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Category: biotech/medical – Page 1,356

A 1.3-micrometer-thin elastic conductor for wearable and implantable devices

In recent years, engineers have been working to develop increasingly sophisticated and smaller electronic components that could power the devices of the future. This includes thin and stretchable components that could be easily worn on the skin or implanted inside the human body.

Researchers at RIKEN, Nanyang Technological University, National University of Singapore, University of Tokyo, and other institutes in Japan, Singapore and China have recently realized a new, elastic electrical conductor that is 1.3-micrometers thin. This conductor, introduced in a paper published in Nature Electronics, could advance the development of both wearable and implantable sensors.

“Ultrathin electronic devices can form a conformal interface with curved surfaces, are not perceivable by human when wearing, and do not induce strong foreign body rejection (FBR) when implanted in animals,” Zhi Jiang, one of the researchers who carried out the study, told TechXplore.

Gene expression data point to exercise as the most effective treatment for Alzheimer’s disease

An analysis of 22 large-scale gene expression datasets pointed to exercise and activity in general as the most effective theoretical treatment for reversing gene expressions typical of Alzheimer’s disease. Fluoxetine, a well-known antidepressant, also showed effect, particularly when combined with exercise. Curcumin showed positive effects as well. The study was published in Scientific Reports.

Alzheimer’s disease is a complex neurodegenerative disorder that affects multiple brain regions. It is the most common disease that causes dementia and is very difficult to treat. In the course of the disease, abnormal collections of proteins called tau accumulate inside neurons.

Another type of protein clumps together to form so-called amyloid plaques that collect between neurons and disrupt cell functions. These and other changes harm the functioning of the brain across different regions and lead to dysfunction and death of brain cells.

Parrots Keep Attacking Poppy Farms To Get High On Opium

They’re so much like humans. Hopefully this doesn’t hurt them in the long term.

Farms in India have reached out to the authorities after repeatedly being attacked by opium-addicted parrots.

Farmers in Madhya Pradesh say their opium crops are being ruined by parrots who keep returning to raid their farms in an attempt to get high. The farmers have been guarding the fields day and night to protect their poppies, but the birds are willing to risk it all to get their beaks on the opium, which is being farmed for medical purposes.

Playing loudspeakers has also failed to rid the farms of the birds, whose opium problem is too far developed to let a bit of noise deter them.

Researchers Turn Cancer Cells Into Less Harmful Cell Types

Cancer cells are incredibly adaptable, much like stem cells. Researchers from the University of Basel have discovered substances that artificially mature breast cancer cells of the very aggressive triple-negative subtype and transform them into a state that is similar to normal cells.

Cancer occurs when cells grow uncontrollably and spread to other organs. Cancer cells are quite different from normal ones. Cancer cells are known for their remarkable adaptability to varied settings in the body as well as drug treatments. They resemble stem cells or cells at an early stage of development in this regard.

The prospect of artificially maturing (or, more accurately, differentiating) breast cancer cells as a strategy to transform them into a more normal kind of cell has been explored by researchers at the University of Basel and the University Hospital Basel.

Bacteria From An Olympic Weightlifter Improves Muscle Mass And Physical Function (In Mice)

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Neuralink NIGHTMARE: Elon’s Brain Chip Trials Are A Total Horror Show

Elon Musk’s Neuralink is under federal investigation for potential animal-welfare violations after staff complaints about rushed animal testing. Ana Kasparian discusses on The Young Turks. Watch TYT LIVE on weekdays 6–8 pm ET. http://youtube.com/theyoungturks/live.

“Elon Musk’s Neuralink, a medical device company, is under federal investigation for potential animal-welfare violations amid internal staff complaints that its animal testing is being rushed, causing needless suffering and deaths, according to documents reviewed by Reuters and sources familiar with the investigation and company operations.

Neuralink Corp is developing a brain implant it hopes will help paralyzed people walk again and cure other neurological ailments. The federal probe, which has not been previously reported, was opened in recent months by the U.S. Department of Agriculture’s Inspector General at the request of a federal prosecutor, according to two sources with knowledge of the investigation. The probe, one of the sources said, focuses on violations of the Animal Welfare Act, which governs how researchers treat and test some animals.”

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Covid Variant BQ.1.1 Resistant To All Monoclonal Antibody Treatments

If you’re expecting monoclonal antibody treatments to save you from getting more severe outcomes like death should you get Covid-19, it may be time to rethink that strategy. A letter published in The Lancet Infectious Diseases journal on November 18 detailed how many of the currently spreading Omicron subvariants, namely the BA.4.6, BA.2.75.2, and BJ.1 ones, appear to be resistant to most available monoclonal antibody treatments. And the BQ.1.1 Omicron subvariant, which has become one of the two dominant versions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the U.S., seems resistant to all of the available monoclonal antibody treatments. Yes, all of them, as in every single one.

BQ certainly doesn’t stand for “be quiet,” as the BQ.1.1 subvariant is now causing a commotion, being responsible for an estimated 24.2% of all new reported Covid-19 cases over the past week while the not-too-different BQ.1 subvariant has been the culprit behind 25.5% of them, according to the Centers for Disease Control and Prevention (CDC). If you do the math, that means that these two Omicron subvariants are now comprising over half of all reported Covid-19 cases, meaning that they have overtaken the BA.5 as the “alpha-dog” of SARS-CoV-2 versions. Therefore, you can probably no longer rely on any type of monoclonal antibody should you get Covid-19. That’s certainly bad news for anyone not able to get enough protection from Covid-19 vaccination such as those who have very weak immune systems.

You know that 1997 Backstreet Boys song that goes “everybody, yeah?” Well, looks like the latest 2022 Covid-19 coronavirus Omicron subvariants have been going, “antibody, no-oh.” So much for the argument that other Covid-19 precautions are not needed because monoclonal antibodies are available. Even back in 2020 and 2021 when monoclonal antibody treatments seemed to work against the then-circulating previous versions of the virus, such an argument held water about as well as a Brillo pad thong since relying on any single Covid-19 precaution or treatment has always been a foolhardy approach. Doing so was akin to telling someone, “since you have underwear on, why do you need pants or a skirt or a kilt?” Ever since the start of the pandemic, real pandemic experts have continued to advocate for more of a “Swiss cheese” approach that entails always layering on different Covid-19 interventions simultaneously because each single intervention has its holes.

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