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Category: health – Page 147

Scientists at University of Florida (UF) Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored the health of neurons in the lab and rescued mice with the disease.

The potential medication is described this week in the scientific journal Proceedings of the National Academy of Sciences. It is designed to be taken as a pill or an injection, said the lead inventor, professor Matthew Disney, Ph.D., chair of the UF Scripps chemistry department. Importantly, experiments showed that the compound is small enough to cross the blood-brain barrier, a hurdle other approaches have failed to clear, he said.

Amyotrophic lateral sclerosis, or ALS, progressively destroys neurons that control muscles, leading to worsening muscle loss and eventually death. The mutation, a leading cause of inherited ALS, is referred to as “C9 open reading frame 72,” or C9orf72. This mutation also leads to one form of frontotemporal dementia, a brain disease that causes the brain’s frontal and to shrink, resulting in changes in personality, behavior and speech, ultimately resulting in death.

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In space — Recent (China Manned Space Agency — No access Chinese mainland) 1. Various of Shenzhou-14 astronaut Cai Xuzhe unpacking packages 2. Various of Shenzhou-14 crew checking facilities, opening boxes and inspecting equipment 3. Shenzhou-14 crew installing and trying out microgravity resistance exercise device 4. Shenzhou-14 astronaut Liu Yang exercising with microgravity resistance exercise device.

The Shenzhou-14 astronauts have completed several missions over the last two weeks, including the installation of equipment in the work area of the Mengtian lab module which they entered for the first time on Nov. 3. Among the scientific and basic living equipment, the astronauts have also set up a small home gym to help them stay fit. The crew members-Chen Dong, Liu Yang and Cai Xuzhe can now keep fit in the lab with a special microgravity resistance exercise device similar to a rowing machine with which astronauts can do squats, heel lifts, hard pulls, rowing and shoulder exercise. Resistance exercise is especially important for astronauts living in zero gravity conditions which can rapidly reduce muscle mass and bone density.

On Sunday, the trio entered the Tianzhou-5 cargo craft to fetch supplies for the Tiangong space station.

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Researchers at Karolinska Institutet in Sweden have identified the bacteria most commonly found in severe oral infections. Few such studies have been done before, and the team now hopes that the study can provide deeper insight into the association between oral bacteria and other diseases. The study is published in Microbiology Spectrum.

Previous studies have demonstrated clear links between and , such as cancer, , diabetes and Alzheimer’s disease. However, there have been few identifying which occur in infected oral-and maxillofacial regions. Researchers at Karolinska Institutet have now analyzed samples collected between 2010 and 2020 at the Karolinska University Hospital in Sweden from patients with severe oral infections and produced a list of the most common bacteria.

This was a collaborative study that was performed by Professor Margaret Sällberg Chen and adjunct Professor Volkan Özenci’s research groups.

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A study of physiological responses of college-age Overwatch players found that many skilled players tend to start the game with elevated physiological stress responses, adjusting them during gameplay. The physiological stress responses of low skill players, in contrast, tend to increase as the game progresses. The study was published in the Journal of Strength and Conditioning Research.

Competitive electronic gaming or eSport is gaining traction as a recognized sport. The rise of eSports into a multi-billion dollar industry has been attributed to the emergence of streaming platforms and advertisement revenues and high-values sponsorships that came with them. eSports are one of the 24 competitive sports included in the 2022 Asian games held in Hangzhou, China.

Following their rise in popularity, scientists have become interested in studying eSports athletes to understand the stress related to participating in eSports both in competitive and noncompetitive settings. First studies focused on health concerns, given the sedentary nature of eSports, and primarily studied players of League of Legends (LOL) as one of the most popular eSports games at the time.

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November is Stomach Cancer Awareness Month, which makes this a good time to learn more about treating stomach cancer.

More than 26,000 people in the U.S. will be diagnosed with stomach cancer this year, and more than 11,000 people will die of the disease, according to the American Cancer Society. Stomach cancer accounts for about 1.5% of all new cancers diagnosed in the U.S. each year.

Stomach cancer, also known as gastric cancer, can affect any part of the stomach. In most of the world, stomach cancers form in the main part of the stomach. In the U.S., stomach cancer is more likely to affect the area where the esophagus meets the stomach. Where the cancer occurs in the stomach is one factor health care professionals consider when determining treatment options.

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It’s difficult to trace the epidemiology since the patient didn’t travel, the mutations in the viruses are small and international travel in and out of New York is heavy, he said.

“With a single case there’s no way to know exactly how many infections there were between the vaccine vial and the paralyzed person,” Oberste said.

It’s unlikely public health authorities will figure out the origin of the virus that paralyzed the patient in New York, Oberste said. Dozens of countries around the world — primarily in Africa, the Middle East and South Asia — are still using oral vaccines that contain the Sabin Type 2 strain.

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They then used QUARTZ to analyze retinal images from 7,411 more people, these aged 48 to 92, and combined this data with information about their health history (such as smoking, statin use, and previous heart attacks) to predict their risk of heart disease. Participants’ health was tracked for seven to nine years, and their outcomes were compared to Framingham risk score (FRS) predictions.

A common tool for estimating heart disease risk, the FRS looks at age, gender, total cholesterol, high density lipoprotein cholesterol, smoking habits, and systolic blood pressure to estimate the probability someone will develop heart disease within a given span of time, usually 10 to 30 years.

The QUARTZ team compared their data to 10-year FRS predictions and said the algorithm’s accuracy was on par with that of the conventional tool.

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A University of Maryland researcher and colleagues found that the fungus Metarhizium robertsii removes mercury from the soil around plant roots, and from fresh and saltwater. The researchers also genetically engineered the fungus to amplify its mercury detoxifying effects.

Mercury pollution of soil and water is a worldwide threat to public health. This new work suggests Metarhizium could provide an inexpensive and efficient way to protect crops grown in polluted areas and remediate -laden waterways.

The study, which was conducted by UMD professor of entomology Raymond St. Leger and researchers in the laboratory of his former post-doctoral fellow, Weiguo Fang (now at Zhejiang University in Hangzhou, China), was published in Proceedings of the National Academy of Sciences (PNAS) on November 14, 2022.

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