Can cannabidiol (CBD) serve as a mouthwash to combat gingivitis? This is what a recent study published in the Journal of Clinical Medicine hopes to address | Cannabis Sciences
Category: health – Page 3
How can young adults address potential heart risks later in life as they mature into adulthood? This is what a recent study published in the Journal of the | Cardiology
Tesla is preparing to launch its robo taxi in June, leveraging its unique autonomy and data advantages to navigate challenges such as new tariffs and production shifts, while positioning itself for significant growth amid declining competitor viability ## Questions to inspire discussion ## Tesla’s Robo Taxi Service.
🚕 Q: When and where is Tesla launching its robo taxi service? A: Tesla’s robo taxi service is set to launch in Austin, Texas in June 2025, with plans for a nationwide rollout in the US later that year.
🏎️ Q: What vehicles will be eligible for Tesla’s robo taxi service? A: The service will be available on all vehicles equipped with Full Self-Driving (FSD) capability, including existing Model 3 and Model Y, not just the upcoming Cybertruck.
💰 Q: How will Tesla’s robo taxi network economics work? A: The economics will be based on cost per mile, factoring in low capital costs of Tesla EVs and low power consumption of their onboard autonomy systems.
📊 Q: What competitive advantage does Tesla have in the robo taxi market? A: Tesla’s existing fleet of billions of miles of deployed vehicles and hundreds of thousands of users provide a massive data advantage for improving and assessing the service. ## Tariffs and Supply Chain.
🏭 Q: What is Tesla’s supply chain strategy? A: Tesla aims to build cars where sold for environmental reasons, which is considered best practice in network design but extremely difficult to implement.
Microbial micronutrient sharing, gut redox balance and keystone taxa as a basis for a new perspective to solutions targeting health from the gut
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The first couple of months of life is a critical window for microbiome development. Several factors, such as mode of delivery, diet, environment, and the use of antibiotics, shape a child’s gut microbiota, which can have a profound impact on childhood development and lifelong health. For example, recent studies suggest that infants whose microbiome development is disrupted via cesarean section delivery, early antibiotic use, limited breastfeeding, or other factors are at greater risk for asthma and allergies, respiratory infections, inflammatory bowel disease (IBD), type 1 diabetes, and obesity. Citation 14, Citation 15 The assembly of the infant microbiome is first determined by maternal – infant exchanges of microbiota. Citation 16 Therefore, optimizing the maternal microbiome during pregnancy is likely part of a comprehensive approach to protect and promote the fetus’s health and provide the newborn with a specific microbial inoculum at birth. Citation 14, Citation 17 After birth, maternal breast milk promotes the colonization and maturation of the infant’s gut microbiome. Human milk contains a high concentration of indigestible glycans, known as HMOs which can act as growth substrates for beneficial Bifidobacteria to support the early founder strains of the infant microbiome. Citation 18, Citation 19 In addition, HMOs extert several microbiome-independent mechanism such as serving as decoy receptors to effectively block the attachment of pathogenic bacteria and directly interacting with various receptors. Citation 20 The infant microbiome evolves and diversifies further throughout life in response to whether an infant is breastfed, or formula-fed and which type of formula is used. The weaning period (i.e. the introduction of solid food at around 4–12 months) represents another important window of opportunity to positively impact the development of the microbiome as the bacterial community needs to adapt to digest dietary fibers. Studies linking low gut microbial diversity and the lack of specific bacteria to atopic dermatitis emphasize the first 18 month as a critical window period. Citation 21 Complete gut colonization then occurs within approximately 3 years of life and plays an essential role in further digestion, immunity and neuroendocrine pathway development. Citation 22, Citation 23 In cases where antibiotic treatment is necessary, biotic supplements (i.e. pre, pro, syn or postbiotics) have been shown to lessen the deleterious impact of antibiotics on the infant gut microbiome. Citation 24, Citation 25
In healthy adults, the gut microbiome is fully developed and designed to maintain overall balance while promoting its own survival against environmental stressors, with microorganisms engaging in complex interactions. Recent high-resolution studies examining microbiome composition before, during, and after antibiotic use at the individual gene x strain level demonstrate the remarkable adaptability or ‘fitness’ of gut microbial ecosystems. Citation 26, Citation 27 A healthy and fully functional ecosystem primarily aims to preserve its balance, with ecological diversification playing a crucial role in shaping the genetic structure of resident populations to defend against competition and external disruptors and stressors. Citation 27, Citation 28 Thus, intestinal bacterial ecosystems seem to carry an inherent ecological resilience helping to protect both, themselves and as a consequence their host’s health. This resilience seems to be driven by two main factors: a more diverse microbiome appears generally better at preserving its own balance; Citation 29, Citation 30 and 2) a highly collaborative and interdependent nature of microbial communities seems to play a key role in ecological resilience. In a healthy state, different species work together in a balanced and mutually beneficial way through mechanisms like crossfeeding of various microbial nutrients beyond SCFAs and other forms of metabolic cooperation to stabilize bacterial communities under varying environmental conditions. Citation 31 Understanding these mechanisms across all life stages, from infancy to adulthood to old age, while accounting for the variability in adult microbiome profiles shaped by factors such as genetics, diet, lifestyle, and environmental exposures Citation 32–35 will likely enable the design of better-tolerated and more precise interventions. These interventions could holistically target the functionality of microbiome networks rather than focusing solely on individual species or strains and, thus, allow to tap into the endogenous biochemical pathways that act to maintain bacterial homeostasis.
