Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 29

Get the latest international news and world events from around the world.

Log in for authorized contributors

Solar System Colonization Strategies

Whether its pioneering spirit and an urge to explore or a chance to make a fortune or new life out in space, colonization of our solar system may pursue many strategies across many new worlds.

Start Forging New Worlds: https://www.worldanvil.com/isaac-arthur.
Join this channel to get access to perks:
/ @isaacarthursfia.
Visit our Website: http://www.isaacarthur.net.
Join Nebula: https://go.nebula.tv/isaacarthur.
Support us on Patreon: / isaacarthur.
Support us on Subscribestar: https://www.subscribestar.com/isaac-a… Group: / 1,583,992,725,237,264 Reddit: / isaacarthur Twitter: / isaac_a_arthur on Twitter and RT our future content. SFIA Discord Server: / discord Credits: Solar System Colonization Strategies Science & Futurism with Isaac Arthur Episode 316, November 11, 2021 Written, Produced & Narrated by Isaac Arthur Editors: A.T. Long Keith Blockus Sig’unnr Cover Art: Jakub Grygier https://www.artstation.com/jakub_grygier Graphics: Fishy Tree https://www.deviantart.com/fishytree/ Jarred Eagley Jeremy Jozwik https://www.artstation.com/zeuxis_of_… Katie Byrne Ken York / ydvisual Kris Holland of www.maficstudios.com Sam McNAmara Sergio Botero https://www.artstation.com/sboterod?f… Space Engine Music Courtesy of Epidemic Sound http://epidemicsound.com/creator.
Facebook Group: / 1583992725237264
Reddit: / isaacarthur.
Twitter: / isaac_a_arthur on Twitter and RT our future content.
SFIA Discord Server: / discord.

Credits:
Solar System Colonization Strategies.
Science & Futurism with Isaac Arthur.
Episode 316, November 11, 2021
Written, Produced & Narrated by Isaac Arthur.

Editors:
A.T. Long.
Keith Blockus.
Sig’unnr.

Cover Art:
Jakub Grygier https://www.artstation.com/jakub_grygier.

Graphics:

Continue reading “Solar System Colonization Strategies” | >

Megastructure Death

Megastructures of the future may range in size from cities to entire galaxies, and must be built to withstand damage and time, but how is this done and what happens when a megastructure dies?

Visit our sponsor, Brilliant: https://brilliant.org/IsaacArthur/
Join this channel to get access to perks:
https://www.youtube.com/channel/UCZFipeZtQM5CKUjx6grh54g/join.
Visit our Website: http://www.isaacarthur.net.
Join Nebula: https://go.nebula.tv/isaacarthur.
Support us on Patreon: https://www.patreon.com/IsaacArthur.
Support us on Subscribestar: https://www.subscribestar.com/isaac-arthur.
Facebook Group: https://www.facebook.com/groups/1583992725237264/
Reddit: https://www.reddit.com/r/IsaacArthur/
Twitter: https://twitter.com/Isaac_A_Arthur on Twitter and RT our future content.
SFIA Discord Server: https://discord.gg/53GAShE

Credits:
Megastructure Death.
Science & Futurism with Isaac Arthur.
Episode 308, September 16, 2021
Written, Produced & Narrated by Isaac Arthur.

Editors:
A.T. Long.
Curt Hartung.
Jason Burbank.
Jerry Guern.
Keith Blockus.

Cover Art:
Jakub Grygier https://www.artstation.com/jakub_grygier.

Graphics:

Continue reading “Megastructure Death” | >

Bringing the genetically minimal cell to life on a computer in 4D

This work represents a fundamental advance in understanding life’s basic principles. By building a cell from the bottom up—specifying every gene, protein, and reaction—researchers can test how life functions with minimal complexity. The simulation serves as a “digital twin” that allows scientists to probe questions impossible to address experimentally, such as how spatial organization affects cellular processes or how subtle parameter changes alter cell cycle timing.

Simulating the complete cell cycle of the minimal cell provides a platform to understand the progression of complete states over time. The spatial heterogeneity of the intracellular environment can strongly affect biochemical reactions that control phenotypes.

Mapping human brain cell type origin and diseases through single-cell transcriptomics

Wang P, Zhao D, Lachman HM, Zheng D. Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons. Transl Psychiatry. 2018;8:13. https://doi.org/10.1038/S41398-017-0058-6

Article PubMed PubMed Central Google Scholar

CD36-Fatty Acid-Mediated Metastasis via the Bidirectional Interactions of Cancer Cells and Macrophages

Tumour heterogeneity refers to the complexity of cell subpopulations coexisting within the tumour microenvironment (TME), such as proliferating tumour cells, tumour stromal cells and infiltrating immune cells.

Immune-microbiome coordination defines interferon setpoints in healthy humans

Now online! A comprehensive multi-omic analysis of healthy humans reveals two major axes of immunological variation characterized by interferon responses, one of which is coordinated with the microbiome and its metabolites and is stable over time within individuals.

Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome

Duan et al. systematically delineate the spatiotemporal dynamics and key regulators of pyroptosis during MASLD progression. Hepatocyte-specific Plagl2 deletion alleviates MASH by suppressing MYD88-mediated inflammasome activation and restoring metabolic homeostasis. Pyroptosis-driven IL-1β release promotes macrophage differentiation into a phagocytosis-enhanced, JAK/STAT-activated, NASH-associated phenotype.

Tinnitus Is Somehow Connected to a Crucial Bodily Function

Those who have never endured the relentless ringing of tinnitus can only dream of the torment. In fact, a bad dream may be the closest some get to experiencing anything like it.

The subjective sound, which can also be a hissing, buzzing, or clicking, is heard by no one else, and it may be present constantly, or may come and go.

Neuroscientists at the University of Oxford now suspect that sleep and tinnitus are closely intertwined in the brain.

/* */