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An Alzheimer’s-Proof Brain: Ground-Breaking Case Provides Clues to Treatment and Prevention of Dementia

Due to a rare genetic mutation, Aliria Rosa Piedrahita de Villegas should have had Alzheimer’s.

Alzheimer’s disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common form of dementia and accounts for 60 to 80 percent of dementia cases. There is no current cure for Alzheimer’s disease, but there are medications that can help ease the symptoms.

FDA APPROVED Drug Reverses Vascular Aging in Mice!

https://youtu.be/8F6BYlhyOSA

Hey it’s Han from WrySci-HX talking about how the anti diabetic drug Empagliflozin, brand name Jardiance, has reversed signs of vascular aging in mice! Is this why we’re seeing its benefits in humans? More below ↓↓↓

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Oldest case of a rare genetic condition discovered

A group of international researchers has uncovered evidence of a super rare genetic condition that gives men an extra X chromosome, reporting the oldest clinical case of Klinefelter syndrome to date.

The evidence comes from a 1,000-year-old skeleton from Portugal.

Klinefelter syndrome is a where individuals are born with an extra copy of the X chromosome, occurring in approximately one in 1,000 genetic-male births.

Frankenstein: Scientists create embryo with brain and beating heart entirely from stem cells

In a report this week from the science journal SciTechDaily, we learn of a scientific breakthrough that it clearly intended to be exciting and startling, but potentially worrisome as well. Scientists at the University of Cambridge have created a series of “model embryos” that include a functioning brain, a beating heart, and the foundation for all of the other bodily organs you would expect.

Remote heart rate sensors can be biased against darker skin. UCLA team offers solution

As telemedicine has grown more popular, so have devices that allow people to measure their vital signs from home and transmit the results by computer to their doctors. Yet in many cases, obtaining accurate remote readings for people of color has proved a persistent challenge.

Take remote heart rate measurements, for example, which rely on a camera sensing subtle changes in the color of a patient’s face caused by fluctuations in the flow of blood beneath their skin. These devices, part of an emerging class of remote technologies, consistently have trouble reading color changes in people with darker skin tones, said Achuta Kadambi, an assistant professor of electrical and computer engineering at the UCLA Samueli School of Engineering.

Kadambi and his team have now developed a remote diagnostic technique that overcomes this against darker skin while also making heart rate readings more accurate for patients across the full range of skin tones. Their secret? Combining the light-based measurements of a camera with radio-based measurements from radar.

AI could revolutionize healthcare but can we trust it?

The tool can identify symptoms of dengue, malaria, leptospirosis, and scrub typhus.

The study investigates both statistical and machine learning approaches. WHO has categorized dengue as a “neglected tropical disease.”

A prediction tool based on multi-nominal regression analysis and a machine learning algorithm was developed.

Accurate diagnosis is essential for the proper treatment and ensuring the well-being of patients. However, some diseases present with similar clinical symptoms and laboratory results, making diagnosing them more challenging.


Artificial Intelligence is perhaps the most promising technology for transforming our lives — but it’s also incredibly scary. At CES 2022, A panel of AI experts discussed what role AI might play in the future of healthcare.

In a session titled “Consumer Safety Driven by AI,” Pat Baird, an AI engineer and software developer who works in standards and regulations for Phillips, and Joseph Murphy, VP Marketing at Sensory Inc., an American technology company that develops AI products, discussed what AI could add to our lives. They also discussed the apprehension many people feel about the technology.

Artificial womb possibility

Biomedical researchers working with lambs got promising results from an experiment designed to prevent the health problems associated with premature births.

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Scientists Grow “Synthetic” Embryo With Brain and Beating Heart — Without Eggs or Sperm

We have arrived at Aldous Huxleys Brave new world.


Scientists from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body. It represents a new avenue for recreating the first stages of life.

The team of researchers, led by Professor Magdalena Zernicka-Goetz, developed the embryo model without eggs or sperm. Instead, they used stem cells – the body’s master cells, which can develop into almost any cell type in the body.

“It’s just unbelievable that we’ve got this far. This has been the dream of our community for years, and major focus of our work for a decade and finally we’ve done it.” —

Metformin & Rapamycin Show Combined Benefits in New Study

They boost each other and block side effects? (In mice)


Rapamycin and metformin are viewed by many as the two most promising anti-aging drugs, but now scientists have found that these drugs can work hand in hand and show combined benefits, boosting each other’s effectiveness and blocking side effects — or at least that’s what we’ve seen in mice.

When tested by the Intervention Testing Program metformin failed to significantly increase lifespan in mice. However, in combination with rapamycin, it worked synergistically, leading to a drastic increase in median and maximal lifespan.

In this new study, the researchers put the “combination hypothesis” to the test again, using male mice of a common pre-diabetes model. The mice received either rapamycin, metformin, or a combination from 12 to 30 weeks of age.

Being pre-diabetic, these mice usually gain a lot of weight with age. Metformin treatment did not alleviate this trend, but both the rapamycin and combination treatments allowed the mice to maintain normal weight until the end of the experiment.