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Category: biotech/medical – Page 820

Blood Test Uses Fragmentomics to Detect Liver Cancer

Another advantage of fragmentomics is that it requires much less blood than other liquid biopsy tests, she added.

The fragmentomics approach is also appealing because it requires only a blood draw, Dr. Greten noted, which is typically faster, easier to get, and less expensive than an ultrasound.

Fragmentomics is a next-generation liquid biopsy approach, said Dr. Velculescu. And it can potentially be used to detect other kinds of cancer, in addition to those the team has already studied, he added.

Cancer Treating Nano-Drones

This post is also available in: he עברית (Hebrew)

A research team from UNIST has made a discovery that might revolutionize cancer treatment as we know it-new cell-engaging nano-drones that were designed to target and eliminate cancer cells selectively.

These tiny bots are called NK cell-engaging nano-drones (NKeNDs), and their success lies in their ability to engage natural killer (NK) cells, the body’s frontline defenders against cancer. Using NK cells in cancer treatment is not new, but what sets these nanodrones apart is their precision. They are engineered to zero in on cancer cells almost like guided missiles.

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

🧬 💉 🔬 https://www.news-medical.net/news/20240103/EZH2-inhibitors-s…tment.aspx Type1Diabetes # EZH2Inhibitors # BetaCellRegener…

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

AI aids colonoscopy by acting as ‘extra pair of eyes’, spotting tumors

He further mentioned that the AI tool functioned like an “extra pair of eyes,” identifying potential tumors within the video footage.

In short, the AI tool assists junior doctors during colonoscopies by analyzing video footage from the endoscope and identifying potential tumors. It aids in detecting adenomas, particularly those smaller than five millimeters (mm) in diameter.

Scientists fuse brain-like tissue with electronics to make computer

Scientists have fused brain-like tissue with electronics to make an ‘organoid neural network’ that can recognise voices and solve a complex mathematical problem. Their invention extends neuromorphic computing – the practice of modelling computers after the human brain – to a new level by directly including brain tissue in a computer.

The system was developed by a team of researchers from Indiana University, Bloomington; the University of Cincinnati and Cincinnati Children’s Hospital Medical Centre, Cincinnati; and the University of Florida, Gainesville. Their findings were published on December 11.

Research Alert: More Colorectal and Endometrial Cancers Could Be Treated with Immunotherapy, Study Shows

In a new study published in Cancer Cell, YSM researchers at Yale Cancer Center find immunotherapy could benefit thousands of additional patients with colorectal and endometrial cancers who are not currently being offered it:

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it. Researchers showed the importance of looking at DNA Mismatch Repair Deficiency (MMR-D) as a guiding marker for treatment decisions using immune checkpoint inhibitors (ICIs). MMR-D is associated with an increased risk of developing several types of cancer and is the most common cause of hereditary endometrial cancer.

The study, which published in Cancer Cell on December 28, compared two lab testing methods to diagnose cancers— traditional immunohistochemistry (IHC) (a lab technique that uses antibodies to detect antigens in tissues) — and next-generation sequencing (NGS) — a new technology used for DNA sequencing that can detect specific patterns of mutations. The researchers discovered that NGS offers a more accurate assessment of MMR status.

Voyager Therapeutics, Novartis Enter Strategic Capsid Collaboration

Voyager Therapeutics entered a strategic collaboration and capsid license agreement with Novartis to advance potential gene therapies for Huntington’s disease and spinal muscular atrophy, providing Novartis a target-exclusive license to access its TRACER capsids and other intellectual property.

Novartis obtains target-exclusive access to Voyager’s TRACER capsids related to Huntington’s disease and spinal muscular atrophy.

World’s first partial heart transplant proves successful in first year

The world’s first partial heart transplant has achieved what researchers have spent more than a year hoping for—functioning valves and arteries that grow along with the young patient, as hypothesized by the pioneering team behind the procedure at Duke Health.

The procedure was performed in the spring of 2022, in an infant who needed . The previous standard of care—using valves that were non-living—would not grow along with the child, requiring frequent replacement, entailing surgical procedures that carry a 50% mortality rate.

A study led by Duke Health physicians, appearing online Jan. 2 in the Journal of the American Medical Association (JAMA), found that the new manner of procurement used during the partial transplant led to two well-functioning valves and arteries that are growing in concert with the child as if they were native vessels.

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