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Specifically, the researchers examined how THC administered through edibles, a common consumption method, influenced epigenetic changes in crucial areas for fetal development, including the placenta, fetal lung, brain, and heart.


In recent years, the popularity and availability of cannabis has grown significantly, with various consumption methods like edibles gaining traction. However, alongside this trend, there has been a worrisome increase in cannabis use among pregnant women. Unfortunately, our understanding of the detailed effects of using cannabis during pregnancy on the developing child remains limited. Because normal fetal development relies on the crucial process of epigenetic regulation and gene expression modification, it has been suggested that studying the molecular changes linked to cannabis exposure during pregnancy could provide important insights.

To gain a better understanding of the effects of cannabis use during pregnancy, researchers from the Oregon Health & Science University (OHSU) conducted a unique preclinical study that focused on investigating the epigenetic impact of THC, the main active component in cannabis, on fetal development and future health outcomes. The study’s findings were published in the journal Clinical Epigenetics.

With the increasing prevalence of cannabis use, there is a common perception that it is safe. As a result, more pregnant women are turning to cannabis, particularly during the first trimester, to relieve symptoms like morning sickness. However, early pregnancy is a critical time when the developing fetus is most susceptible to environmental factors.

The Struengmann brothers’ agreement Monday to lead the purchase of a hand-sanitizer maker owned by EQT AB alongside other investors marks at least the sixth major deal involving the billionaire twins and the Swedish private equity firm within the past decade, according to data compiled by Bloomberg.

The deal for EQT’s Schuelke & Mayr GmbH values the Norderstedt, Germany-based company at about €1.4 billion ($1.5 billion), people with knowledge of the matter have said, asking not to be identified discussing confidential information. Financial details weren’t disclosed. The sale is expected to close in the final quarter of 2023, according to a news release Monday.

A representative for the Struengmanns didn’t respond to a request for comment. The 73-year-old brothers are together worth about $24 billion, according to the Bloomberg Billionaires Index.

Using machine learning, the system could warn us about the emergence of dangerous virus variants in the future and allow us to prepare in advance.

We all know how devastating the COVID-19 pandemic has been – and it could have been even worse if not for the efforts of scientists and health workers around the world. But what if we could get a heads-up on the next most dangerous variants of a virus before they become a global threat?

Well, a new AI system can just do that. It can warn us about the emergence of dangerous virus variants in future pandemics, according to a study by scientists from Scripps Research and Northwestern University in the US.

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Health experts warn that rotting bodies could risk major disease outbreaks, particularly as Sudan approaches cholera season Thousands of corpses are rotting on the streets of Khartoum, the capital of Sudan, as power outages have left morgues at breaking point, according to Save The Children. Doctors have warned that the decomposing bodies could risk major disease outbreaks, particularly as Sudan meets its cholera season.

As much as we may love them, cats are major reservoirs of zoonotic infections, and their bites and scratches can pose a serious threat to our health. It’s a sad truth that one UK-based man found out the hard way after he was bitten by a stray cat and contracted an extensive soft tissue infection caused by a species of bacteria that had never been described before.

A case report describing the incident details how, back in 2020, the 48-year-old man turned up at the emergency department presenting with a painful, swollen hand. Eight hours earlier, he had been bitten several times by a feral cat. Doctors initially cleaned and dressed the man’s wounds, before giving him a tetanus shot and sending him on his way with a course of antibiotics.

However, within 24 hours he was back, with an intensifying infection in his left little and right middle fingers, as well as both forearms. Again, the area was cleaned, and this time, the damaged tissue was surgically removed and intravenous antibiotics were administered. After five days of oral antibiotics, he made a full recovery.

An important objective of medical research is to identify the underlying molecular mechanisms of human brain health and diseases.

This objective has been predominantly achieved through observational studies of gene expression in human brain tissues obtained from post-mortem brain donors for their analysis. Importantly, many of these studies are based on the assumption that gene expression in the post-mortem human brain is an exact representation of gene expression in the living human brain.

A recent study published on the medRxiv preprint server challenges this assumption by comparing human prefrontal cortex gene expression between living and post-mortem samples.

A recent study posted to the medRxiv preprint server investigates the association between the circulating proteome and brain health.

Study: The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses. Image Credit: Abduramanova Elena / Shutterstock.com.

*Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information.