Multiple human organ chips that quantitatively predict drug pharmacokinetics may offer better, accelerated drug testing.
My latest blood test results are in-how’s my biological age?
In the video I discuss my dietary approach prior to my latest blood test, the blood test results, and my plan to improve them going forward.
A breakthrough COVID-19 treatment using pineapples has been accidently discovered by Australian scientists, but how does it compare to a vaccine?
Angela Cox speaks with Professor David Morris, the man behind the discovery.
“Observations of metastasising cells revealed something intriguing—a high level of something called methylmalonic acid (MMA), a metabolic byproduct that appears to accumulate as we get older.”
“So how does MMA induce these changes in cancer cells? The key seems to be in a sort of reprogramming that “switches on” a gene called SOX4.
Prior research has shown SOX4 encourages cancer cells to become more aggressive and prone to metastasis.
Continue reading “Study finds cancer-boosting culprit that multiplies with age” »
Research is showing a strong link between handgrip strength, walking speed, and cognition, indicating how improved physical health could boost elderly minds.
Based at Barwon Health, in the heart of Geelong’s clinical health precinct, researchers are working to identify the risk factors —such as changes in muscle mass, muscle strength and physical performance—for developing sarcopenia (loss of muscle mass, strength and function with advancing age) across the lifespan.
This testing involves the Geelong Osteoporosis Study (GOS) which began in the early 1990s, gathering adult participants from the electoral roll in the Barwon Statistical Division. During recent follow-up testing, researchers also measured cognitive function through a computer-based program, in tandem with physical health evaluations.
For decades, greater than 60% of the human genome was believed to be “junk DNA” that served little or no purpose in the course of human development. Recent research by Colorado State University is challenging this notion to show that junk DNA might be important after all.
A new study, published on June 5 in Aging Cell, found that a portion of noncoding genetic material, called repetitive element transcripts, might be an important biomarker of the aging process.
Tom LaRocca, an assistant professor in the Department of Health and Exercise Science and faculty member in the Columbine Heath Systems Center for Healthy Aging at CSU, led the study to investigate a growing body of evidence that repetitive elements—transposons and other sequences that occur in multiple copies in the human genome —may become active over time as we age.
Aubrey interviewed by, um, alien scientists.
Our conversation covers the importance of non-academic institutions in science, strategies for combating for repair the damage of aging, and an exploration of how extending human lifespan will change the Earth. In Dr. de Gray’s perspective, age-related decline is a medical problem like any other that can be treated and cured by cutting edge technology. He’s devoted himself to this pursuit as a founder of the SENS Research Foundation, the Methuselah Foundation, and the medical startup AgeX.
Continue reading “A Future Without Aging — Dr. Aubrey de Grey” »
Light is notoriously fast. Its speed is crucial for rapid information exchange, but as light zips through materials, its chances of interacting and exciting atoms and molecules can become very small. If scientists can put the brakes on light particles, or photons, it would open the door to a host of new technology applications.
Now, in a paper published on Aug. 17, in Nature Nanotechnology, Stanford scientists demonstrate a new approach to slow light significantly, much like an echo chamber holds onto sound, and to direct it at will. Researchers in the lab of Jennifer Dionne, associate professor of materials science and engineering at Stanford, structured ultrathin silicon chips into nanoscale bars to resonantly trap light and then release or redirect it later. These “high-quality-factor” or “high-Q” resonators could lead to novel ways of manipulating and using light, including new applications for quantum computing, virtual reality and augmented reality; light-based WiFi; and even the detection of viruses like SARS-CoV-2.
“We’re essentially trying to trap light in a tiny box that still allows the light to come and go from many different directions,” said postdoctoral fellow Mark Lawrence, who is also lead author of the paper. “It’s easy to trap light in a box with many sides, but not so easy if the sides are transparent—as is the case with many Silicon-based applications.”
Hong Kong’s biggest container port facility Kwai Tsing Container Terminals has been linked to around 65 coronavirus infection cases, Bloomberg reported.
According to local media outlets, the virus was most probably picked up from communal resting facilities and dormitories, where social distancing measures are difficult to implement as dozens of workers can be confined to the same place at the same time.
Most of the workers were linked to Wang Kee Port Operation Services Ltd. and were predominantly asymptomatic. Around 100 workers have reportedly been quarantined.
Newswise — Most of modern medicine has physical tests or objective techniques to define much of what ails us. Yet, there is currently no blood or genetic test, or impartial procedure that can definitively diagnose a mental illness, and certainly none to distinguish between different psychiatric disorders with similar symptoms. Experts at the University of Tokyo are combining machine learning with brain imaging tools to redefine the standard for diagnosing mental illnesses.
“Psychiatrists, including me, often talk about symptoms and behaviors with patients and their teachers, friends and parents. We only meet patients in the hospital or clinic, not out in their daily lives. We have to make medical conclusions using subjective, secondhand information,” explained Dr. Shinsuke Koike, M.D., Ph.D., an associate professor at the University of Tokyo and a senior author of the study recently published in Translational Psychiatry.
“Frankly, we need objective measures,” said Koike.
