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Bactericidal nanomachine: Researchers reveal the mechanisms behind a natural bacteria killer

In a study published in Nature, a UCLA-led team of researchers describe how the nanomachine recognizes and kills bacteria, and report that they have imaged it at atomic resolution. The scientists also engineered their own versions of the nanomachine, which enabled them to produce variations that behaved differently from the naturally occurring version.

Their efforts could eventually lead to the development of new types of antibiotics that are capable of homing in on specific species of microbes. Drugs tailored to kill only a certain species or strain of bacteria could offer numerous advantages over conventional antibiotics, including lowering the likelihood that bacteria will develop resistance. In addition, the tailored drugs could destroy harmful cells without wiping out beneficial bugs in the gut microbiome, and they could eventually offer the possibilities of being deployed to prevent bacterial infections, to kill pathogens in food and to engineer human microbiomes so that favorable bacteria thrive.

The particle in the study, an R-type pyocin, is a protein complex released by the bacterium Pseudomonas aeruginosa as a way of sabotaging microbes that compete with it for resources. When a pyocin identifies a rival bacterium, it kills the bacterium by punching a hole in the cell’s membrane. P. aeruginosa, frequently a cause of hospital-acquired illness, is found in soil, in water and on fresh produce. The germ is commonly studied and its biology is well understood.

No evidence COVID-19 transmits through food or packaging

AMES, Iowa — Over the past month, false information about COVID-19 and food and food packaging has been reported in the media, websites and blogs, and shared through social media, note food safety and nutrition and wellness specialists with Iowa State University Extension and Outreach. Angela Shaw, Anirudh Naig, and Shannon Coleman want Iowans to know there is no evidence that COVID-19 is transmitted through food and food packaging.

Shaw is a food safety state specialist and associate professor in the ISU Department of Food Science and Human Nutrition. Naig is a food safety state specialist and associate professor in the ISU Department of Apparel, Events, and Hospitality Management. Coleman is an assistant professor and nutrition and wellness state specialist in the ISU Department of Food Science and Human Nutrition.

COVID-19: Teenage Muslim boy from Lucknow “beaten” for buying biscuits, dies

A teenaged Muslim boy from Lucknow who was allegedly beaten up by policemen while he was trying to buy food has succumbed.

The slain has been identified as Mohammad Rizwan, he has become the first fatality from purported police high-handedness in enforcing the lockdown in Uttar Pradesh.

Rizwan’s father, Mohammed Israil, said his son had felt very hungry on Thursday night.

Drones Use Radio Waves to Recharge Sensors While in Flight

Here’s another neat thing drones can do—beam power across the sky to recharge sensors in hard-to-reach places.


Remote sensors play a valuable role in collecting data—but recharging these devices while they are scattered over vast and isolated areas can be tedious. A new system is designed to make the charging process easier by using unmanned aerial vehicles (UAVs) to deliver power using radio waves during a flyby. A specialized antenna on the sensor harvests the signals and converts them into electricity. The design is described in a study published 23 March in IEEE Sensors Letters.

Joseph Costantine and his colleagues at the American University of Beirut, in partnership with researchers at the Institute of Electronics, Computer, and Telecommunications Engineering in Italy, were exploring ways to remotely charge sensors using radio frequency waves (the same form of energy used to transmit Wi-Fi). However, a major challenge was that the source of the radio waves must be fairly close to the sensor in order to sufficiently charge it.

This prompted the researchers to consider the use of UAVs, which could soar over each sensor. “In addition, a UAV can follow an optimized trajectory that maximizes energy transfer to the sensors in question,” Costantine explains. He says his team developed this system to control and recharge sensors used in agriculture, but that it could be extended to any situation where sensors are deployed in hard-to-reach areas.

How did the Bubonic Plague make the Italian Renaissance possible?

The Black Death (1347−1350) was a pandemic that devastated the populations of Europe and Asia. The plague was an unprecedented human tragedy in Italy. It not only shook Italian society but transformed it. The Black Death marked an end of an era in Italy, its impact was profound, and it resulted in wide-ranging social, economic, cultural and religious changes.[1] These changes, directly and indirectly, led to the emergence of the Renaissance, one of the greatest epochs for art, architecture, and literature in human history.

The Impact of the Plague of Italy

To Black Death spread to Italy from modern-day Russia. Genoese merchants spread the plague while fleeing a Mongol attack on their trading post in Crimea. The plague was carried and spread by the fleas that lived on the Black Rat and brought to Italy on the Genoese ships.[2] The population of Italy was ill prepared for the spread of the disease. There had been a series of famine and food shortages in the region, and the population was weak and vulnerable to disease, and furthermore, the population did not have any natural resistance to the disease. Italy was the most urbanized society in Europe, Milan, Rome, Florence, and other Italian centers among the largest on the continent.[3].

Building Blocks of the Genetic Code

Humans and all other living things have DNA, which contains hereditary information. The information in your DNA gives your cells instructions for producing proteins. Proteins drive important body functions, like digesting food, building cells, and moving your muscles.

Your DNA is the most unique and identifying factor about you—it helps determine what color your eyes are, how tall you are, and how likely you are to have certain health problems. Even so, over 99% of DNA sequences are the same among all people. It is the remaining 1% that explains much of what makes you, you!

DNA is arranged like two intertwined ropes, in a structure called a double helix (see figure 1). Each strand of DNA is made of four types of molecules, also called bases, attached to a sugar-phosphate backbone. The four bases are adenine (A), guanine (G), cytosine ©, and thymine (T). The bases pair in a specific way across the two strands of the helix: adenine pairs with thymine, and cytosine pairs with guanine.

Researchers reveal the mechanisms behind a natural bacteria killer

Scientists are one step closer to adapting the bacteria-killing power of a naturally occurring nanomachine, a tiny particle that performs a mechanical action.

In a study published in Nature, a UCLA-led team of researchers describe how the nanomachine recognizes and kills bacteria, and report that they have imaged it at atomic resolution. The scientists also engineered their own versions of the nanomachine, which enabled them to produce variations that behaved differently from the naturally occurring version.

Their efforts could eventually lead to the development of new types of antibiotics that are capable of homing in on specific species of microbes. Drugs tailored to kill only a certain species or strain of bacteria could offer numerous advantages over conventional antibiotics, including lowering the likelihood that bacteria will develop resistance. In addition, the tailored drugs could destroy harmful cells without wiping out beneficial bugs in the gut microbiome, and they could eventually offer the possibilities of being deployed to prevent bacterial infections, to kill pathogens in food and to engineer human microbiomes so that favorable bacteria thrive.