Lifeboat Foundation

Circa 2018

Back in July 2018, researchers at Purdue University created the world’s fastest-spinning object, which whipped around at 60 billion rpm – and now that seems like the teacup ride at Disneyland. The same team has now broken its own record using the same technique, creating a new nano-scale rotor that spins five times faster.

Like the earlier version, the whirling object in question is a dumbbell-shaped silica nanoparticle suspended in a vacuum. When it’s set spinning, this new model hit the blistering speed of over 300 billion rpm. For comparison, dentist drills are known to get up to about 500,000 rpm, while the fastest pulsar – which is the speediest-spinning known natural object – turns at a leisurely 43,000 rpm.

Continue reading “Fastest spinning object in the world hits 300 billion rpm” »

Early results in The Lancet on Oxford coronavirus vaccine clinical made by AstraZeneca suggest the COVID-19 vaccine is safe and induces antibodies and T cell response.

The Israeli startup CorNeat Vision has received approval to conduct clinical trials of a synthetic cornea that bio-integrates with the human eye.

The Health Ministry-approved trial of the CorNeat KPro will be run at Beilinson Hospital in Petach Tikva on 10 patients suffering from corneal blindness who are either not candidates for or have experienced one or more failed cornea transplants, the company announced last week.

Yesterday, Regeneron Pharmaceuticals, with the U.S. National Institute of Allergy and Infectious Diseases (NIAID), announced it was launching Phase III trials of REGN-COV2, the company’s two-antibody cocktail for the treatment and prevention of COVID-19. Today, it announced that it had received a $450 million contract to manufacture and supply the antibody cocktail as part of Operation Warp Speed from the Biomedical Advanced Research and Development Authority (BARDA).

BARDA is part of the Office of the Assistant Secretary for Preparedness and Response at the U.S. Department of Health and Human Services. The contract was also with the Department of Defense Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense.

A Phase I trial in 30 hospitalized and non-hospitalized patients with COVID-19 received a positive review from the Independent Data Monitoring Committee.

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While the issue of aging and DNA methylation is an area that is well-studied, modifications of DNA to reduce or reverse aging remains an area in need of exploration. Studies in mice utilizing interventions such as caloric restriction and the drug rapamycin have reversed and/or slowed age-related DNA methylation by up to 40%. Understanding the cross-species aging based on similar DNA behaviors may open more doors to investigating therapeutics to minimize lifetime risks of age-related illnesses such as Alzheimer’s disease and cancers.

A recent study published in Cell Systems sought to debunk one of the most common myths about dogs: much to our surprise, one “dog year” does not equal seven “human years.” As described in a recent Forbes piece by Sara Tabin, the relationship between dog years and human years is not linear, but is based on a logarithmic formula. The research group, based at the University of California, San Diego (UCSD), created the formula as follows:

Age in human years = 16 ln(age in dog years) +31. (ln means “natural logarithm).

Continue reading “The Answer To Anti-Aging Therapies May Lie In Your Aging Dog” »

https://youtube.com/watch?v=KxGWye97ytk

Scientists and historians working at McMaster University, the Mütter Museum and the University of Sydney have pieced together the genomes of old viruses that were used as vaccination strains during and after the American Civil War ultimately leading to the eradication of smallpox.

Smallpox was one of the most devastating viral diseases ever to strike humankind, killing about three out of every 10 people who were infected. Those who survived were frequently disabled, blind or disfigured.

Continue reading “Scientists Trace Origin of Smallpox Vaccine Strains Used in the Civil War” »

Summary: APOEe4, a gene associated with Alzheimer’s disease risk, doesn’t appear to directly affect memory performance or brain activity in older adults without cognitive impairment. However, the gene does seem to influence brain regions and systems that older at-risk adults activate to support successful memory recall.

Source: McGill University

Researchers at McGill University and the Douglas Mental Health University Institute, in collaboration with the StoP-AD Center, have published a new paper in the Journal of Alzheimer’s Disease, examining how a known genetic risk factor for late-onset Alzheimer’s disease (AD) influences memory and brain function in cognitively intact older adults with a family history of AD.

Nanoscale thermal physics guarantees our decline, no matter how many diseases we cure.

The biotech Mesoblast is starting a compassionate use study of its stem cell product for kids with a severe offshoot of COVID-19.

The cellular drug in this case is remestemcel-L (more below).

While most children fare better than adults in dealing with COVID-19, the rare subset of kids with COVID-19 for this study have more severe disease than the average COVID patient and some die.