Lifeboat Foundation

Stress management.

Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well as others. In a few cases, the cause is genetic. In humans, mutations in the OPHN1 gene cause a rare X-linked disease that includes poor stress tolerance. Cold Spring Harbor Laboratory (CSHL) Professor Linda Van Aelst seeks to understand factors that cause specific individuals to respond poorly to stress. She and her lab studied the mouse gene Ophn1, an analog of the human gene, which plays a critical role in developing brain cell connections, memories, and stress tolerance. When Ophn1 was removed in a specific part of the brain, mice expressed depression-like helpless behaviors. The researchers found three ways to reverse this effect.

To test for stress, the researchers put mice into a two-room cage with a door in between. Normal mice escape from the room that gives them a light shock on their feet. But animals lacking Ophn1 sit helplessly in that room without trying to leave. Van Aelst wanted to figure out why.

Continue reading “Reversing a Genetic Cause of Poor Stress Tolerance” »

The unprecedented study involves using the gene-editing technique CRISPR to edit a gene while it’s still inside a patient’s body. In exclusive interviews, NPR talks with two of the first participants.

The most recent Apple user survey suggests that a blood glucose monitoring feature is definitely on the table.

A team of international researchers, including Dr. Rich Crane from the Camborne School of Mines, University of Exeter, have developed a new method to extract metals, such as copper, from their parent ore body.

The research team has provided a proof of concept for the application of an electric field to control the movement of an acid within a low permeability copper-bearing ore deposit to selectively dissolve and recover the metal in situ.

This is in contrast to the conventional approach for the mining of such deposits where the material must be physically excavated, which requires removal of both overburden and any impurities within the ore (known as gangue material).

7:01 they talk about Church’s comments of ending aging by 2030. Also this appears to be a part one.

In this video Professor Church talks about his theory of aging and touches on his ideas on the future of aging.

Continue reading “My Theory & The Future Of Aging | Prof George Church Interview Series Episode 1” »

Excerpts from an interview with Dr. María Blasco, Director of the Spanish National Cancer Research Center (CNIO), where she covers how telomeres shortening induce aging, how artificially lenghtening telomeres has proven to extend lifespan in animal models like mice, and what the impact will be in human health and lifespan once the techniques (gene therapies) get effectively translated into humans.

The interview took place on May 6, 2021 as part of a program organized by the Madrid Planetarium, to contribute to a better orientation of the students of the last years of high school when deciding which university studies further engage.

Continue reading “María Blasco sobre retrasar el envejecimiento y extender la vida (with S/T in English)” »

It sounds too good to be true, a vaccine that can protect against future virus variants. But governments around the world are keen to learn more.

I still don’t get how there seems to be No organized effort anywhere to achieve the ability to 3D print a perfect genetic match of all organs by 2025 — 2030. You would think some government somewhere would want to work round the clock on this.

NIBIB-funded engineers at the University of Buffalo have fine-tuned the use of stereolithography for 3D printing of organ models that contain live cells. The new technique is capable of printing the models 10–50 times faster than the industry standard-;in minutes instead of hours-; a major step in the quest to create 3D-printed replacement organs.

Conventional 3D printing involves the meticulous addition of material to the 3D model with a small needle that produces fine detail but is extremely slow —taking six or seven hours to print a model of a human part, such as a hand, for instance. The lengthy process causes cellular stress and injury inhibiting the ability to seed the tissues with live, functioning cells.

