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Light-guided ‘optovolution’ evolves proteins that switch states on schedule

EPFL researchers have developed a light-based method that can produce proteins that switch states, respond to signals, and even compute, using light and the cell cycle.

Evolution is biology’s powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature “select” the organism that performs best. Early farmers started taking advantage of evolution by interfering with natural selection and letting only the most productive livestock and crops mate.

In laboratories, researchers have developed methods for directed evolution of proteins, especially enzymes and antibodies, that are used in household detergents, medicine, and industry.

Scientists Spin Molecules Inside a Frictionless Superfluid for the First Time

A newly designed optical centrifuge allows scientists to control molecular rotation inside superfluid helium nano-droplets. Physicists have developed a new version of an optical centrifuge that can control how molecules rotate while they are suspended inside liquid helium nano-droplets. The advan

Scientists Map the Hidden Chemistry of Solar-Powered Catalysts

A new computational approach reveals how subtle structural changes in polyheptazine imides can dramatically influence their ability to convert sunlight into chemical energy. Photocatalysis offers a promising way to convert abundant sunlight into useful chemical energy. Among the materials attract

Rethinking the “Goldilocks Zone”: Astronomers May Have Been Looking for Life in the Wrong Places

A new study challenges the traditional boundaries of the habitable zone, showing that liquid water could exist on the dark sides of tidally locked planets or beneath thick ice on distant worlds. For decades, the search for alien life has been guided by a simple idea: find planets in the habitabl

Transparent Tribe Uses AI to Mass-Produce Malware Implants in Campaign Targeting India

The Pakistan-aligned threat actor known as Transparent Tribe has become the latest hacking group to embrace artificial intelligence (AI)-powered coding tools to strike targets with various implants.

The activity is designed to produce a “high-volume, mediocre mass of implants” that are developed using lesser-known programming languages like Nim, Zig, and Crystal and rely on trusted services like Slack, Discord, Supabase, and Google Sheets to fly under the radar, according to new findings from Bitdefender.

“Rather than a breakthrough in technical sophistication, we are seeing a transition toward AI-assisted malware industrialization that allows the actor to flood target environments with disposable, polyglot binaries,” security researchers Radu Tudorica, Adrian Schipor, Victor Vrabie, Marius Baciu, and Martin Zugec said in a technical breakdown of the campaign.

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