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Deadly dengue virus hijacks mosquito saliva to spread sickness

The saliva of mosquitoes infected with dengue viruses contains a substance that thwarts the human immune system and makes it easier for people to become infected with the potentially deadly viruses, new research published in PLOS Pathogens reveals.

Dengue has spread in recent years to Europe and the southern United States in addition to longstanding hotspots in tropical and subtropical areas such as Southeast Asia, Africa and Latin America. The new discovery, from a University of Virginia School of Medicine scientist and his collaborators, helps explain why the disease is so easily transmitted—and could eventually lead to new ways to prevent infection.

“It is remarkable how clever these viruses are. They subvert mosquito biology to tamp down our immune responses so that infection can take hold,” said Dr. Mariano A. Garcia-Blanco, who recently joined the UVA faculty as chair of the Department of Microbiology, Immunology and Cancer Biology. “There is no doubt in my mind that a better understanding of the fundamental biology of transmission will eventually lead to effective transmission-blocking measures.”

Merging Artificial Intelligence and Physics Simulations To Design Innovative Materials

Max Planck scientists explore the possibilities of artificial intelligence in materials science and publish their review in the journal Nature Computational Science.

Advanced materials become increasingly complex due to the high requirements they have to fulfil regarding sustainability and applicability. Dierk Raabe, and colleagues reviewed the use of artificial intelligence in materials science and the untapped spaces it opens if combined with physics-based simulations. Compared to traditional simulation methods, AI has several advantages and will play a crucial role in material sciences in the future.

Advanced materials are urgently needed for everyday life, be it in high technology, mobility, infrastructure, green energy or medicine. However, traditional ways of discovering and exploring new materials encounter limits due to the complexity of chemical compositions, structures and targeted properties. Moreover, new materials should not only enable novel applications, but also include sustainable ways of producing, using and recycling them.

Post-Singularity Predictions — How will our lives, corporations, and nations adapt to AI revolution?

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DISCLAIMER: This video is not medical, financial, or legal advice. This is just my personal story and research findings. Always consult a licensed professional.

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A new drug-resistant fungus is spreading in hospitals. Is it ‘The Last of Us’ in real life?

“Clinical cases of infections caused by C. auris almost doubled in 2021, according to research published this month in the Annals of Internal Medicine. And the number of cases resistant to echinocandins, the first-line treatment for C. auris infections, tripled. While the fungus generally isn’t a threat for healthy people, it can be dangerous for those with weakened or compromised immune systems, and people using feeding tubes or catheters—in other words, a large proportion of patients in hospitals. The fungus can cause a bloodstream infection whose symptoms include fever, chills, sweats, and low blood pressure. It’s still rare in the U.S., but roughly one in three patients with an invasive infection will die from it; the fungus poses an “urgent threat,” according to the US Centers for Disease Control and Prevention.”


Here’s a scenario that may sound familiar to fans of the postapocalyptic TV drama ‘The Last of Us’: a hard-to-kill fungus is beginning to spread among—and infect—vulnerable populations. Only this time, it’s real.

This Massive Meatball Was Made With Woolly Mammoth DNA

♡,♡!!!


In a sense, the extinct woolly mammoth has returned —as a meatball. On Tuesday, an Australian cultured meat start-up revealed a sphere of lab-grown meat, produced with a DNA sequence from the elephant-like mammal.

But you won’t find this product in grocery stores; the creation is not meant to be eaten, at least for now. Instead, the “mammoth meatball” aims to highlight the environmental impacts of standard agricultural practices and present cultured meat as a viable option for food production down the line.

“We wanted to get people excited about the future of food being different to potentially what we had before,” Tim Noakesmith, a co-founder of Vow, the company behind the meatball, tells Mike Corder of the Associated Press (AP). “We thought the mammoth would be a conversation starter. … What we wanted to do was see if we could create something that was a symbol of a more exciting future that’s not only better for us, but also better for the planet.”

A Disease Reversal Therapy That No Body Try Before

Previously Fahy has reported as much as a 15 year epigenetic clock reset. Again though, this won’t get you beyond your maximum natural limit, but younger and healthier now leads to the next bridge.


Dr Greg Fahy talks about the thymus magic. What are the out of expectation benefits of reprogramming our thymus(Not TRIIM or TRIIM-X) in this short clip.

Gregory M. Fahy is a cryobiologist and biogerontologist, and is also Vice President and Chief Scientific Officer at Twenty-First Century Medicine, Inc. Fahy is the world’s foremost expert in organ cryopreservation by vitrification. Fahy introduced the modern successful approach to vitrification for cryopreservation in cryobiology and he is widely credited, along with William F. Rall, for introducing vitrification into the field of reproductive biology.

Fahy is also a well-known biogerontologist and is the originator and Editor-in-Chief of The Future of Aging: Pathways to Human Life Extension, a multi-authored book on the future of biogerontology. He currently serves on the editorial boards of Rejuvenation Research and the Open Geriatric Medicine Journal and served for 16 years as a Director of the American Aging Association and for 6 years as the editor of AGE News, the organization’s newsletter.

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Serine + Vitamin B6: The Best Way To Reduce Homocysteine? (Also, Homocysteine Activates mTORC1)

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