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In the Lord of the Rings, there was “one ring to rule them all.” Now, a team of researchers is developing their own single ruler, an approach to CAR T-cell therapy that could treat all forms and types of blood cancer.

In experiments in mouse models of different blood cancers, the treatment rapidly eliminated tumors, including in mice with acute myeloid leukemia (AML), a difficult-to-treat type of blood cancer for which researchers have struggled to develop effective immunotherapies.

There was also no evidence of serious side effects in the animals. And, finally—and distinctly from the standard approach to current CAR T-cell therapies—it provided the mice with a healthy supply of new blood cells.

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Did you know that Einstein’s most important equation isn’t E=mc^2? Find out all about his equation that expresses how spacetime curves, with Sean Carroll.

Buy Sean’s book here: https://geni.us/AIAOUHn.
YouTube channel members can watch the Q&A for this lecture here: • Q&A: The secrets of Einstein’s unknow…

Become one of our YouTube members for early, ad-free access to our videos, and other perks: / @theroyalinstitution.

This lecture was recorded at the Ri on Monday 14 August 2023.

00:00 Einstein’s most important equation.
3:37 Why Newton’s equations are so important.
9:30 The two kinds of relativity.
12:53 Why is it the geometry of spacetime that matters?
16:37 The principle of equivalence.
18:39 Types of non-Euclidean geometry.
26:26 The Metric Tensor and equations.
32:22 Interstellar and time and space twisting.
33:32 The Riemann tensor.
37:45 A physical theory of gravity.
43:28 How to solve Einstein’s equation.
47:50 Using the equation to make predictions.
51:05 How its been used to find black holes.

The real Einstein’s Equation is part of general relativity, which relates the curvature of spacetime to the mass and energy distributed within it.

Continue reading “The secrets of Einstein’s unknown equation — with Sean Carroll” | >

On every count, nanoelectrofuel flow batteries appear to beat lithium-ion batteries for use in EVs and larger systems. Influit expects that its current generation of nanoelectrofuel, together with the entire ecosystem needed to produce, distribute, and recycle the fuel that the company is building around it, should cost $130/kWh when used in an EV. In comparison, lithium-ion batteries cost around $138/kWh. True, lithium-ion’s costs should drop below $100/kWh in a few years, but Influit expects its next-generation nanoelectrofuel to fall even further, to around $50 to $80/kWh. That next-gen system should have 5 times the energy density of present Li-ion systems.

Here’s what that means for an EV.

A typical EV battery today occupies about the same volume as would a flow battery with 400 liters of nanelectrofuel. If nanoparticles made up 30 percent of the weight of that fuel, the EV would have a range of only 105 km. Raise that to 40 percent, and the range would climb to 274 km. At 50 percent, it hits 362 km. And at 80 percent, it’s 724 km (450 miles). And that’s all assuming the flow battery’s tank remains the same size.

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NEW YORK (AP) — Nearly three years after rioters stormed the U.S. Capitol, the false election conspiracy theories that drove the violent attack remain prevalent on social media and cable news: suitcases filled with ballots, late-night ballot dumps, dead people voting.

Experts warn it will likely be worse in the coming presidential election contest. The safeguards that attempted to counter the bogus claims the last time are eroding, while the tools and systems that create and spread them are only getting stronger.

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The James Webb Space Telescope recently trained its sights on unusual and enigmatic Uranus, an ice giant that spins on its side. Webb captured this dynamic world with rings, moons, storms, and other atmospheric features—including a seasonal polar cap. The image expands upon a two-color version released earlier this year, adding additional wavelength coverage for a more detailed look.

With its exquisite sensitivity, Webb captured the dim inner and outer rings of Uranus, including the elusive Zeta ring—the extremely faint and diffuse ring closest to the planet. It also imaged many of the planet’s 27 known moons, even seeing some small moons within the rings.

In visible wavelengths as seen by Voyager 2 in the 1980s, Uranus appeared as a placid, solid blue ball. In infrared wavelengths, Webb is revealing a strange and dynamic ice world filled with exciting atmospheric features.

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Tesla recorded $500M+ in gross profit from its Energy and Services (Supercharging) segments in Q3 2023. Elon Musk noted how strong energy gross margins were on the call, and insinuated strength in these businesses will continue. I think this is a super exciting development for Tesla investors as the company can smooth out cyclicality in it’s automotive business with consistent profits from its Energy and Services.

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