Lifeboat Foundation

Knowing that current methods to detect viruses and other biological markers of disease are effective, yet large and expensive (such as fluorescence microscopes), a team of researchers at the University of Tokyo (Tokyo, Japan) has developed and tested a miniaturized virus-scanning system that makes use of low-cost components and a smartphone. The researchers hope the system could aid those who tackle the spread of diseases faster, as current tools—while highly accurate at counting viruses—are too cumbersome for many situations, especially when rapid diagnosis is required.

The newly developed device, which scans biological samples for real viruses, is portable, low-cost, and battery-powered. Yoshihiro Minagawa from the University of Tokyo, who led the development, tested the device with viruses, but says it could also detect other biological markers.

“I wanted to produce a useful tool for inaccessible or less-affluent communities that can help in the fight against diseases such as influenza,” says Minagawa. “Diagnosis is a critical factor of disease prevention. Our device paves the way for better access to essential diagnostic tools.”

A humanized antibody from a recently-developed mouse model potently neutralizes SARS-CoV-2 variants by inhibiting membrane fusion.

On 30 January 2020 COVID-19 was declared a Public Health Emergency of International Concern (PHEIC) with an official death toll of 171. By 31 December 2020, this figure stood at 1 813 188. Yet preliminary estimates suggest the total number of global deaths attributable to the COVID-19 pandemic in 2020 is at least 3 million, representing 1.2 million more deaths than officially reported.

With the latest COVID-19 deaths reported to WHO now exceeding 3.3 million, based on the excess mortality estimates produced for 2020, we are likely facing a significant undercount of total deaths directly and indirectly attributed to COVID-19.

Continue reading “The true death toll of COVID-19” »

Researchers at Washington State University have discovered a new method to create renewable natural gas from sewage sludge.

Leukaemia patients were successfully treated with first-in-human “universal” CRISPR-edited T-cells by specialist researchers.

Even more daring, biology’s “mirror dimension” may be a springboard to engineer synthetic life forms that exist outside of nature, but are literal reflections of ourselves. To rephrase: building a mirror-image version of biology means rewriting the fundamental operating system of life.

Sound a bit too sci-fi? Let me explain. Similar to how our left hand can’t wear a right-hand glove, the building blocks of life—DNA, RNA, and proteins—are etched into specific 3D structures. Flip them around, as if reflected by a mirror, and they can no longer function inside the body. Scientists aren’t yet sure why nature picked just one shape out of two potential mirror images. But they’re ready to test it out.

A new study in Science made strides by reworking parts of the body’s protein-making machine into its mirror image. At the center is a structure called the ribosome, which intakes genetic code and translates it into amino acids—the Lego blocks for all proteins. The ribosome is an iconic cellular architecture, fused from two main molecular components: RNA and proteins.

Summary: Female mice who have not been pregnant or given birth show activation in the anterior cingulate cortex when they acquire maternal behaviors after exposure to pups. The findings reveal through repeated exposure to pups, virgin female mice are capable of learning maternal behaviors that resemble those of mothers following birth.

Source: Medical University of Vienna.

Various conditions such as postpartum depression or postpartum psychosis can lead to an alteration in maternal behavior and disrupt the mother-child bonding process.

THE most impressive designs for near-future Mars bases have finally been revealed.

These elaborate celestial plans are the difference between human life surviving on Mars – and thriving.

When it comes to planning how to live on a planet like Mars, 3D printing has provided scientists with the easiest way of navigating an environment that has similarities, but ultimately boasts a vastly different environment from Earth.

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Hello and welcome! My name is Anton and in this video, we will talk about unusual discoveries coming directly from within our mouths — biofilm complexity.
Links:
https://en.wikipedia.org/wiki/Biofilm.
https://www.pnas.org/doi/full/10.1073/pnas.2209699119
https://en.wikipedia.org/wiki/Quorum_sensing.
Slime: https://www.youtube.com/watch?v=spZwZLkMsYw.
Biofilm communication and bacterial cities: https://youtu.be/4M872c27bSc.
#biology #dentistry #biofilm.

Continue reading “Incredibly, Microbes Inside Our Mouths Turn Into a Superorganism That Moves Around” »