Lifeboat Foundation

Another link on diet/healthspan.

Studies by Monash Biomedicine Discovery Institute (BDI), have provided a new understanding into the roles two essential amino acids play in metabolic health, which may help scientists in the fight against obesity.

Led by Dr. Adam Rose, the recent finding, published in Nature Communications, shows that by reducing the amount of two amino acids —threonine and tryptophan—in young healthy mice, they were able to burn more calories than they consumed, without calorie reduction, keeping them lean and healthy and without the side-effect of lower muscle mass. A low-threonine diet even protected mice that were morbidly obese and prone to developing type 2 diabetes.

Continue reading “Essential components of dietary restriction revealed” »

A Minneapolis manufacturing company whose plant was set on fire by rioters plans to leave the city, saying that city officials afforded them no assistance in handling the destruction.

“They don’t care about my business,” 7-Sigma Inc.’s president and owner, Kris Wyrobek, told The Star Tribune about Minneapolis public officials. “They didn’t protect our people. We were all on our own.”

The 7-Sigma plant in south Minneapolis, which the company has maintained since 1987, shut down several hours early around 7 p.m. instead of 11 p.m. as a precautionary measure on the first night of rioting. The company manufactures several products, including rollers for high-speed printing presses and medical training mannequins.

The personal genomics and biotechnology company 23andMe is perhaps best known for its home DNA testing kits, whereby consumers can learn about their genetic make-up or ancestry.

However, after the COVID-19 outbreak was declared a global pandemic, the company switched gears and looked to see how their gene testing services could offer a helping hand in understanding the disease’s pathophysiology.

One aspect of COVID-19 that has puzzled scientists and clinicians alike is why, when infected with SARS-CoV-2, do some patients display mild to moderate symptoms (or no symptoms at all), whereas other patients develop severe symptoms that can prove fatal?

Their new approach to 3D bioprinting and allows for non-invasive tissue growth and wound healing. It works through injecting bioink cells, the additive material traditionally used in 3D bioprinting, under the skin and using near-infrared light to penetrate the tissue and transfer customizable building designs — like an ear or an abstract shape — to newly injected cells.

The ear began to form in just 20 seconds.

Using a new approach to 3D bioprinting researchers have designed a way to non-invasively grow a wide range of customizable tissue under living skin.

Everyone knows that the great and power omnipresent mushroom that lives across the universe able to survive even in space.

Researchers have elucidated the molecular mechanism of the fungus that turns ants into living zombies. The fungus specifically affects the ants’ neurobiology, odor perception and biological clock. The Utrecht microbiologist Robin Ohm publishes this, together with American and German colleagues, in G3.

The fungus Ophiocordyceps camponoti-floridani can infect ants and manipulate their behavior in a way that is beneficial for fungus growth and transmission. These infected ants are called “zombie ants.” Influenced by the fungus, the ants climb to a high point and bite into a branch, attaching themselves until death. The fungus then digests the ant and forms a fruitbody with which the fungus spreads its spores. The molecular mechanisms behind this behavioral modification are still largely unknown, as in similar parasitic interactions in which the behavior of a host is manipulated.

Continue reading “How a fungus turns ants into zombies” »

MR-compatible graphene fibre microelectrodes enable full activation pattern mapping during simultaneous deep brain stimulation and functional MRI.

Guessing things are about to get dicey.

Texas reported a record-breaking number of COVID-19 hospitalizations Monday as the governor plans to reopen more businesses and double capacity.

Texas Department of State Health Services figures show 1,935 people were admitted as hospital patients for coronavirus-related treatment. That is up from a previous record of 1,888 on May 5.

Continue reading “Texas Reports Record-Breaking COVID-19 Hospitalizations As State Reopens” »

Type: Novel lipid nanoparticle (LNP)-encapsulated mRNA vaccine encoding for a prefusion stabilized form of the Spike (S) protein.

Status: Moderna said May 29 the first patients in both cohorts were dosed in the company’s Phase II trial (NCT04405076) assessing mRNA-1273. The study is designed to evaluate the safety, reactogenicity and immunogenicity of two vaccinations of mRNA-1273, given 28 days apart. plans to enroll 600 healthy participants across two cohorts: 300 adults ages 18–55 years, and 300 ages 55 years and up. Participants will be assigned to placebo, a 50 μg or a 100 μg dose at both vaccinations, and will be followed through 12 months after the second vaccination.

Pharmaceutical companies use the creature’s blue blood to test for contaminants.