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With the help of NASA and Japan, Uganda has officially become a spacefaring nation — and its newly-launched PearlAfricaSat-1 craft has some pretty nifty tech onboard.

As the Uganda-based Nile Post reports, the satellite launched out of NASA’s Mid-Atlantic Regional Spaceport facility in Virginia on the morning of November 7 will not only provide important agricultural and security monitoring features for the developing nation, but will also conduct experiments involving the 3D printing of human tissue.

Per the Ugandan news site, the tissues printed on PearlAfricaSat-1 will be used in research into the effects microgravity has on ovary function — and as Quartz notes in its write-up of the NASA and Japan-supported mission, the microgravity aspect of the experiments is key because “bioprinting” human organs is difficult to achieve with Earth’s gravity.

Researchers revealed why cancer cells require proteins that fix copper ions in order to develop and spread throughout the human body. Possible novel treatment targets have been discovered as a result of recent research on the connections between proteins and how they bind to metals in cancer-related proteins.

Small amounts of the metal copper are required by human cells to perform essential biological functions. The conclusion drawn from studies demonstrating higher copper levels in tumor cells and blood serum from cancer patients is that cancer cells require more copper than healthy cells. Additionally, more copper-binding proteins are active when copper levels are higher. “Therefore, these proteins are highly important to study when it comes to understanding the development of cancer and deeper knowledge about them can lead to new targets for treatment of the disease,” said Pernilla Wittung-Stafshede, Professor of Chemical Biology at Chalmers University of Technology, Sweden.

Most cancer-related deaths are due to the fact that metastases — secondary tumors — form in several places in the body, for example, in the liver or lungs. A protein called Memo1 is part of the signaling systems that cancer cells use to grow and spread around the body. Previous research has shown that when the gene for Memo1 is inactivated in breast cancer cells, their ability to form metastases decreases. A research group from Chalmers wanted to take a closer look at the connection between Memo1 and copper. In a new study published in the scientific journal PNAS, the researchers examined the Memo1 protein’s ability to bind copper ions through a series of test tube experiments. They discovered that the protein binds copper, but only the reduced form of copper. It is this form of copper ions that is most common in living cells. It’s an important discovery because reduced copper, while it is needed in the body, also contributes to redox-reactions that damage — or even kill — the cells.

University of Missouri researchers made the discovery while using bioluminescent imaging technology to study how nicotinamide riboside supplements work inside the body.

Commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, were linked to benefits related to cardiovascular, metabolic, and neurological health in previous studies. However, new research from the University of Missouri (MU) has found NR could actually increase the risk of serious disease, including developing cancer.

Supplements containing nicotinamide riboside are often marketed as NAD+ boosters claimed benefits including increased energy, anti-aging/longevity/healthy aging, improved cellular energy metabolism and repair, increased vitality, and improved heart health.

𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐢𝐝𝐞𝐧𝐭𝐢𝐟𝐲 𝐧𝐞𝐮𝐫𝐨𝐧𝐬 𝐭𝐡𝐚𝐭 𝐫𝐞𝐬𝐭𝐨𝐫𝐞 𝐰𝐚𝐥𝐤𝐢𝐧𝐠 𝐚𝐟𝐭𝐞𝐫 𝐩𝐚𝐫𝐚𝐥𝐲𝐬𝐢𝐬

