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Dyson Strawberry Farming: 5,127 Prototypes to 250% Yields

When James Dyson built his 5,127th prototype of a bagless vacuum cleaner, he had no idea that the same relentless engineering philosophy would one day transform him into Britain’s largest farmer. Today, Dyson strawberry farming represents one of the most ambitious applications of high-tech innovation to agriculture ever attempted in the United Kingdom.

The numbers tell an extraordinary story. After spending five years and creating over five thousand prototypes to perfect a single vacuum cleaner design, Dyson has now invested £140 million into a farming operation spanning 36,000 acres across five English counties. At the heart of this agricultural empire sits a 26-acre glasshouse in Lincolnshire, home to 1.25 million strawberry plants and technology that has increased yields by 250% compared to traditional farming methods.

This isn’t farming as your grandparents would recognize it. Inside Dyson’s facility, massive 5.5-meter “ferris wheel” structures rotate strawberry plants through optimal sunlight positions. Sixteen robotic arms delicately harvest ripe fruit using computer vision. UV-emitting robots patrol the aisles at night, destroying mould without chemicals. And all of it runs on renewable energy generated from an adjacent anaerobic digester.

Lung Sparing Surgery Is Possible for Patients With COPD

Patients with COPD may be especially hesitant about lung surgery when facing lung cancer, but surgery remains the most effective treatment for non–small cell lung cancer when feasible, according to experts. For those who are not surgical candidates, less invasive options exist, with stereotactic body radiation therapy (SBRT) the standard noninvasive treatment for early-stage disease, delivering targeted high-dose radiation over three to five sessions while sparing healthy tissue.

Some individuals with COPD and lung cancer may be eligible for less invasive options.

The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth

Immune and stromal orchestration of the pre-metastatic niche👇

✅Priming distant organs before tumor cell arrival Primary tumors actively condition distant organs by releasing soluble factors, cytokines, and tumor-derived exosomes. These signals recruit monocytes and neutrophils and reprogram resident immune and stromal cells, initiating the formation of a pre-metastatic niche (PMN) that becomes permissive to future metastatic seeding.

✅Role of monocytes and macrophages Recruited monocytes differentiate into inflammatory or immunosuppressive macrophages depending on the local context. In organs such as the lung and liver, these cells promote extracellular matrix (ECM) remodeling, fibrotic deposition, and secretion of growth factors, creating a supportive scaffold for disseminated tumor cells (DTCs).

✅Neutrophils as niche architects Neutrophils contribute to PMN formation through the release of matrix metalloproteinases (MMPs), inflammatory cytokines, and neutrophil extracellular traps (NETs). These processes alter tissue architecture, enhance inflammation, and support tumor cell survival and reactivation.

✅Organ-specific niche specialization Different organs develop distinct PMNs. In the lung, inflammatory macrophages and neutrophils drive ECM remodeling and leukotriene signaling. In the liver, fibrosis, granulins, and chemokine-driven immune cell recruitment promote an immunosuppressive environment favorable for metastatic colonization.

✅Fate of disseminated tumor cells Once DTCs arrive, they face multiple outcomes. Some are eliminated by immune surveillance, others enter long-term dormancy, and a subset evades immunity to initiate metastatic outgrowth. ECM composition, immune pressure, and stromal signaling critically determine these divergent fates.

✅Dormancy and reawakening Dormant DTCs can persist in a latent state for prolonged periods. Changes in ECM remodeling, inflammatory signaling, or immune suppression can trigger their reawakening, leading to renewed proliferation and metastatic progression.

Continue reading “The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth” | >

Out-of-season water escape during Mars’ northern summer triggered by a strong localized dust storm

Observations compiled from several Mars observation missions suggest a significant but short-lived dust storm during the Northern hemisphere summer of Mars Year 37 drove substantial vertical transport of water vapor into the upper atmosphere.

Aerobic respiration began hundreds of millions of years earlier than previously thought, study suggests

Oxygen is a vital and constant presence on Earth today. But that hasn’t always been the case. It wasn’t until around 2.3 billion years ago that oxygen became a permanent fixture in the atmosphere, during a pivotal period known as the Great Oxidation Event (GOE), which set the evolutionary course for oxygen-breathing life as we know it today. A new study by MIT researchers suggests some early forms of life may have evolved the ability to use oxygen hundreds of millions of years before the GOE. The findings may represent some of the earliest evidence of aerobic respiration on Earth.

In their study published in the journal Palaeogeography, Palaeoclimatology, Palaeoecology, MIT geobiologists traced the evolutionary origins of a key enzyme that enables organisms to use oxygen. The enzyme is found in the vast majority of aerobic, oxygen-breathing lifeforms today. The team discovered that this enzyme evolved during the Mesoarchean —a geological period that predates the Great Oxidation Event by hundreds of millions of years.

The team’s results may help to explain a longstanding puzzle in Earth’s history: Why did it take so long for oxygen to build up in the atmosphere?

Big Bang May Not Be The Beginning of Everything, New Theory Suggests

The Big Bang is often described as the explosive birth of the Universe – a singular moment when space, time and matter sprang into existence.

But what if this was not the beginning at all? What if our Universe emerged from something else – something more familiar and radical at the same time?

In a new paper, published in Physical Review D, my colleagues and I propose a striking alternative. Our calculations suggest the Big Bang was not the start of everything, but rather the outcome of a gravitational crunch or collapse that formed a very massive black hole – followed by a bounce inside it.

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