The large diversity of the adult microbiome, however, presents a notable challenge. A previous comprehensive investigation involving over 1,000 healthy individuals from diverse ancestral backgrounds living in shared environments provided interesting insights. It showed that genetic ancestry has minimal influence on gut microbiome composition. Instead, notable similarities were found in the microbiomes of unrelated individuals sharing the same household with over 20% of the differences in microbiome composition between individuals attributed to factors such as habitual diet, medication use, and anthropometric measurements. Citation 36 This is supported by findings from controlled-feeding studies in humans Citation 35 Citation 37 For example, microbiome composition changed detectably within 24 h of initiating a high-fat/low-fiber vs. a low-fat/high-fiber diet Citation 37 despite entrotype stability.
In a new paper, researchers at North Carolina State University show proof of concept for a system that—in a single cycle—actively removes microplastics from water.
The findings, described in the journal Advanced Functional Materials, hold the potential for advances in cleansing oceans and other bodies of water of tiny plastics that may harm human health and the environment.
“The idea behind this work is: Can we make the cleaning materials in the form of soft particles that self-disperse in water, capture microplastics as they sink, and then return to the surface with the captured microplastic contaminants?” said Orlin Velev, the S. Frank and Doris Culberson Distinguished Professor of Chemical and Biomolecular Engineering at NC State and corresponding author of the paper.
Everything the brain does—from storing memories to interpreting sights to regulating emotions—requires energy, all produced by cellular organelles called mitochondria.
However, surprisingly little is known about the distribution and diversity of the brain’s tiny energy processors and how they influence brain health. For instance, how many mitochondria does the brain have? Are they uniformly distributed across the whole brain? Are all brain mitochondria the same? Do changes in the brain’s mitochondria affect mood, cognition, and the development of neurological and psychiatric conditions?
To begin answering these and other questions, Columbia University researchers have created MitoBrainMap, the first-ever atlas of the brain’s mitochondria.
Changes in the heart might mean more than just cardiovascular risk – they could also signal early shifts in brain health.
A large meta-analysis found that even subtle heart problems, like issues with how the heart pumps or relaxes, are linked to smaller brain volumes, particularly in areas related to memory.
Heart Issues May Signal Early Dementia Risk.
Every year, millions of tires end up in landfills, creating an environmental crisis with far-reaching consequences. In the United States alone, over 274 million tires were scrapped in 2021, with nearly 20% of them being discarded in landfills. The accumulation of these waste materials presents not only a space issue but also introduces environmental hazards, such as chemical leaching and spontaneous combustion.
While pyrolysis—a process that chemically recycles rubber through high-temperature decomposition—is widely used, it generates harmful byproducts like benzene and dioxins, posing health and environmental risks.
A study titled “Deconstruction of Rubber via C–H Amination and Aza-Cope Rearrangement,” published in Nature, introduces a novel chemical method for breaking down rubber waste. This technique utilizes C–H amination and a polymer rearrangement strategy to transform discarded rubber into valuable precursors for epoxy resins, offering an innovative and sustainable alternative to traditional recycling methods.
NASA’s Parker Solar Probe just screamed past the Sun for the 23rd time, once again matching its own records for closest approach and fastest human-made object. Zooming through space at 430,000 mph and skimming just 3.8 million miles from the solar surface, the probe is in perfect health and sendi
To prevent similar incidents from reoccurring in the future, Cloudflare has improved credential logging and verification and now mandates the use of automated deployment tooling to avoid human errors.
The company is also updating standard operating procedures (SOPs) to require dual validation for high-impact actions like credential rotation and plans to enhance health checks for faster root cause detection.
Cloudflare’s R2 service suffered another 1-hour long outage in February, which was also caused by a human error.