AI has officially entered the field of biology. Meet Evo, a GPT fed millions of microbes instead of words. Read all about it.
Evo marks the next frontier in machine learning by interpreting biological sequence data, including DNA, RNA, and proteins.
Category: biotech/medical – Page 768
The future of ultrafast electronics
Physicist Matthias Kling studies photons and the things science can do with ultrafast pulses of X-rays. These pulses last just attoseconds – a billionth of a billionth of a second, Kling says. He uses them to create slo-mo “movies” of electrons moving through materials like those used in batteries and solar cells. The gained knowledge could reshape fields like materials science, ultrafast and quantum computers, AI, and medical diagnostics, Kling tells host Russ Altman on this episode of Stanford Engineering’s The Future of Everything podcast.
Experimental therapeutic reduces advanced-stage influenza viral loads faster than current therapies in preclinical study
Eradivir, a preclinical biotech company, has developed a patent-pending antiviral therapeutic that reduces lung viral loads of advanced-stage influenza in preclinical studies quicker and more effectively than currently available therapies.
A single intranasal dose of EV25, a bispecific small molecule developed by Eradivir, acts faster than the current standard of care, eliminating the detectable virus within 24 hours. EV25 also has a window of efficacy of 96 hours postinfection, which is broader than the current standard of care.
A research paper titled “Targeted recruitment of immune effector cells for rapid eradication of influenza virus infections” has been published in Proceedings of the National Academy of Sciences.
Live Longer, Look Younger: The Groundbreaking Science Of IL-11 Inhibition, 3 Molecules To Reduce It!
Unlock the Secret to a Longer, Healthier Life: The Power of Inhibiting IL-11
Discover the groundbreaking science behind aging in this video, Mr. Bill Faloon presents:
• The Role of IL-11 in Aging: Learn how this inflammatory cytokine accelerates aging and contributes to age-related diseases.
• The Benefits of Inhibiting IL-11: Discover how reducing IL-11 levels can lead to increased lifespan, improved health, and a more youthful appearance.
• Natural Ways to Inhibit IL-11: Learn about dietary supplements and lifestyle habits that can help you lower IL-11 levels.
• The Future of Anti-Aging Medicine: Explore the latest research on drugs and therapies targeting IL-11 and how they may revolutionize the way we approach aging.
https://www.nature.com/articles/s41586-024-07701-9
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386112/
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754292/
Understanding interleukin 11 as a disease gene and therapeutic target.
Blocking Inflammation Protein Extends Lifespan.
https://www.telegraph.co.uk/news/2024/07/17/scientists-find-…op-cancer/
Advances in Y chromosome analysis aid in horse breeding and conservation
Researchers at the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) are helping uncover new information about the Y chromosome in horses, which will help owners identify optimal lineages for breeding and help conservationists preserve breed diversity.
“Because of its complex structure, the Y chromosome is much harder to sequence, making our knowledge of it far from complete,” said Dr. Gus Cothran, a professor emeritus in the VMBS’ Department of Veterinary Integrative Biosciences (VIBS). “In fact, scientists used to believe that the Y chromosome lacked genetic variety, which we believed meant that it didn’t contribute much to species diversity.”
However, Cothran’s new research collaboration, led by the University of Veterinary Medicine Vienna, has uncovered that the Y chromosome does have meaningful variation and is important for species diversity.
Here’s how your cholesterol level shapes your dementia risk
Scientists have discovered your cholesterol levels could be significantly linked to your risk of developing dementia. And it’s not just high cholesterol that matters: fluctuating levels over several years could increase your chances of the disease by 60 per cent, suggests a new study of 10,000 people.
The research also suggests that, even if you don’t develop dementia, a large cholesterol variability – swinging from high to low levels – is linked to an increased risk of general cognitive decline by 23 per cent.
Ancient Gene Reprograms Stem Cells to Create a Living Mouse
Summary: Scientists have reprogrammed mouse cells into pluripotent stem cells using a gene from choanoflagellates, single-celled organisms related to animals. This breakthrough demonstrates that key genes driving stem cell formation existed in unicellular ancestors nearly a billion years ago.
The resulting stem cells were used to create a chimeric mouse, showcasing how ancient genetic tools can integrate with modern mammalian biology. This discovery redefines the evolutionary origins of stem cells and may inform regenerative medicine advancements.