The US space agency believes it can put humans on the Red Planet within 25 years, but the technological and medical hurdles are immense. Current latest trending Philippine headlines on science, technology breakthroughs, hardware devices, geeks, gaming, web/desktop applications, mobile apps, social media buzz and gadget reviews.
Researchers from the Kapahi Lab at the Buck Institute for Research on Aging have shown in a new study that increased intestinal permeability is caused by the age-related loss of epithelial cells that form the gut membrane [1].
As we age, the integrity of the gut membrane declines, and it becomes more permeable; this is known as “leaky gut” and is thought to contribute to the background of low-grade chronic inflammation known as inflammaging [2]. One emerging theory is that loss of gut membrane integrity is the origin of inflammaging, the place where age-related chronic inflammation begins. Inflammaging precedes many age-related diseases, including atherosclerosis, arthritis, hypertension, and cancer [3–5].
The new study suggests that caloric restriction, or caloric restriction mimetics, may help to prevent the increase of gut permeability in humans and has the potential to increase healthspan, which is the period of life we spend free from illness.
Privacy advocates have raised concerns about patients’ data after Google said it would take control of its subsidiary DeepMind’s healthcare division.
Google, which acquired London-based artificial intelligence lab DeepMind in 2014, said on Tuesday that the DeepMind Health brand, which uses NHS patient data, will cease to exist and the team behind its medical app Streams will join Google as part of Google Health.
It comes just months after DeepMind promised never to share data with the technology giant and an ethics board raised concerns over its independence.
Inspiration for game-changing science can seemingly come from anywhere. A moldy bacterial plate gave us the first antibiotic, penicillin. Zapping yeast with a platinum electrode led to a powerful chemotherapy drug, cisplatin.
For Dr. Andrew Pelling at the University of Ottawa, his radical idea came from a sci-fi cult classic called The Little Shop of Horrors. Specifically, he was intrigued by the movie’s main antagonist, a man-eating plant called Aubrey 2.
What you have here is a plant-like creature with mammalian features, said Pelling at the Exponential Medicine conference in San Diego last week. “So we started wondering: can we grow this in the lab?”
“We’re going to get these massive pools of sequenced genomic data,” Metzl said. “The real gold will come from comparing people’s sequenced genomes to their electronic health records, and ultimately their life records.” Getting people comfortable with allowing open access to their data will be another matter; Metzl mentioned that Luna DNA and others have strategies to help people get comfortable with giving consent to their private information. But this is where China’s lack of privacy protection could end up being a significant advantage.
To compare genotypes and phenotypes at scale—first millions, then hundreds of millions, then eventually billions, Metzl said—we’re going to need AI and big data analytic tools, and algorithms far beyond what we have now. These tools will let us move from precision medicine to predictive medicine, knowing precisely when and where different diseases are going to occur and shutting them down before they start.
But, Metzl said, “As we unlock the genetics of ourselves, it’s not going to be about just healthcare. It’s ultimately going to be about who and what we are as humans. It’s going to be about identity.”
Miniaturized semiconductor devices with energy harvesting features have paved the way to wearable technologies and sensors. Although thermoelectric systems have attractive features in this context, the ability to maintain large temperature differences across device terminals remains increasingly difficult to achieve with accelerated trends in device miniaturization. As a result, a group of scientists in applied sciences and engineering has developed and demonstrated a proposal on an architectural solution to the problem in which engineered thin-film active materials are integrated into flexible three-dimensional (3D) forms.
The approach enabled efficient thermal impedance matching, and multiplied heat flow through the harvester to increase efficient power conversion. In the study conducted by Kewang Nan and colleagues, interconnected arrays of 3D thermoelectric coils were built with microscale ribbons of the active material monocrystalline silicon to demonstrate the proposed concepts. Quantitative measurements and simulations were conducted thereafter to establish the basic operating principles and key design features of the strategy. The results, now published on Science Advances, suggested a scalable strategy to deploy hard thermoelectric thin-films within energy harvesters that can efficiently integrate with soft material systems including human tissue to develop wearable sensors in the future.
Thermoelectric devices provide a platform to incorporate ubiquitous thermal gradients that generate electrical power. To operate wearable sensors or the “Internet of Things” devices, the temperature gradient between the surrounding environment and the human body/inanimate objects should provide small-scale power supplies. Continued advances in the field focus on aggressive downscaling of power requirements for miniaturized systems to enhance their potential in thermoelectric and energy harvesting applications. Integrated processors and radio transmitters for example can operate with power in the range of subnanowatts, some recent examples are driven via ambient light-based energy harvesting and endocochlear potential. Such platforms can be paired with sensors with similar power to enable distributed, continuous and remote environmental/biochemical monitoring.
MORGANTOWN — World-leading brain experts at West Virginia University’s Rockefeller Neuroscience Institute are celebrating the historic breakthrough Alzheimer patients around the global have been waiting for.
“For Alzheimer’s, there’s not that many treatments available despite hundreds of clinical trials over the past two decades and billions of dollars spent,” said Dr. Ali Rezai, a neurosurgeon at WVU who led the team of investigators that successfully performed a phase II trial using focused ultrasound to treat a patient with early stage Alzheimer’s.
The WVU team tested the innovative treatment in collaboration with INSIGHTEC, an Israeli medical technology company. Earlier this year, INSIGHTEC was approved by the U.S. Food and Drug Administration to begin a phase II clinical trial of the procedure and selected the WVU Rockefeller Neuroscience Institute as the first site in the United States for the trial.
Scientists are now closer than ever to being able to use graphene as a superconductor – to conduct electricity with zero resistance – making it useful for developing energy efficient gadgets, improving medical research, upgrading power grids, and much more besides.
The key to the new approach is heating a silicon carbide (SiC) crystal, itself a superconductor, until the silicon atoms have all evaporated. This leaves two graphene layers on top of each other in a way that, in certain conditions, offers no resistance to electrical current.
A similar dual-layer approach was also successfully used to turn graphene into a superconductor earlier this year. The difference here is the layers don’t have to be carefully angled on top of each other, which should make it easier to reproduce at scale.