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Archive for the ‘biotech/medical’ category: Page 4

Apr 11, 2024

Scientists share warning after bird flu found in some New York City birds

Posted by in category: biotech/medical

“People don’t believe there’s wildlife here, but we’re really very, very rich in wildlife because we’re on the Atlantic Flyway and we have so many places for the birds to stop over during migration,” McMahon said.

Researchers and local students spent nearly two years collecting samples from a wide range of birds, including ones we see often like ducks and geese, to raptors.

Their findings were published earlier this month.

Apr 11, 2024

Just 1 Dose of New Antibiotic Class Eliminates Resistant Blood Infections in Mice

Posted by in category: biotech/medical

Scientists have figured out a whole new way to cut the legs out from underneath drug-resistant bacterial infections.

The new class of antibiotic was identified by researchers at Uppsala University in Sweden, and while it has only been tested on mice, the team hopes that further development of the drug can “make an important contribution to the ongoing struggle against antibiotic resistance.”

The unique medicine, like many other antibiotics currently in development, targets the double membrane that surrounds gram-negative bacteria, like Escherichia coli, which can cause bowel and blood infections, and Klebsiella pneumoniae, which can cause lung, bladder, and blood infections.

Apr 11, 2024

Scientists reconstruct assembly of the human centriole, image by image, for the first time

Posted by in category: biotech/medical

Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as “organelles.” Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

Apr 11, 2024

Artificial ovary? First atlas of human ovary, a fertility breakthrough

Posted by in categories: biotech/medical, innovation

Researchers have created an “atlas” of the human ovary, which could lead to the development of artificial ovaries and restore fertility in patients.

Apr 11, 2024

Depleting Stem Cells Improves Immunity

Posted by in category: biotech/medical

Aging is a life process where the body slowly breaks down and becomes more vulnerable to external stimuli. For example, bones in older individuals become frail and muscle deteriorates. Additionally, older individuals are more susceptible to disease with a compromised immune system. In many cases there are protocols and guidelines in place to protect those with high susceptibility to disease. During the COVID-19 pandemic older patients had to be extremely careful to avoid contracting COVID-19.

Unfortunately, aging is a natural part of life. However, scientists are working to make the process of aging a little easier. Due to the increased average lifespan, aging has been a progressively growing field. Physicians and scientists are working to understand how we age and if there are secrets to be uncovered that would help avoid, prevent, or cure age-related diseases, such as cancer.

Stem cells are self-renewing cells in the body with the ability to differentiate into any cell type. The outcome to which final cell type it turns into is dependent on what the body needs. Regarding the immune system, the body generates more myeloid immune cells. Aging of the immune system is best characterized by an imbalance of these immune cells. Other immune cells including lymphoid cells related to adaptive immunity are reduced in number while myeloid cells and inflammatory pathologies are increased. Many believe that stem cells may be the cause of this imbalance.

Apr 11, 2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Posted by in category: biotech/medical

Scientists at Duke-NUS Medical School have uncovered why some pancreatic and colorectal cancers fail to respond to Wnt inhibitors, a promising new class of cancer drugs currently under development for these cancers. Their discovery, published in Science Advances, not only offers a new cancer therapy target but also a potential screening tool to identify those patients who will not benefit from this new therapy once it becomes available.

Apr 11, 2024

CAR T Cell Therapies Last Longer, Work Better with FOXO1 Protein

Posted by in category: biotech/medical

New research shows that FOXO1 is required for memory in T cells and associated with more durable clinical responses to CAR T cell therapy.

Apr 11, 2024

Faster aging linked to cancer rates in young adults, study finds

Posted by in categories: biotech/medical, life extension

Researchers from Washington University School of Medicine suggest accelerated biological aging may be driving early-onset cancer rates in young people.

Apr 11, 2024

Breakthrough Parkinson’s Gene Discovery Sheds Light on Evolutionary Origin

Posted by in categories: biotech/medical, neuroscience

Parkinson’s disease is a neurodegenerative movement disorder that progresses relentlessly. It gradually impairs a person’s ability to function until they ultimately become immobile and often develop dementia. In the U.S. alone, over a million people are afflicted with Parkinson’s, and new cases and overall numbers are steadily increasing.

There is currently no treatment to slow or halt Parkinson’s disease. Available drugs don’t slow disease progression and can treat only certain symptoms. Medications that work early in the disease, however, such as Levodopa, generally become ineffective over the years, necessitating increased doses that can lead to disabling side effects.

Continue reading “Breakthrough Parkinson’s Gene Discovery Sheds Light on Evolutionary Origin” »

Apr 11, 2024

Testing drugs on mini-cancers in the lab may reveal best treatment

Posted by in categories: biotech/medical, innovation

The next innovation in cancer treatment could be to test all possible drugs on thousands of miniature versions of a person’s tumour, grown in the lab, to see which works the best. The technique, sometimes called drug sensitivity testing, may have already helped a few children with advanced cancer live for longer than the standard approach.

It could eventually become routinely used for everyone with cancer, says Diana Azzam at Florida International University in Miami. “I would say it will help guide treatments in any [cancer], whether it’s aggressive or not.”

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