanding what ethical concerns the interviewees had about life extension and what implications they thought extended human lifespans would have for themselves and for society. The research was conducted on a sample of the Australian population only, but the issues they raised were entirely representative of a typical discussion about life extension. In both studies, the interviewees were presented with the general premise of possibly slowing down aging and the onset of age-related diseases in order to greatly extend human healthy lifespan.

Continue reading “Popular reactions to life extension” »