Lifeboat Foundation: Safeguarding Humanity
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Synopsys is looking to add generative AI to its EDA tools to boost chip design productivity.

The company already uses a range of AI techniques in its tools from deep neural networks (DNNs) to recursive neural networks (RNNs). These are incorporated into the DSO.ai, VSI.ai and TSO.ai tools that have been used for well over 100 chip tapeouts.

Now the company is looking at the transformer network technologies used in generative AI (Gen-AI) to further enhance the tools says founder and retiring CEO Aart de Geus.

“We intend to harness Gen-AI capabilities into Synopsys.ai. We see this delivering further advances in design assistance, design exploration, and design generation,” said de Geus.

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Researchers have designed a molecule that kills blood cancer cells by tricking them into self-destructing, according to results of a new study. Experts say the molecule represents a new class of compounds that could have broad potential as cancer treatments.

Like a cyanide pill hidden in the teeth of a James Bond villain, human cells have a quick means of self-destruction if necessary. This natural safeguard is a way for the body to rid itself of old, damaged, or infected cells—including cancer cells.

But in many types of cancer, those means of self-destruction are subverted or blocked off. In some diffuse large B-cell lymphoma (DLBCL) tumors, for example, genes that orchestrate cell death are shut off by a protein called BCL6.

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What do pacemakers, prosthetic limbs, Iron Man and flu vaccines all have in common? They are examples of an old idea that’s been gaining in significance in the last several decades: transhumanism. The word denotes a set of ideas relating to the increasing integration of humans with their technologies. At the heart of the transhuman conversation, however, lies the oldest question of all: What does it mean to be human?

When talking about transhumanism, it’s easy to get lost because the definition is imprecise. “Transhumanism” can refer to the Transhumanist (with a capital T) movement, which actively pursues a technologically enhanced future, or an amorphous body of ideas and technologies that are closing the bio-techno gap, such as a robotic exoskeleton that enhances the natural strength of the wearer.

At Arizona State University, a diverse set of researchers has been critically examining transhumanism since 2004.

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Summary: New research delves into the distinctive human trait of sequential memory, setting us apart from bonobos. A recent study has also highlighted the joy in chasing passions over accomplishments. Groundbreaking discoveries show the human brain’s computational prowess, mirroring high-powered computers.

Additionally, the footprint of Big Tobacco is evident in the modern American diet through the promotion of hyperpalatable foods. Lastly, understanding the range of mind’s visualization abilities, from hyperphantasia to aphantasia, opens avenues for innovative treatments.

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Our current theory of evolution holds that all life on Earth originated from a single, simple life form billions of years ago. But what if that life did not originate on Earth? In this episode we’ll explore the theory of Panspermia, that origin of life might be extraterrestrial in origin, and that the abiogenesis of that origin life form we descend from might have descended from the sky in a comet or some other alien source. We will explore the impact this concept would have on the Fermi Paradox if true.
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Credits:
The Fermi Paradox & Panspermia.
Episode 171, Season 5 E05

Written by:
Isaac Arthur.

Editors:

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Quantum computing has provided new insights into a fundamental aspect of photochemical reactions that has previously proven difficult to study. The findings could improve scientists’ understanding of light-driven processes such as photosynthesis, smog formation and ozone destruction.

Photochemical processes occur when atomic nuclei and their electrons take on different configurations after absorbing a photon. Some of these reactions are guided by a quantum phenomenon called a conical intersection, where the potential energy surfaces that describe a molecule in its ground state and in its excited state converge. In these situations, quantum mechanical interference can prevent certain molecular transformations from taking place – a constraint known as a geometric phase. This limits the path that the reaction can take and affects the reaction outcome. The geometric phase has been known about since the 1950s, but due to the femtosecond timescales involved, it has never been directly observed in a molecular system.

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CRISPR-based genome editing has the potential to treat many human genetic diseases, but achieving stable, efficient and safe in vivo delivery remains a challenge. This Review assesses current delivery systems for genome editors—focusing on adeno-associated viruses and lipid nanoparticles—and highlights data from recent clinical trials. Emerging delivery systems and ongoing challenges in the field are discussed.

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