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Category: life extension – Page 11

Rejuvenation And Dramatic Lifespan Extension Is Here!

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links/Affiliates:
Blood testing (where I get the majority of my labs): https://www.ultalabtests.com/partners/michaellustgarten.

Blood testing with LifeExtension.com: https://www.anrdoezrs.net/click-101614996-15750394

At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten.
Use Code: CONQUERAGING At Checkout.

Clearly Filtered Water Filter: https://get.aspr.app/SHoPY

Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ6…M0&irgwc=1

Continue reading “Rejuvenation And Dramatic Lifespan Extension Is Here!” | >

Dietary Patterns and Indicators of Cognitive Function

Greater adherence to the DASH diet, plant-based dietary patterns, or diets with lower hyperinsulinemia and inflammation was associated with lower risk of subjective cognitive decline and better cognitive function in adults.

Question Are healthy dietary patterns associated with lower risk of subjective cognitive decline and better objectively measured cognitive function?

Findings In this cohort study performing a systematic evaluation of 6 dietary patterns among 159 347 participants, greater adherence to a healthy diet, exemplified by the Dietary Approaches to Stop Hypertension (DASH) diet, was associated with lower risk of subjective cognitive decline and better objectively measured cognitive function. The associations were most pronounced when the diet was followed during midadulthood (ages 45–54 years).

Meaning Results suggest that a healthy diet, such as the DASH diet, was associated with early indicators of cognitive aging, which underscores the importance of a healthy diet for maintaining long-term cognitive health.

BREAKTHROUGH 100% Life Extension Achieved in Mouse Study

Immorta Bio just doubled the lifespan of mice using a first-in-class senolytic immunotherapy called SenoVax combined with personalized stem cells from their StemCellRevivify platform. In this deep dive, I break down exactly how it works, why it matters, and what it means for the future of human aging.

SenoVax is a vaccine that trains your immune system to hunt down and destroy senescent cells — the \.

Telomere-to-telomere assembly detects genomic diversity in Canadian strains of Borrelia burgdorferi

Amin et al. present telomere-to-telomere assemblies of nine Borrelia burgdorferi strains from Canada, uncovering the diversity at chromosome ends and plasmid profiles. They identify an lp28-1a plasmid subtype and detect plasmid-chromosome recombination, offering insights into genomic plasticity and potential mechanisms of adaptation in Borrelia.

Engineered immune therapy could help fight brain aging

Researchers at Stanford University engineered a modified version of the immune protein interleukin-10 (IL-10) that retains only its anti-inflammatory properties while eliminating its pro-inflammatory ones. When injected into aged mice, this modified protein stimulated the growth of new neurons and improved performance on memory and learning tasks, such as maze navigation and object recognition. The study, published in Immunity, suggests that age-related cognitive decline is linked to the accumulation of exhausted T-lymphocytes in the brain, chronic inflammation, and impaired microglial function — all of which reduce neurogenesis. The findings indicate that selectively modulating immune signaling could open new avenues for treating neurodegenerative diseases. The team plans to further investigate the protein’s mechanisms and explore ways to target specific cell types more precisely to minimize potential side effects.

A modified immune protein developed by Stanford researchers points to a novel strategy for combating age-related cognitive decline.

Technology is NOT Enough!

Fifteen years ago, I wrote something that annoyed many techno-optimists.

Ten years ago, I filmed it as a podcast.

Today it feels less controversial — and more urgent.

Technology is NOT Enough.

We have the science to feed everyone. We have the tech to provide clean water. We understand climate change. We know how to reduce suffering.

And yet we don’t act.

Continue reading “Technology is NOT Enough!” | >

The 5 Foods Every 100-Year-Old Ate Daily (Blue Zones Diet Breakdown)

The controversial diet truth backed by 155 dietary surveys across 90 years that food scientists don’t want you to know.

Dan Buettner exposes why meta-analyses prove most nutritional debates wrong and reveals what centenarians actually ate as children to live past 100.

The peasant food formula that’s cheaper than a hamburger, 50 times more nutrient dense, and leaves you completely satisfied.

Plus why the 15 countries with the highest life expectancy all eat white rice daily.

Dan Buettner is a New York Times bestselling author, National Geographic Fellow, and co-producer of the Emmy Award winning Netflix series Live to 100: Secrets of the Blue Zones.

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