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Surprising culprit leads to chronic rejection of transplanted lungs and hearts

Despite advances in the field of organ transplantation, long-term organ rejection that can become apparent a decade or more after a heart or lung transplant remains a common problem for patients. This chronic organ failure has long been attributed exclusively to the recipient’s immune system attacking the foreign organ over time.

Now, a study led by researchers at Washington University School of Medicine in St. Louis shows that chronic organ rejection may instead be triggered by the disruption of lymphatic vessels—an important drainage system throughout the body—from the donor organ rather than an attack by the patient’s immune system.

The study is published in Science Translational Medicine. It includes analyses of transplanted human organs with chronic rejection and mouse models of lung and heart transplantation.

Why Nobody’s Talking about Neuralink’s Progress

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Frequently distracted? Your brain rhythms may be to blame

Scientists may have new answers to why pop-ups or notifications grab our attention. Turns out our attention is on a cycle, shifting seven to 10 times per second. This rhythmic occurrence may be crucial for survival, as it prevents us from becoming overly focused on one thing in our environment. It could help us to see a car backing up in a parking lot while we search for where we parked, or to duck to avoid a low-hanging tree branch on a walk while watching a kid ride a bike.

However, these windows that shift our attention could also make us more susceptible to distractions, especially in modern times. As we live in a world surrounded by screens, digital alerts, and other visual stimuli, these frequent and innate windows for shifting attention may make it easier to be pulled away from a task.

“For our ancestors who had to continue to monitor the environment for predators while foraging for food, this was a beneficial trait,” said Ian Fiebelkorn, Ph.D., assistant professor of Neuroscience at the Del Monte Institute for Neuroscience at the University of Rochester and senior author of a study out in the journal PLOS Biology. “But in our modern environment, with laptops open in front of us and a smartphone nearby, rhythmically occurring windows for beneficial attentional shifts might also work against us. That is, rhythmically occurring windows for attentional shifts are also associated with increased susceptibility to distracting information.”

2D memristors could help solve AI’s energy problem

New generations of memristors could reliably store information directly within the molecular structures of graphene-like materials. In a new review published in Nanoenergy Advances, Gennady Panin of the Russian Academy of Sciences shows how these atomically thin materials are ideally suited for electrical circuits that mimic the function of our own brains—and could help address the vast power requirements of emerging AI technologies.

A memristor is a cutting-edge electrical component whose resistance depends on the amount of current that previously passed through it. Because it “remembers” this history even after charge is no longer flowing, it can store data when the power is switched off. In this way, memristors operate in a way remarkably similar to the neurons in our brains and the synapses connecting them.

With their fast response times, combined with simple, two-electrode structures that allow them to be packed into dense arrays, memristors are increasingly forming the building blocks of modern circuits—especially those designed for AI.

Nano-cage removes up to 98% of PFAS in tap water tests

Contamination of ground, surface and drinking water by perfluoroalkyl and polyfluoroalkyl substances (PFAS) affects millions of people worldwide. A promising new method developed by Flinders University scientists paves the way to help remove the most difficult-to-capture variants of these persistent pollutants from water.

The research team, led by Flinders ARC Research Fellow Dr. Witold Bloch, has discovered adsorbents that effectively capture PFAS, including short-chain forms that are especially difficult to remove using existing technologies.

The study, published in the Angewandte Chemie International Edition, showcases the use of a nano-sized molecular cage that acts as a highly selective “PFAS trap.”

Your car’s tire sensors could be used to track you

Researchers at IMDEA Networks Institute, together with European partners, have found that tire pressure sensors in modern cars can unintentionally expose drivers to tracking. Over a ten-week study, they collected signals from more than 20,000 vehicles, revealing a hidden privacy risk and highlighting the need for stronger security measures in future vehicle sensor systems.

Most modern cars are equipped with a Tire Pressure Monitoring System (TPMS), mandatory since the late 2000s in many countries for their contribution to road safety. This system uses small sensors in each wheel to monitor tire pressure and sends wireless signals to the car’s computer to alert the driver if a tire is underinflated.

However, the researchers found that these tire sensors also send a unique ID number in clear, unencrypted wireless signals, meaning that anyone nearby with a simple radio receiver can capture the signal, and recognize the same car again later. Most vehicle tracking today uses cameras that need clear visibility and line-of-sight to a car. TPMS tracking is different: tire sensors automatically send radio signals that pass through walls and vehicles, allowing small hidden wireless receivers to capture them without being seen.

A world first at the microscopic scale: Metamaterials that can shrink and expand on their own

Leiden physicists Daniela Kraft and Julio Melio have created soft structures that can take on different shapes without any external drive in their lab. They present their research on microscale metamaterials in Nature —a breakthrough that opens the door to smart, reconfigurable materials and microscopic robots.

“Metamaterials have completely changed the way we think about materials,” explains Professor of Experimental Physics Daniela Kraft. “In these systems, movements are no longer set by the material itself, but by the structure—the way particles are connected. We set out to create such functional structures at the microscopic scale. And we succeeded.”

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