Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 509

New rapid blood test can detect stroke in 6 hours, save lives

Blood test detects stroke quickly:

The Testing for Identification of Markers of Stroke trial shows the accuracy of a new blood test for identifying stroke.

A team of scientists has developed a new test by combining blood-based biomarkers with a clinical score. The main goal was to identify patients experiencing large vessel occlusion (LVO) stroke.

LVO strokes, a severe form of stroke, are often characterized by a sudden onset of symptoms and significant neurological damage. They occur when an artery in the brain is blocked, depriving the brain of essential oxygen.

Introducing the Frontier Safety Framework

Our approach to analyzing and mitigating future risks posed by advanced AI models.

Google DeepMind has consistently pushed the boundaries of AI, developing models that have transformed our understanding of what’s possible. We believe that AI technology on the horizon will provide society with invaluable tools to help tackle critical global challenges, such as climate change, drug discovery, and economic productivity. At the same time, we recognize that as we continue to advance the frontier of AI capabilities, these breakthroughs may eventually come with new risks beyond those posed by present-day models.

Today, we are introducing our Frontier Safety Framework — a set of protocols for proactively identifying future AI capabilities that could cause severe harm and putting in place mechanisms to detect and mitigate them. Our Framework focuses on severe risks resulting from powerful capabilities at the model level, such as exceptional agency or sophisticated cyber capabilities. It is designed to complement our alignment research, which trains models to act in accordance with human values and societal goals, and Google’s existing suite of AI responsibility and safety practices.

Scientists develop a soft robot that mimics a spider’s leg

In organisms, fluid is what binds the organs, the and the musculoskeletal system as a whole. For example, hemolymph, a blood-like fluid in a spider’s body, enables muscle activation and exoskeleton flexibility. It was the cucumber spider inhabiting Estonia that inspired scientists to create a complex , where soft and rigid parts are made to work together and are connected by a liquid.

According to Indrek Must, Associate Professor of Soft Robotics, the designed soft robot is based on real reason. “Broadly speaking, our goal is to build systems from both natural and artificial materials that are as effective as in wildlife. The robotic leg could touch delicate objects and move in the same complex environments as a living spider,” he explains.

In a published in the journal Advanced Functional Materials, the researchers show how a robotic foot touches a primrose stamen, web, and pollen grain. This demonstrates the soft robot’s ability to interact with very small and delicate structures without damaging them.

Watch: Sony’s new microsurgery robot stitches up a corn kernel

Sony has shown off its new surgical robot doing some super-precise work sewing up a tiny slit in a corn kernel. It’s the first machine of its kind that auto-switches between its different tools, and has successfully been tested in animal surgery.

It’s designed to help in the field of super-microsurgery, a highly specialized field in which surgeons operate on extremely small blood vessels and nerves, with diameters well under 1 mm (0.04 in). As you might imagine, this kind of thing requires incredibly steady hands, and specialists in this field often do their work whole looking through a microscope.

Thus, it’s an ideal place for some robotic assistance, and there are a number of surgical robots already in clinical use from companies like Intuitive Surgical, Stryker and others. We’re not talking fully autonomous AI-powered robot surgeons here, we’re talking teleoperation tools that allow surgeons to magnify their vision while shrinking their hand motions.

Some brain injury patients would recover if life support weren’t ended

A substantial proportion of people with a traumatic brain injury who had their life support withdrawn may have survived and at least partially recovered, a study suggests.

Traumatic brain injuries can occur due to a forceful blow, a jolt to the head or an object entering the brain, such as a bullet…

After comparing people with brain injuries whose life support was continued with those who had it turned off, scientists calculated that around 40 per cent in the latter group may have made some recovery.

By Moheb Costandi

Gene Editing Breakthrough: CRISPR Improves Vision in Clinical Trial

Jason Comander, MD, PhD, performs the procedure to deliver the CRISPR-based medicine as part of the BRILLIANCE trial in September 2020 at Mass Eye and Ear. Credit: Mass Eye and Ear.

All 14 trial participants, including 12 adults (ages 17 to 63) and two children (ages 10 and 14), were born with a form of Leber Congenital Amaurosis (LCA) caused by mutations in the centrosomal protein 290 (CEP290) gene. They underwent a single injection of a CRISPR/Cas9 genome editing medicine, EDIT-101 in one eye via a specialized surgical procedure. This trial, which included the first patient to ever receive a CRISPR-based investigational medicine directly inside the body, focused primarily on safety with a secondary analysis for efficacy.

No serious treatment or procedure-related adverse events were reported, nor were there any dose-limiting toxicities. For efficacy, the researchers looked at four measures: best-corrected visual acuity (BCVA); dark-adapted full-field stimulus testing (FST), visual function navigation (VNC, as measured by a maze participants completed), and vision-related quality of life.

AI Uncovers Hidden Differences in Male and Female Brain Structures

Summary: Researchers use AI to reveal distinct cellular-level differences in the brains of men and women, focusing on white matter. These findings show AI can accurately identify sex-based brain patterns invisible to human eyes.

The study suggests that understanding these differences can enhance diagnostic tools and treatments for brain disorders. This research emphasizes the need for diversity in brain studies to ensure comprehensive insights into neurological diseases.

Immunotherapy may boost survival after lung cancer surgery

Immunotherapy can boost the survival of early-stage lung cancer patients eligible for surgery when it’s combined with chemotherapy, a new clinical trial reports.

Those who got immunotherapy before and after surgery — along with pre-surgical chemo — had a 42% lower risk of cancer progression, recurrence or death than those who only received chemo, according to findings published Wednesday in the New England Journal of Medicine.

Further, about 25% of those who got immunotherapy and chemo had no cancer at all remaining after their surgery, compared with about 5% of those who got chemo alone.