Even the most skilled face recognizers are duped by AI-generated faces, a new study finds. But they can improve with training.
NOTE: Some folks have mentioned my pronunciation of Gödel is wrong, I do apologize for that.
Any author mulling artificial intelligence as a story element owes it to themselves to encounter this spellbinding, one-of-a-kind book. You also deserve to sit down with it if you’re curious about any number of other SF&F-adjacent topics: mathematics, pattern recognition, the definition of consciousness, the concepts of recursion (finite and infinite)… but most of all, the way profundity can be made to look like pure play.
“Gödel, Escher, Bach” at Amazon.com: https://www.amazon.com/dp/0465026567?tag=lifeboatfound-20
Opening music: “Crystal City” by Karl Casey @ White Bat Audio.
Opening background: “XANNN” @ https://vimeo.com/165286507 (Creative Commons)
My SF&F writing: https://www.infinimata.com/writing/
My blog: https://www.infinimata.com/b/
Buy me something interesting: https://www.amazon.com/hz/wishlist/ls/ZCWCKOKV6N9O?tag=lifeboatfound-20
Buy me coffee, keep me going: https://ko-fi.com/infinimata
Douglas Hofstadter talks about how he came to write his Pulitzer Prize–winning book Gödel, Escher, Bach.
WATCH THE FULL INTERVIEW
• Gödel, Escher, Bach author Doug Hofstadter…
READ \
Deep transfer learning using presurgical brain MRI features predicted post–cochlear implant language improvement in children with 92% accuracy, outperforming traditional ML.
Importance Cochlear implants substantially improve spoken language in children with severe to profound sensorineural hearing loss, yet outcomes remain more variable than in children with healthy hearing. This variability cannot be reliably predicted for individual children using age at implant or residual hearing. Development of an artificial intelligence clinical tool to predict which patients will exhibit poorer improvements in language skills may enable an individualized approach to improve language outcomes.
Objective To compare the accuracy of traditional machine learning (ML) with deep transfer learning (DTL) algorithms to predict post–cochlear implant spoken language development in children with bilateral sensorineural hearing loss using a binary classification model of high vs low language improvers.
Design, Setting, and Participants This multicenter diagnostic study enrolled children from English-, Spanish-, and Cantonese-speaking families across 3 independent clinical centers in the US, Australia, and Hong Kong. A total of 278 children with cochlear implants were enrolled from July 2009 to March 2022 with 1 to 3 years of post–cochlear implant outcomes data. All children underwent pre–cochlear implant 3-dimensional volumetric brain magnetic resonance imaging (MRI). ML and DTL algorithms were trained to predict high vs low language improvers in children with cochlear implants using neuroanatomical features from presurgical brain MRI. Data were analyzed from August 2023 to April 2025.
In this video, we break down six major scientific breakthroughs from July to September that are pushing us closer to true age reversal — from AI-designed drugs and senolytics to epigenetic reset and real human results.
You’ll see how AI, wet-lab automation, and new biomarkers are accelerating longevity research faster than ever before — and what this means for your future healthspan.
0:51 — Breakthrough #1: AI Becomes the Scientist.
1:30 — Breakthrough #2: Reprogramming at 50× Speed.
2:24 — Breakthrough #3: Human Results Are Finally Here.
2:52 — Breakthrough #4: AI Discovers Drugs From Scratch.
3:38 — Breakthrough #5: Aging Now Has a Dashboard.
4:12 — Breakthrough #6: The Telomere Puzzle (TEN1)
4:38 — The Double-Edged Sword of Rejuvenation.
5:04 — The LEV Cycle.
📌 ABOUT THIS CHANNEL
Easy Insight simplifies the science of longevity — from AI-driven age reversal and gene editing to breakthroughs that could let us outpace aging itself.
No hype. No speculation. Just easy, factual insight into how technology may redefine human healthspan.
🔍 KEY TOPICS
longevity, AI longevity, artificial intelligence, anti-aging, rejuvenation, CRISPR, epigenetic reprogramming, healthspan extension, age reversal, LongevityEscapeVelocity, biotechnology, Easy Insight, biomarkers, senolytics, telomeres.
💬 JOIN THE CONVERSATION
What would you do with 100 healthy years?
Share your thoughts in the comments 👇
👍 Like if this video made you think deeper.
🔔 Subscribe to follow the science of living longer, better:
https://youtube.com/@EasyInsight-4everyone.
🎧 AUDIO + VISUAL PRODUCTION
The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a Science study from earlier this year in mice.
The results suggest a potential new target for treating obesity-related metabolic disease.
Insulin resistance is a hallmark of obesity-associated type 2 diabetes. Insulin’s actions go beyond metabolic cells and also involve blood vessels, where insulin increases capillary blood flow and delivery of insulin and nutrients. We show that adrenomedullin, whose plasma levels are increased in obese humans and mice, inhibited insulin signaling in human endothelial cells through protein-tyrosine phosphatase 1B–mediated dephosphorylation of the insulin receptor. In obese mice lacking the endothelial adrenomedullin receptor, insulin-induced endothelial nitric oxide–synthase activation and skeletal muscle perfusion were increased. Treating mice with adrenomedullin mimicked the effect of obesity and induced endothelial and systemic insulin resistance. Endothelial loss or blockade of the adrenomedullin receptor improved obesity-induced insulin resistance.
Li et al. report that ID1 sustains STING activation and innate immunity by blocking PRMT5-STING binding, thereby preventing PRMT5-mediated methylation at Arg281 of STING. The PRMT5 inhibitor EPZ015666 enhances STING activation by suppressing PRMT5, providing a therapeutic candidate for antiviral treatment.