Nishada Ramphal, Ari Waisman et al. (Johannes Gutenberg-Universität Mainz) reveal that NIK drives neuroantigen-specific T cell priming by regulating antigen presentation and IL-23 production, identifying NIK as a key orchestrator of myeloid-driven CNS autoimmunity.
Neuroinflammation.
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Zhen et al. show that micro-/nanoplastics increase antimicrobial resistance gene abundance and mobilization in mixed microbial consortia. Nanoplastics intensify oxidative stress and SOS responses and strengthen ARG-MGE co-localization, promoting dense horizontal gene transfer networks and turning plastisphere biofilms into resistance hotspots.
Amin et al. present telomere-to-telomere assemblies of nine Borrelia burgdorferi strains from Canada, uncovering the diversity at chromosome ends and plasmid profiles. They identify an lp28-1a plasmid subtype and detect plasmid-chromosome recombination, offering insights into genomic plasticity and potential mechanisms of adaptation in Borrelia.
Purified diets offer compositionally defined platforms that improve causal inference in nutrition studies. When aligned with the biological question, they enable targeted nutrient loss- and gain-of-function experiments, systematic lipid-source swaps, and the discovery of diet-microbiome-drug interactions. We recommend complementary validation in grain-based chow or human-relevant diets to maximize translational relevance.
Superconducting computing circuits were briefly heralded as the future of computing in the 1980s. Columnist Karmela Padavic-Callaghan visits a quantum chip foundry where one company is betting this technology’s second act will revolutionise quantum computers.
Here I solved two problem and describe generalize charge potential in electro magnet.
“If you don’t know exactly how much emissions you have, then it’s really difficult to make effective policies or technologies or methods to reduce the emissions,” said Dr. Z. Jason Ren. [ https://www.labroots.com/trending/earth-and-the-environment/…-reports-2](https://www.labroots.com/trending/earth-and-the-environment/…-reports-2)
Are national climate reports missing crucial data points regarding wastewater greenhouse gas (GHG) emissions? This is what a recent study published in Nature Climate Change hopes to address as a team of researchers investigated the accuracy of national inventory reports (NIRs) for wastewater GHG. This study has the potential to help researchers, climate scientists, legislators, and the public better understand the methods for tracking climate change and steps that can be taken to fill the gaps in report lapses.
For the study, the researchers obtained data from 38 countries regarding wastewater GHG emissions with the goal of ascertaining existing data gaps in NIRs. The motivation of this study comes from the lack of consistent data methods and large changes that occur over many years and in global regions. The overarching goal of the study was to ascertain where the data gaps exist and how to fill them.
In the end, the researchers discovered massive data gaps in wastewater GHG emissions, including an unreported gap of 52.0–73.2 million metric tons (MMT) of CO2-equivalent (CO2e) annually across the 38 countries. Additionally, they found that global gap of 94–150 MMT CO2e annually.