Preclinical and clinical evidence for exercise as a senescence-targeting therapy and areas needing further investigation are discussed.

Will humans be able to grow replacement organs? LyGenesis aims to prove it can be done.
LyGenesis is a biomedical company hoping to deliver a technology that will allow patients to grow functioning organs. If successful the company’s cell therapies will disrupt organ transplantation allowing patients to grow their own. Instead of surgery, a person will do what some amphibians and reptiles do today when they lose a limb or tail.
The company is using the inherent nature of lymph nodes and their evolutionary function, turning them into rapid bioreactors. Our lymph nodes already do this when they produce infection-fighting T-cells. But LyGenesis’ therapies turn donated organ cells into biofactories that can become a source for producing viable organs in multiple patients. The only minimally invasive procedure involved is the engrafting of the cells into a patient’s lymph nodes to begin the process of organ development.
The Indian Institute of Technology (IIT) Madras has announced a collaborative study with the Jet Propulsion Laboratory (JPL), the research hub of central US space agency National Aeronautics and Space Administration (NASA), to study the impact of microorganisms aboard the International Space Station. Observations from the research project will help create medical solutions to aid astronauts in long term human missions in space.
Explaining the observations, Karthik Raman, assistant professor at the department of biotechnology, IIT Madras, said that the collection of microbes, which includes a variety of bacteria and fungi, have occurred over time due to the astronauts that have been aboard the ISS over the past decades.
“Even though the ISS is a highly sterile environment, these microbes can play a big role in the way human presence in a space environment works — which our research work sought to highlight,” Raman said.
Gas stoves in California homes are leaking cancer-causing benzene, researchers found in a new study published on Thursday, though they say more research is needed to understand how many homes have leaks.
In the study, published in Environmental Science and Technology on Thursday, researchers also estimated that over 4 tons of benzene per year are being leaked into the atmosphere from outdoor pipes that deliver the gas to buildings around California — the equivalent to the benzene emissions from nearly 60,000 vehicles. And those emissions are unaccounted for by the state.
The researchers collected samples of gas from 159 homes in different regions of California and measured to see what types of gases were being emitted into homes when stoves were off. They found that all of the samples they tested had hazardous air pollutants, like benzene, toluene, ethylbenzene and xylene (BTEX), all of which can have adverse health effects in humans with chronic exposure or acute exposure in larger amounts.
Harnessing The Power Of Science & Innovation For All — Dr. Anna Laura Ross, Ph.D., Unit Head for Emerging Technologies, Research Prioritization and Support, Science Division, WHO.
Dr. Anna Laura Ross, Ph.D. is the Unit Head for Emerging Technologies, Research Prioritization and Support, in the World Health Organization (WHO) Science Division (https://www.who.int/our-work/science-division), located in Geneva, as well as the Head of the WHO Science Council Secretariat.
Previously at WHO, Dr Ross served as Strategy Technical Manager at Unitaid, their global health initiative that works with partners to bring about innovations to prevent, diagnose and treat major diseases in low-and middle-income countries, with an emphasis on tuberculosis, malaria, and HIV/AIDS and its deadly co-infections, providing strategic and technical support for Unitaid’s strategy, and working to identify the priorities areas for intervention to accelerate innovation for global health.
Dr. Ross has over fifteen years of experience in global health. Her areas of interest are in the field of HIV biomedical research, scientific program coordination, implementation research, and global health policy.
Prior to joining WHO, Dr. Ross served as Head of International Affairs and Scientific Relations at the National Agency for Research on AIDS and Viral Hepatitis (ANRS) in Paris, France.
A collaborative research team co-led by City University of Hong Kong (CityU) has developed a wearable tactile rendering system, which can mimic the sensation of touch with high spatial resolution and a rapid response rate.
The team demonstrated its application potential in a braille display, adding the sense of touch in the metaverse for functions such as virtual reality shopping and gaming, and potentially facilitating the work of astronauts, deep-sea divers and others who need to wear thick gloves.
“We can hear and see our families over a long distance via phones and cameras, but we still cannot feel or hug them. We are physically isolated by space and time, especially during this long-lasting pandemic,” said Dr. Yang Zhengbao, Associate Professor in the Department of Mechanical Engineering of CityU, who co-led the study.
(http://www.pharma.unizg.hr/en/about-us/staff/gordan–lauc, 450.html) is Professor of Biochemistry and Molecular Biology at the University of Zagreb, Faculty of Pharmacy and Biochemistry, and Founder and CEO of Genos Ltd. (https://genos-glyco.com/), a research-intensive SME located in Zagreb, Croatia with core of expertise in molecular genetics and glycomics (The comprehensive study the entire complement of sugars, whether free or present in more complex molecules of an organism) and they perform contract research, contract analysis and service for numerous universities, hospitals and private individuals in Europe and overseas.
Prof. Dr. Lauc also is CSO of GlycanAge LTD (https://glycanage.com/), a company that has developed a ground-breaking test that analyses your personal glycobiome for insights in improving your health and monitoring your biological age, and Co-Director of the Human Glycome Project (https://human-glycome.org/).
Prof. Dr. Lauc graduated with a degree in molecular biology at the University of Zagreb Faculty of Science in 1992, and obtained Ph.D. in Biochemistry and the University of Zagreb in 1995. He got his postdoctoral training at the Institute for Medical Physics and Biophysics in Münster and Johns Hopkins University in Baltimore. Since 1993 he has been employed at the Faculty of Pharmacy and Biochemistry in Zagreb. Between 1998 and 2010 he was also part-time employed at the University of Osijek School of Medicine where he founded a DNA laboratory for the identification of war victims and also served as Vice-Dean for Science between 2001 and 2005.
Prof. Dr. Lauc is author of over 100 research papers published in international journals and six international patents. He was invited to lecture at numerous international conferences, elected for visiting professor at the Johns Hopkins University and in 2011 also inducted in the prestigious Johns Hopkins Society of Scholars. If 2012 he was appointed Honorary Professor at the University of Edinburgh and Adjunct Professor at the Edith Cowan University in Perth.
Prof. Dr. Lauc chaired a number of conferences, including the “European Science Foundation Exploratory Workshop on Glycoscience” which resulted in the creation of the “European Glycoscience Forum”.
Prof. Dr. Lauc was a chairman of the committee that prepared Croatian National Action plan for the increased investment in research in development (2007), and was a member of the National Science Council between 2009 and 2013 and also and President of the National Council for Natural Sciences. He is a President-elect of the International Glycoscience Organization and member of the Steering Committee of the European Glycoscience Forum.
A Brazilian study published in Scientific Reports shows that artificial intelligence (AI) can be used to create efficient models for genomic selection of sugarcane and forage grass varieties and predict their performance in the field on the basis of their DNA.
In terms of accuracy compared with traditional breeding techniques, the proposed methodology improved predictive power by more than 50%. This is the first time a highly efficient genomic selection method based on machine learning has been proposed for polyploid plants (in which cells have more than two complete sets of chromosomes), including the grasses studied.
Machine learning is a branch of AI and computer science involving statistics and optimization, with countless applications. Its main goal is to create algorithms that automatically extract patterns from datasets. It can be used to predict the performance of a plant, including whether it will be resistant to or tolerant of biotic stresses such as pests and diseases caused by insects, nematodes, fungi or bacteria, and or abiotic stresses such as cold, drought, salinity or insufficient soil nutrients.
Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. In most people with the disease — those with the late-onset type symptoms first appear in their mid-60s. In a study from Brigham and Women’s Hospital, scientists found a new contributor to Alzheimer’s disease.