𝙄𝙣 𝙖 𝙢𝙪𝙡𝙩𝙞-𝙮𝙚𝙖𝙧 𝙧𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙥𝙧𝙤𝙜𝙧𝙖𝙢 𝙘𝙤𝙤𝙧𝙙𝙞𝙣𝙖𝙩𝙚𝙙 𝙗𝙮 𝙩𝙝𝙚 𝙩𝙬𝙤 𝙙𝙞𝙧𝙚𝙘𝙩𝙤𝙧𝙨 𝙤𝙛.𝙉𝙚𝙪𝙧𝙤𝙍𝙚𝙨𝙩𝙤𝙧𝙚—𝙂𝙧𝙚́𝙜𝙤𝙞𝙧𝙚 𝘾𝙤𝙪𝙧𝙩𝙞𝙣𝙚, 𝙖 𝙣𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙘𝙚 𝙥𝙧𝙤𝙛𝙚𝙨𝙨𝙤𝙧 𝙖𝙩 𝙀𝙋𝙁𝙇, 𝙖𝙣𝙙 𝙅𝙤𝙘𝙚𝙡𝙮𝙣𝙚 𝘽𝙡𝙤𝙘𝙝, 𝙖 𝙣𝙚𝙪𝙧𝙤𝙨𝙪𝙧𝙜𝙚𝙤𝙣 𝙖𝙩 𝙇𝙖𝙪𝙨𝙖𝙣𝙣𝙚 𝙐𝙣𝙞𝙫𝙚𝙧𝙨𝙞𝙩𝙮 𝙃𝙤𝙨𝙥𝙞𝙩𝙖𝙡 (𝘾𝙃𝙐𝙑)—𝙥𝙖𝙩𝙞𝙚𝙣𝙩𝙨 𝙬𝙝𝙤 𝙝𝙖𝙙 𝙗𝙚𝙚𝙣 𝙥𝙖𝙧𝙖𝙡𝙮𝙯𝙚𝙙 𝙗𝙮 𝙖 𝙨𝙥𝙞𝙣𝙖𝙡 𝙘𝙤𝙧𝙙 𝙞𝙣𝙟𝙪𝙧𝙮 𝙖𝙣𝙙 𝙬𝙝𝙤 𝙪𝙣𝙙𝙚𝙧𝙬𝙚𝙣𝙩 𝙩𝙖𝙧𝙜𝙚𝙩𝙚𝙙 𝙚𝙥𝙞𝙙𝙪𝙧𝙖𝙡 𝙚𝙡𝙚𝙘𝙩𝙧𝙞𝙘𝙖𝙡 𝙨𝙩𝙞𝙢𝙪𝙡𝙖𝙩𝙞𝙤𝙣 𝙤𝙛 𝙩𝙝𝙚 𝙖𝙧𝙚𝙖 𝙩𝙝𝙖𝙩 𝙘𝙤𝙣𝙩𝙧𝙤𝙡𝙨 𝙡𝙚𝙜 𝙢𝙤𝙫𝙚𝙢𝙚𝙣𝙩 𝙬𝙚𝙧𝙚 𝙖𝙗𝙡𝙚 𝙩𝙤 𝙧𝙚𝙜𝙖𝙞𝙣 𝙨𝙤𝙢𝙚 𝙢𝙤𝙩𝙤𝙧 𝙛𝙪𝙣𝙘𝙩𝙞𝙤𝙣.

Continue reading “Scientists identify neurons that restore walking after paralysis” »

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Continue reading “Longitudinal Biomarker Optimization: A Road To Maximize Health And Longevity?” »

Ever wonder why some 90-year olds don’t seem to slow down and seem. to retain the mental and physical capacity of someone half their age?
Do they have good genes? Or is there a way that all of us can get older without getting old?

That’s what Dr. Nir Barzilai, founder of the Institute for Aging Research at the Albert Einstein College of Medicine, set out to answer in his book, Age Later.

Continue reading “A discussion with Dr. Nir Barzaili on Age Later” »

T ransplant medicine could take a giant leap forward if donor organs could soak up oxygen for longer and decay delayed. A technology called OrganEx, described in Nature from a team at Yale, promises to do just that. The researchers stopped the hearts of pigs and an hour later used OrganEx, then cataloged the return of bodily functions. The new approach far exceeded the ability of existing technology to prolong organ viability.

Pigs have long been a popular animal model of human disease because they are about our size and their hearts and blood vessels are quite similar. They have also had fictional roles in medicine.

In the Twilight Zone episode Eye of the Beholder, Janet Tyler has undergone multiple procedures to replace the “pitiful twisted lump of flesh” that is her face with something more acceptable. At the end, as the bandages are slowly unrolled from yet another failed procedure, we see that she naturally looks like us, considered hideous in her world where most people, including the nurse and doctor, have pig faces. Janet and others like her are sent to live among themselves.

Scientists have managed to do what many might have thought impossible. According to new research published in the journal Nature, a group of researchers from the Swiss research group NeuroRestore was able to identify neurons that could restore the ability to walk in paralyzed individuals. The researchers published their findings back in September.

The micro-robots consist of a special kind of bacteria.

Scientists have conceived of a new way to deliver cancer-killing compounds, called enterotoxins, to tumors using bionic bacteria that are steered by a magnetic field, according to a report by Inverse.

“Cancer is such a complex disease, it’s hard to combat it with one weapon,” said Simone Schürle-Finke, a micro-roboticist at the Swiss Federal Institute of Technology in Zürich, Switzerland, and one of the authors of the new study.

Continue reading “Scientists use magnets to deliver cancer-killing ‘micro-robots’ into the body” »