Scientists in the U.S. and U.K. have recently grown seven miniature human organs and housed them together on a chip to create a human-on-a-chip, a whole body biomimetic device. These clusters of assembled cells mimic how organs in the body function, both separately and in tandem.
The chip could take the place of animal and tissue testing for drugs in pharmaceutical development, say its creators. It will have to win regulatory approval in each country looking to use it for tests, and it could allow for insights into how organs interact, says Linda Griffith, professor of biological and mechanical engineering at the Massachusetts Institute of Technology.
Griffith heads The PhysioMimetics program at MIT, which has collaborated with CN Bio Innovations, a British company that creates live organ-on-a-chip devices. The $26.3-million development program is funded by the Defense Advanced Research Projects Agency.
A bioengineer and geneticist at Harvard’s Wyss Institute have successfully stored 5.5 petabits of data — around 700 terabytes — in a single gram of DNA, smashing the previous DNA data density record by a thousand times.
The work, carried out by George Church and Sri Kosuri, basically treats DNA as just another digital storage device. Instead of binary data being encoded as magnetic regions on a hard drive platter, strands of DNA that store 96 bits are synthesized, with each of the bases (TGAC) representing a binary value (T and G = 1 A and C = 0).
To read the data stored in DNA, you simply sequence it — just as if you were sequencing the human genome — and convert each of the TGAC bases back into binary. To aid with sequencing, each strand of DNA has a 19-bit address block at the start (the red bits in the image below) — so a whole vat of DNA can be sequenced out of order, and then sorted into usable data using the addresses.
The chips at the heart of our digital devices are manufactured by a few large companies, but an open-source approach to design could end their dominance — with implications for everyone.
Google runs a plethora of aspirational projects to explore one moonshot or another, but only some become real products. The company’s Project Loon internet balloons didn’t make the cut, having shut down in early 2021. However, one aspect of Loon has lived on to become its own Googley project. Google says it has used the Free Space Optical Communications (FSOC) links developed for Project Loon to beam hundreds of terabytes of data nearly five kilometers, no wires necessary.
Now under the purview of the company’s X labs, the little-known Project Taara is already enhancing connectivity in Kenya and India. Google says FSOC is essentially a fiber optic connection (up to 20 Gbps) without the wires, but it requires a direct line of sight. In Africa, Taara is now beaming data across the Congo River from Brazzaville in the Republic of Congo and Kinshasa in the Democratic Republic of Congo. After setting up the links over the past few years, Google is now sharing some of the project’s more impressive metrics.
Project Taara lead Baris Erkmen notes that Project Taara transmitted 700 TB over a recent 20-day period. This helped to back up wired connections in use by Google’s local partner Econet. Testing Taara in Africa makes sense because line-of-sight laser communication falls apart in a foggy locale like Google’s Bay Area home, and the fast-flowing Congo River has made connectivity in the region much more expensive.
The study of consciousness needs to be lifted out of the mysticism that has dominated it. Consciousness is not just a matter of philosophy or spirituality. It’s a matter of hard science. It’s a matter of understanding the brain and the mind — a pattern structure made out of information. It’s also a matter of engineering. If we can understand the functionality of the brain, its neural code, then we can build the same functionality into our computer systems. There’s no consensus on what produces consciousness, but everyone regardless of metaphysical views can agree what it is like to be conscious. Given that consciousness is subjectivity, what consciousness is like is what consciousness is.
‘Mind’ and ‘Consciousness’ are two different but somewhat overlapping terms related to the phenomenality of our experiential reality. Different species have a variety of their biological information processors which unsurprisingly results in qualia diversity. All species live in their own unique sensory universes. There is “something it is like to be” an organism. The human brain, our biological “wetware,” has a fractal structure on many genetic and abstract cognitive levels. Information is “modus operandi” of consciousness.
If we are to reason for the non-dual picture of the world then quantum physics is directly linked to consciousness. The human brain is a physical organ that transmits and interprets electrochemical signals. Its biochemistry is certainly governed by quantum physical laws, and consciousness — which is clearly related to the functioning of the brain — must therefore be related to the quantum physical processes going on within the brain and in the cosmos at large. Research has shown that consciousness is non-local, a scientific way of alluding to a connection within a higher dimensional order. Matter has also been shown to be non-local, which hints that matter might be an expression of consciousness, emerging from the ‘Unified Field’ — the quantum layer of pure potentiality — the code layer beneath all dimensions where time and space are information.
Reality is fundamentally experiential. Nothing is real for us until perceived. A little while ago, the idea that our minds create reality would have seemed preposterous to most westerners. But today everyone in the West becomes a bit more susceptible to this bold new idealistic, computationalist thinking along with certain QM interpretations directly pointing to the fundamental laws of Nature emerging from consciousness…
[Matt] from [DIY Perks] has made a name for himself building nice custom computing machines, and his latest triple-monitor luggable PC (video after the break) is sure to give most high-performance desktop machines a run for their money.
The large central monitor folding laptop monitors mounted vertically on either size look impressive, but only just scratches the surface of this build. Hidden behind aluminum panels are Ryzen 5950X CPU and RTX 3,080 GPU with water cooling, 64 GB of RAM, and two 8 TB SSDs. A set of high-quality speaker drivers, subwoofer, and audio amps is also included. All this hardware pulls about 600 W of power from a large DC-DC converter block, which in turn receives power from either a pair of onboard AC-DC converters or a 16 V – 63 V DC source, like a battery system.
To mount everything to the back of the main monitor, [Matt] created 3D printed adaptor blocks with threaded inserts which slide under existing hooks on the back of the monitor. Aluminum angles screw to these blocks to cover the edges of the display panel, together with a large mounting plate with pre-drilled holes to mount all the components on standoffs. A set of adjustable and removable legs mount to the side of the PC. A hinged door in the back cover allows storage space for a keyboard and mouse during transport. When folded, the laptop monitors don’t fully cover the main monitor, so [Matt] created a leather cover that doubles as a cable and accessory organizer.
According to researchers from the Singapore University of Technology and Design (SUTD), a recently discovered family of two-dimensional (2D) semiconductors could pave the way for high-performance and energy-efficient electronics. Their findings, published in npj 2D Materials and Applications, may lead to the fabrication of semiconductor devices applicable in mainstream electronics and optoelectronics—and even potentially replace silicon-based device technology altogether.
In the quest of miniaturizing electronic devices, one well-known trend is Moore’s law, which describes how the number of components in the integrated circuits of computers doubles every two years. This trend is possible thanks to the ever-decreasing size of transistors, some of which are so small that millions of them can be crammed onto a chip the size of a fingernail. But as this trend continues, engineers are starting to grapple with the inherent material limitations of silicon-based device technology.
“Due to the quantum tunneling effect, shrinking a silicon-based transistor too small will lead to highly uncontrollable device behaviors,” said SUTD Assistant Professor Ang Yee Sin, who led the study. “People are now looking for new materials beyond the ‘silicon era’, and 2D semiconductors are a promising candidate.”