Continue reading “New technique can print life-like organ models in minutes” »

https://www.youtube.com/watch?v=UudjpTgB3K8&feature=share

0:00 — Title.
0:35 — Into.
1:15 — Super People of The Future.
1:46 — Neal VanDeree ‘Living Long Healthy Lives Will be Possible’ — https://www.churchofperpetuallife.org/ — https://www.youtube.com/user/COPL18
3:24 — Dr. Bill Andrews ‘Super Wonderful Future’ — https://www.sierrasci.com/
6:27 — Selim Bakırcı ‘1000 years long life’
6:58 — Rodrigo Guinea ‘Great Responsibility’ — https://www.linkedin.com/in/rodguinea/
9:22 — Significant Research.
9:40 — Significant Research — Liz Parrish — https://bioviva-science.com/
10:44 — Significant Research — Brent Nally — https://longevityplan.net/ — https://www.linkedin.com/in/brentnally/ — https://www.youtube.com/user/BrentAltonNally.
13:10 — Significant Research — Cain Hillier — https://www.linkedin.com/in/cain-hillier-50571a18a/
14:43 — Significant Research — Chris Curwen — https://www.linkedin.com/in/chris-curwen-67144b169/
17:16 — The Threshold Times.
18:41 — The Threshold Times — Brent Nally.
21:35 — The Threshold Times — Chris Curwen
24:25 — The Threshold Times — Liz Parrish.
26:21 — The Threshold Times — Nicolas Chernavsky
https://www.linkedin.com/in/nicolas-chernavsky-25265835/ — https://www.youtube.com/channel/UCUASjdn96BRlGVytmbDgRRA
27:00 — The Threshold Times — Josh Martin.
27:42 — The Threshold Times — Cain Hillier.
28:50 — The Threshold Times — Vikram Pandya — https://www.linkedin.com/in/vikrampandya/
31:24 — Ageing Is a Disease.
32:49 — Ageing Is a Disease — Neal VanDeree.
34:09 — Ageing Is a Disease — Dr. Bill Andrews.
37:48 — Ageing Is a Disease — Liz Parrish.
39:28 — Ageing Is a Disease — Brent Nally.
42:10 — Ageing Is a Disease — Aaron King.
44:44 — Ageing Is a Disease — Lukas Vismantas — https://www.linkedin.com/in/lukas-vismantas/?originalSubdomain=dk.
46:07 — Ageing Is a Disease — Cain Hillier.
48:02 — Ageing Is a Disease — Chris Curwen.
50:23 — Ageing Is a Disease — Nicolas Chernavsky.
52:49 — The Big Times.
54:40 — The Big Times — Dr. Bill Andrews.
56:52 — The Big Times — Liz Parrish.
59:16 — The Big Times — Brent Nally.
01:03:50 — The Big Times — Nicholas Mohnacky — https://www.bundleiq.com/ — https://www.linkedin.com/in/mohnacky/
01:05:00 — The Big Times — Bolek Kerous — https://www.linkedin.com/in/bolekkerous/ — https://www.youtube.com/channel/UCSpv8MA3xPskco9qdIBeNuQ
01:08:24 — The Big Times — Nicolas Chernavsky.
01:08:58 — The Big Times — Chris Curwen.
01:09:48 — The Big Times — Nicolas Chernavsky.
01:11:19 — The Big Times — Jeremy Rumble — https://www.linkedin.com/in/jeremy-rumble-42910b38/
01:12:22 — The Big Times — Jakub Czubak — https://www.linkedin.com/in/jakub-czubak-603624a9/
01:14:20 — The Big Times — Josh Martin.
01:14:50 — The Big Times — Nicolas Chernavsky.
01:20:15 — The Big Times — Brent Nally.
01:22:09 — Ending.

Omitting natural disasters like an asteroid smashing Earth or a volcano eruption we can say that improving human health and condition is the most important safety case/concern and the fundamental thing to consider and accomplish on our way to be super cosmic humanity. Significant health improvements will free us from all diseases, allow us to develop superhuman intelligence, let us totally self-realize, and consequently, help realize the infinity in the matter for the common good. However intensively we focus on intelligence, it is not possible to experience its natural consequence or the next level of its advancement/evolution if there is no good health. Coherent and consistent collective mind continuum experience is not possible without super health (Healthy life that is free from the danger of uncontrollable death). Our bodies are short-timed and not strong enough to hold up the Earth-Gravity-Geometry sized/adjusted thoughts that are necessary to naturally manage and effectively inhabit our planet.

Continue reading “Super Long HealthSpans: In The Making” »