Lifeboat Foundation

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With fall and winter holidays coming up, many will be pondering the relationship between food and sleep. Researchers led by Professor Masashi Yanagisawa at the University of Tsukuba in Japan hope they can focus people on the important middlemen in the equation: bacterial microbes in the gut. Their detailed study in mice revealed the extent to which bacteria can change the environment and contents of the intestines, which ultimately impacts behaviors like sleep.

The experiment itself was fairly simple. The researchers gave a group of mice a powerful cocktail of antibiotics for four weeks, which depleted them of intestinal microorganisms. Then, they compared intestinal contents between these mice and control mice who had the same diet. Digestion breaks food down into bits and pieces called metabolites. The research team found significant differences between metabolites in the microbiota-depleted mice and the control mice. As Professor Yanagisawa explains, “we found more than 200 metabolite differences between mouse groups. About 60 normal metabolites were missing in the microbiota-depleted mice, and the others differed in the amount, some more and some less than in the control mice.”

The team next set out to determine what these metabolites normally do. Using metabolome set enrichment analysis, they found that the biological pathways most affected by the antibiotic treatment were those involved in making neurotransmitters, the molecules that cells in the brain use to communicate with each other. For example, the tryptophan–serotonin pathway was almost totally shut down; the microbiota-depleted mice had more tryptophan than controls, but almost zero serotonin. This shows that without important gut microbes, the mice could not make any serotonin from the tryptophan they were eating. The team also found that the mice were deficient in vitamin B6 metabolites, which accelerate production of the neurotransmitters serotonin and dopamine.

A material that mimics human skin in strength, stretchability and sensitivity could be used to collect biological data in real time. Electronic skin, or e-skin, may play an important role in next-generation prosthetics, personalized medicine, soft robotics and artificial intelligence.

“The ideal e-skin will mimic the many natural functions of human skin, such as sensing temperature and touch, accurately and in real time,” says KAUST postdoc Yichen Cai. However, making suitably flexible electronics that can perform such delicate tasks while also enduring the bumps and scrapes of everyday life is challenging, and each material involved must be carefully engineered.

Most e-skins are made by layering an active nanomaterial (the sensor) on a stretchy surface that attaches to human skin. However, the connection between these layers is often too weak, which reduces the durability and sensitivity of the material; alternatively, if it is too strong, flexibility becomes limited, making it more likely to crack and break the circuit.

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They can check you in and deliver orange juice to your hotel room, answer your questions about a missing package, whip up sushi and pack up thousands of subscription boxes. And, perhaps most importantly, they are completely immune to Covid-19. While people have had a hard time in the coronavirus pandemic, robots are having a moment.

The Covid-19 pandemic has left millions of Americans unemployed – disproportionately those in the service industries where women and people of color make up the largest share of the labor force. In October, 11 million people were unemployed in the US, compared with about 6 million people who were without a job during the same time last year.

Sales for the category have exploded as the pandemic disrupts business as usual. Is this because people are turning away from animal-based eating, or is it keeping with the segment’s trends?

The farm has been placed under quarantine, and staff have been told to self-isolate.

Over the past few decades, artificial intelligence (AI) tools have been used to analyze data or complete basic tasks in an increasing number of fields, ranging from computer science to manufacturing, medicine, physics, biology and even artistic disciplines. Researchers at University of Michigan have recently been investigating the use of artificial intelligence (AI) in architecture. Their most recent paper, published in the International Journal of Architectural Computing, specifically explores the potential of AI as a tool to create new architectural designs.

“My partner, Sandra Manninger, and myself, have a long-standing obsession with the idea to cross pollinate the fields of architecture and AI,” Matias del Campo, one of the researchers who carried out the study, told Tech Xplore. “We first got in touch with AI research in 1998, when we were introduced to the OFAI (The Austrian Institute of Artificial Intelligence) through a mutual friend, Dr. Arthur Flexer and we held the first course in Machine Learning for Architecture at the University of Applied Arts in Vienna, in 2006.”

Several years after they first became interested in the potential uses of AI in architecture, del Campo and Manninger started collaborating with the Robotics Department at University of Michigan. Working with Jessy Grizzle, the department’s director, and Alexandra Carlson, one of her Ph.D. students, they were able to significantly expand their research. Their study featured in the International Journal of Architectural Computing is the latest of a series of research efforts in which they investigated the use of AI techniques for designing architectural solutions.

Methylation definition at 5:05, 27:20 a lil about reprogramming, 32:00 q&a, 47:44 Aubrey chimes in, 57:00 Keith Comito(and other throughout)

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