NGate abuses HandyPay in Brazil since Nov 2025, stealing NFC data and PINs to enable ATM fraud and unauthorized payments.
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Former ransomware negotiator pleads guilty to BlackCat attacks
41-year-old Angelo Martino, a former employee of cybersecurity incident response company DigitalMint, has pleaded guilty to targeting U.S. companies in BlackCat (ALPHV) ransomware attacks in 2023.
Together with two other Sygnia and DigitalMint ransomware negotiators (33-year-old Ryan Clifford Goldberg and 28-year-old Kevin Tyler Martin), Martino was charged with conspiracy to interfere with interstate commerce by extortion, interference with interstate commerce by extortion, and intentional damage to protected computers.
Martino was initially identified only as “Co-Conspirator 1” in an October 2025 indictment, but was named in court documents unsealed in March. Martin and Goldberg also pleaded guilty to conspiracy to obstruct commerce by extortion and are facing up to 20 years in prison each.
UK probes Telegram, teen chat sites over CSAM sharing concerns
Ofcom, the United Kingdom’s independent communications regulator, has launched an investigation into Telegram based on evidence suggesting it’s being used to share child sexual abuse material (CSAM).
The investigation was launched under the UK’s Online Safety Act to examine whether the social media and instant messaging (IM) service is complying with its illegal content safety duties, which require it to prevent CSAM from being shared.
Ofcom says it received evidence regarding the alleged presence and sharing of CSAM on Telegram from the Canadian Centre for Child Protection, and that it had also conducted its own assessment of the platform.
New study reveals CRISPR enzyme that responds to human DNA methylation
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of scientists from Wageningen University & Research and Van Andel Institute has identified a way to exploit this distinction. Using a variant of CRISPR, a modern tool for editing DNA, they distinguished tumor DNA from healthy DNA and selectively cut only the former. The study, published today in Nature, is an early but promising step toward a cancer therapy that targets and destroys tumor cells with high precision.
The new method relies on methyl groups, small chemical tags attached to DNA that regulate whether genes are on or off. This process, called DNA methylation, is altered in cancer cells and can act as a molecular “fingerprint” that differentiates malignant cells from healthy ones.
Survival strategies of Rhinocladiella similis in perchlorate-rich Mars like environments
Fungi can live on mars face_with_colon_three
Dos Santos, A., Schultz, J., Souza, F.O. et al. Survival strategies of Rhinocladiella similis in perchlorate-rich Mars like environments. npj Microgravity 11, 18 (2025). https://doi.org/10.1038/s41526-025-00475-y.
Secondary causes of diabetes: a crossroad of endocrinology and oncology
Cancer and diabetes share a bidirectional relationship, with cancer increasingly recognised as an associated factor of diabetes, both from the disease itself and its treatments. In this Review, we aim to: summarise the distinct mechanisms of dysglycaemia arising from cancer and neuroendocrine tumour treatments, including targeted therapies such as PI3K–AKT–mTOR inhibitors, antibody–drug conjugates, immune checkpoint inhibitors, corticosteroids, and somatostatin receptor ligands; examine the often overlooked aspect of the secondary cause of diabetes as an early manifestation of cancer; and highlight research gaps and encourage a collaborative care approach to manage the rising rate of dysglycaemia as a result of cancer and its evolving treatments.
The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
Proinflammatory lytic cell death releases cytosolic TRIM21, which binds to circulating antibodies and is internalized by macrophages, stimulating cross-antigen presentation and inflammation in Sjögren’s disease.
Learn more in Science Immunology.
TRIM21/Ro52 assembles proinflammatory immune complexes.
De novo fast motion computation in the primate visual cortex
He et al. suggest that MT and MST neurons can generate velocity selectivity anew by integrating sequential visuotopic activations from the V1 rather than by simple inheritance, as the V1 is no longer direction selective at high speeds. This de novo velocity computation provides a parsimonious explanation for fast motion processing in the primate brain.
