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Category: health – Page 6

Exercise and the Organ-Brain Axis: Regulation of Neurological Disorders by Emerging Exerkines

Research on exercise and brain disorders has traditionally focused on its direct regulatory effects on neurons and synapses, neglecting peripheral organ-mediated pathways. To address this gap, this review proposes the novel concept of the “multi-organ-brain axis.” This concept posits that during brain disorders, functional alterations in peripheral organs such as skeletal muscle, heart, liver, adipose tissue, and spleen can disrupt metabolic and immune homeostasis, thereby bidirectionally modulating brain function via signaling molecules and metabolites.

Hackensack Meridian John Theurer Cancer Center Archives

Georgetown Lombardi, Washington’s only National Cancer Institute-designated Comprehensive Cancer Center, serves as the research engine for MedStar Health, Georgetown University’s clinical partner. Georgetown Lombardi is also an NCI-recognized research consortium with John Theurer Cancer Center of Hackensack Meridian Health in Bergen County, New Jersey.

They have a blog with alot of useful cancer information you can share. There is info about them circulating about cancer vaccines and clinical trials. Check em out:

(You can repost their posts or contact them to recieve information from them directly. Lombardi Comprehensive Cancer Center 3,800 Reservoir Rd. NW Washington D.C. 20,057 Phone: 202−444−2223)

Routine AI assistance may lead to loss of skills in health professionals who perform colonoscopies

The introduction of artificial intelligence (AI) to assist colonoscopies is linked to a reduction in the ability of endoscopists (health professionals who perform colonoscopies) to detect precancerous growths (adenomas) in the colon without AI assistance, according to a paper published in The Lancet Gastroenterology & Hepatology.

Colonoscopy enables detection and removal of adenomas, leading to prevention of bowel cancer. Numerous trials have shown the use of AI to assist colonoscopies increases the detection of adenomas, generating much enthusiasm for the technology. However, there is a lack of research into how continuous use of AI affects endoscopist skills, with suggestions it could be either positive, by training clinicians, or negative, leading to a reduction in skills.

Author Dr. Marcin Romańczyk, Academy of Silesia (Poland), says, To our knowledge, this is the first study to suggest a negative impact of regular AI use on health care professionals’ ability to complete a patient-relevant task in medicine of any kind.

The overlapping global distribution of dengue, chikungunya, Zika and yellow fever

Arboviruses transmitted by Aedes mosquitoes have an expanding global distribution and identifying areas at risk is important for public health planning. Here, the authors present global disease maps for dengue, chikungunya, Zika and yellow fever through a multi-disease ecological niche modelling approach.

Invisible Polymer Film Could Revolutionize Smart Devices with Metal-Like Conductivity

From smartphones and smartwatches to medical biosensors, the demand for thinner, lighter, and more powerful electronic components continues to grow. Now, scientists at La Trobe University have developed a groundbreaking invisible polymer film that conducts electricity as effectively as metals, yet is flexible, durable, and scalable for mass production. This innovation could transform not only consumer electronics but also advanced health monitoring devices and wearable technology.

The Breakthrough: Tethered Dopant Templating

For decades, conductive polymers — synthetic materials capable of carrying an electrical current — have been hailed as a promising alternative to metals in electronics. However, they have struggled to achieve the necessary combination of thinness, transparency, conductivity, and durability required for high-performance devices.

Overlooked microproteins could treat obesity and metabolic disorders

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 diabetes, cardiovascular diseases, chronic kidney disease, and cancers.

Current treatment options include lifestyle interventions, bariatric surgery, and GLP-1 drugs like Ozempic or Wegovy, but many patients struggle to access or complete these treatments or to maintain their weight loss afterward.

Salk Institute scientists are looking for a new treatment strategy in microproteins, an understudied class of molecules found throughout the body that play roles in both health and disease.

Sleep disruption damages blood vessels in brain and may increase dementia risk: study

A new study reveals that fragmented sleep causes cellular damage to the brain’s blood vessels, providing further evidence to suggest that sleep disruption predisposes the brain to dementia.

The research, published in the journal Brain, is the first to offer cellular and molecular evidence that sleep disruption directly causes damage to brain blood vessels and blood flow.

“We found that individuals who had more fragmented sleep, such as sleeping restlessly and waking up a lot at night, had a change in their balance of pericytes—a brain blood vessel cell that plays an important role in regulating brain blood flow and the entry and exit of substances between the blood and the brain,” said Andrew Lim, principal investigator of the study and a sleep neurologist and scientist at Sunnybrook Health Sciences Centre.

Post-prandial hyperlipidaemia impairs systemic vascular function and dynamic cerebral autoregulation in young and old male adults

Dietary fat is an important part of our diet. It provides us with a concentrated source of energy, transports vitamins and when stored in the body, protects our organs and helps keep us warm. The two main types of fat that we consume are saturated and unsaturated (monounsaturated and polyunsaturated), which are differentiated by their chemical composition.

But these fats have different effects on our body. For example, it is well established that eating a meal that is high in saturated fat, such as that self-indulgent Friday night takeaway pizza, can be bad for our blood vessels and heart health. And these effects are not simply confined to the heart.

The brain has limited energy stores, which means it is heavily reliant on a continuous supply of blood delivering oxygen and glucose to maintain normal function.

One of the ways the body maintains this supply is through a process known as “dynamic cerebral autoregulation”. This process ensures that blood flow to the brain remains stable despite everyday changes in blood pressure, such as standing up and exercising. It’s like having shock absorbers that help keep our brains cool under pressure.

But when this process is impaired, those swings in blood pressure become harder to manage. That can mean brief episodes of too little or too much blood reaching the brain. Over time, this increases the risk of developing conditions like stroke and dementia.

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