Researchers are devising a blood test screening for 11 newly discovered biomarkers of dementia. They say the test could predict its development 15 years before symptom onset.
Category: biotech/medical – Page 454
Scientists have welcomed a “truly wonderful” new drug for a hard-to-treat and aggressive form of cancer.
Researchers led by a team at Queen Mary University of London said their new treatment “quadrupled” three-year survival rates and increased average survival by 1.6 months.
Academics said that the new drug, which works by cutting off the tumour ’s food supply, is the first of its type for mesothelioma in 20 years.
https://music.youtube.com/watch?v=n_LefGJgOJ8&si=UoInnL8Xy_wsXv_
Currently listening to this. He’s pretty decent, up there with Dr Daniel Amen in advancement/ideas. I barely started this episode but it seems AI can help in medicine and there’s more in this podcast concerning our personal health. This is some key issues for longevity.
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View the Show Notes For This Episode: https://bit.ly/ep-855
Dr. Eric Topol is the Founder and Director of the Scripps Research Translational Institute, Professor of Molecular Medicine, and Executive Vice-President of Scripps Research. He has published over 1,200 peer-reviewed articles with more than 330,000 citations, was elected to the National Academy of Medicine, and is one of the top 10 most cited researchers in medicine. His principal scientific focus has been on individualized medicine using genomic, digital, and AI tools.
This episode is brought to you by Rupa Health, Pendulum, Thrive Market, and Fatty15.
Studies show that physical activity is actually a mental health exercise. One article that states just 15 minutes of walking, especially in the out-of-doors, can boost mood and reduce feelings of depression.
People seem to think more clearly after a brisk walk as well. It makes sense. As the heart pumps oxygen and nutrients to working muscles, the brain gets the same benefits.
Are there foods that might help our brains stay focused? In 2015, scientists reported on a diet that was found to help slow the gradual decline in cognitive function we may experience as we age. It was a hybrid of the Mediterranean diet and the DASH diet (Dietary Approaches to Stop Hypertension) cutely named the MIND diet (Mediterranean-DASH Diet Intervention for Neurodegenerative Delay).
This isn’t rocket science it’s neuroscience.
Ever since the dawn of antiquity, people have strived to improve their cognitive abilities. From the advent of the wheel to the development of artificial intelligence, technology has had a profound leverage on civilization. Cognitive enhancement or augmentation of brain functions has become a trending topic both in academic and public debates in improving physical and mental abilities. The last years have seen a plethora of suggestions for boosting cognitive functions and biochemical, physical, and behavioral strategies are being explored in the field of cognitive enhancement. Despite expansion of behavioral and biochemical approaches, various physical strategies are known to boost mental abilities in diseased and healthy individuals. Clinical applications of neuroscience technologies offer alternatives to pharmaceutical approaches and devices for diseases that have been fatal, so far. Importantly, the distinctive aspect of these technologies, which shapes their existing and anticipated participation in brain augmentations, is used to compare and contrast them. As a preview of the next two decades of progress in brain augmentation, this article presents a plausible estimation of the many neuroscience technologies, their virtues, demerits, and applications. The review also focuses on the ethical implications and challenges linked to modern neuroscientific technology. There are times when it looks as if ethics discussions are more concerned with the hypothetical than with the factual. We conclude by providing recommendations for potential future studies and development areas, taking into account future advancements in neuroscience innovation for brain enhancement, analyzing historical patterns, considering neuroethics and looking at other related forecasts.
Keywords: brain 2025, brain machine interface, deep brain stimulation, ethics, non-invasive and invasive brain stimulation.
Humans have striven to increase their mental capacities since ancient times. From symbolic language, writing and the printing press to mathematics, calculators and computers, mankind has devised and employed tools to record, store, and exchange thoughts and to enhance cognition. Revolutionary changes are occurring in the health care delivery system as a result of the accelerating speed of innovation and increased employment of technology to suit society’s evolving health care needs (Sullivan and Hagen, 2002). The aim of researchers working on cognitive enhancement is to understand the neurobiological and psychological mechanisms underlying cognitive capacities while theorists are rather interested in their social and ethical implications (Dresler et al., 2019; Oxley et al., 2021).
The authors of a recent review published in Ageing Research Reviews summarize the research on epigenetic reprogramming and its potential as a rejuvenation therapy [1].
Aging leads to changes in the epigenome. Those changes can lead to alterations in gene regulation, affecting cellular homeostasis, and can play a role in age-associated phenotypes. Epigenetic modifications, the addition or removal of chemical groups to the DNA or DNA-associated proteins, have a profound impact on gene expression, tissue functions, and identity [2].
This review’s authors believe epigenetic reprogramming to be among the most currently promising interventions to stop or delay aging, potentially even reversing it at the cellular level. They believe that epigenetics are the basis of aging; therefore, being able to impact the epigenome would allow them to address multiple Hallmarks of Aging simultaneously.
Semiconductor devices are small components that manage the movement of electrons in contemporary electronic gadgets. They are essential for powering a wide range of high-tech products, including cell phones, laptops, and vehicle sensors, as well as cutting-edge medical devices. However, the presence of material impurities or variations in temperature can interfere with electron flow, causing instability.
But now, theoretical and experimental physicists from the Würzburg-Dresden Cluster of Excellence ct.qmat—Complexity and Topology in Quantum Matter have developed a semiconductor device from aluminum-gallium-arsenide (AlGaAs). This device’s electron flow, usually susceptible to interference, is safeguarded by a topological quantum phenomenon. This groundbreaking research was recently detailed in the esteemed journal Nature Physics.
“Thanks to the topological skin effect, all of the currents between the different contacts on the quantum semiconductor are unaffected by impurities or other external perturbations. This makes topological devices increasingly appealing for the semiconductor industry. They eliminate the need for the extremely high levels of material purity that currently drive up the costs of electronics manufacturing,” explains Professor Jeroen van den Brink, director of the Institute for Theoretical Solid State Physics at the Leibniz Institute for Solid State and Materials Research in Dresden (IFW) and a principal investigator of ct.qmat.
Human telomerase threatens genome integrity by adding telomeres to broken chromosomes and is held in check by ATR kinase signaling.
A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests. The study is published in the journal Nature Nanotechnology.
Carefully controlled inhalation of a specific type of graphene—the world’s thinnest, super strong and super flexible material —has no short-term adverse effects on lung or cardiovascular function, the study shows. The first controlled exposure clinical trial in people was carried out using thin, ultra-pure graphene oxide—a water-compatible form of the material.
Researchers say further work is needed to find out whether higher doses of this graphene oxide material or other forms of graphene would have a different effect. The team is also keen to establish whether longer exposure to the material, which is thousands of times thinner than a human hair, would carry additional health risks.
A tiny robot with a clutch that mimics similar mechanisms found in microorganisms could be used to trigger the internal workings of a cell.
By Alex Wilkins