Lifeboat Foundation

You may already know that it’s important to wash your hands, wear a face mask and avoid sick people while neutropenic.

But is there anything else you should — or should not — be doing to avoid infections when you’re immunocompromised by a low white blood cell count during or after cancer treatment?

We spoke with internal medicine expert Carmen Escalante, M.D., for insight. Here are five precautions she shares with immunocompromised patients and their caregivers.

A Florida woman is suing an eye drop manufacture claiming that its product — which has been linked to a deadly bacteria outbreak — made her legally blind.

Sixty-eight-year-old Clara Elvira Oliva is taking legal action against Global Pharma Healthcare after suffering such a severe infection from using its EzriCare Artificial Tears that she had to have her eye removed, according to court documents.

Oliva’s right eye was removed and replaced with a plastic implant in September 2022 to control a “severe antibiotic resistant infection,” according to the lawsuit filed earlier this month in Federal court in Miami, Florida.

The eye drops were contaminated with an antibiotic-resistant form of Pseudomonas aeruginosa, an aggressive bacterium, according to the CDC.

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Your circadian rhythm doesn’t just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review paper published in the journal Trends in Cell Biology, researchers discuss the role of circadian rhythms in tumor progression and spread and describe how we could better time when patients are tested for cancer and when they receive therapies to improve diagnostic accuracy and improve treatment success.

“The circadian rhythm governs most of the cellular functions implicated in cancer progression, and therefore its exploitation opens new promising directions in the fight against metastasis,” write the authors, molecular oncologists Zoi Diamantopoulou, Ana Gvozdenovic, and Nicola Aceto from the ETH Zurich in Switzerland.

Our circadian rhythms help our bodies synchronize different tasks throughout the day, including gene expression, immune function, and cell repair. We’ve long known that chronically disrupted circadian rhythms—as a result of erratic sleep patterns, jet lag, or shift work, for example—can predispose us to a number of health issues, including cancer. More recent work has shown that circadian rhythms are not only involved in tumor onset, but also govern cancer progression and metastasis, the colonization of secondary sites within the body.

It’s pretty well known that usually two sexes have to be involved for reproduction, but a team of scientists in Japan might have just blown that assumption out of the water. Led by Katsuhiko Hayashi, a professor of genome biology at Osaka University in Japan, the team have been able to create mice with parents who are both biologically male.

• Restores overall digestive health

• Improves glucose metabolism by reducing levels of blood glucose.

Continue reading “Sugar Shift® + Metabolism Support Probiotics + BiotiQuest®” »

Doctors are assuring the public that it’s not going to take over the world and kill us all, but it is something we need to be aware of.

The researchers add that these data demonstrate that CRISPRa is generally applicable across chromatin states and cell types, and highlights the factors that impact the degree of gene activation and how easy it is to reproduce the effects. Understanding these factors is important in the design and analysis of CRISPRa screens, which are used to look for genes involved in genetic diseases, the team points out.

Further study is required to continue to add to these rules and to see whether different CRISPRa or CRISPR interference techniques behave in a similar way.

“Our research has established a system for reporting the effectiveness of CRISPR activation in stem cells, allowing us to gain a better understanding of how CRISPRa works in multiple cell states,” says Qianxin Wu, PhD, first author from Wellcome Sanger. “We also showed that CRISPR gene activation is powerful enough to induce stem cells to differentiate into other cell states. This suggests that CRISPRa screens can be used to search for genes involved in cellular processes or to generate more accurate models of cell types in the body, aiding research into genetic diseases and regenerative medicine.”