Adults with prediabetes randomized to 8-weeks of walking realized gut microbiome changes suggestive of more resilience, growth, and enhanced metabolic activity. DOCM
Read here ➡️ doi.org/10.2337/doc25-0067
American Diabetes Association American Diabetes Association – DiabetesPro
OBJECTIVE. To test the effect of physical activity on the gut microbiome and circulating short-chain fatty acids (SCFAs) among sedentary adults with prediabetes and overweight or obesity.
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Written by Colin Stuart.
Check out his fantastic astronomy newsletter here: https://colinstuart.substack.com.
Edited and animated by Siji Sheehan.
Narrated by David Kelly.
Thumbnail Art by Ettore Mazza.
Audio editing by Jack White and Peter Halstead.
Mastering by Craig Stevenson.
Extra animations by @ArtandContext (Manuel Rubio)
Extra animations by Jero Squartini https://www.fiverr.com/share/0v7Kjv using Manim — MIT License, © 2020–2023 3Blue1Brown LLC
A huge thanks to our Ho’oleilana Patreon supporters — James Keller, Unpunnyfuns, Ramsay Chambers, Matthew Williams and Mike Cumings, Jr.
Footage from Videoblocks, Artlist. Other footage from NASA and ESO.
Music from Epidemic Sound, Artlist, Silver Maple and Yehezkel Raz.
Images of scientists frequently from the AIP
Icons from The Noun Project.
Quantum Fluctuations by Derek Leinweber.
00:00 Introduction.
04:18 Will The Universe Go On Forever?
17:42 What Lingers In The Long Night?
33:20 What Would It Mean?
46:20 Everything Everywhere
Over the past decades, quantum scientists have introduced various technologies that operate leveraging quantum mechanical effects, including quantum sensors, computers and memory devices. Most of these technologies leverage entanglement, a quantum phenomenon via which two or more particles become intrinsically linked and share a unified quantum state, irrespective of the distance between them.
Friday, March 20, 2026: See our latest news and updates on NASA’s Artemis 2 moon rocket’s return to Launch Complex-39B.
Year 2023 face_with_colon_three
Scientists have figured out a way to detonate the ‘doors’ that lead to the heart of cancerous tumors, blowing them wide open for drug treatments.
The strategy works by triggering a ‘timer bomb’ on the cells that line a tumor’s associated blood vessels.
These vessels control access to the tumor tissue, and until they are opened, engineered immune cells can’t easily gain entry to the cancer to fight it off.
Year 2025 This could essentially end disease where the diseases would be edited off and the host repaired internally.
Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones.
Study: Switch-like gene expression modulates disease risk. Image Credit: gopixa / Shutterstock.
In a recent article published in Nature Communications, researchers analyzed methylomes, transcriptomes, and genomes from 943 individuals to characterize and identify genes that exhibit distinct on-off switches and explore their epigenetic and genetic regulation.
Majoros, Zhang, and Rahmati et al. identify a link between maternal autoimmunity and disrupted neuronal network development in the hippocampus of mice. In utero exposure to NMDA receptor autoantibodies impairs GABAergic signaling and early network synchrony in neonates, hindering the emergence of continuous hippocampal activity around eye opening.
Simulated lunar dirt can be turned into extremely durable structures, potentially paving the way to more sustainable and cost-effective space missions, a new study suggests. Using a special laser 3D printing method, researchers melted fake lunar soil—a synthetic version of the fine dusty material on the moon surface, called regolith simulant—into layers and fused it with a base surface to manufacture small, heat-resistant objects.
If utilized on the lunar surface, the material may help build sturdy, nontoxic habitats and tools for future astronauts, capabilities that would be vital to the NASA Artemis missions that aim to establish a long-term human presence on the moon by the end of the decade.
But to assess how well this new construction material may work in space, the team tested their fabrication process under a range of different environmental conditions, revealing that the overall quality of the material depends greatly on the surface onto which the soil is printed.
